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BME 695L Lecture 1: Need for New Perspectives on Medicine
31 Aug 2011 | Online Presentations | Contributor(s): James Leary
See references below for related reading.
1.1 Nanotechnology – Why is something so small so big?
1.1.1 Definitions of...
BME 695L Lecture 2: Designing Nanomedical Systems
See references below for related reading.
2.1 Elements of good engineering design
2.1.1 Whenever possible, use a general design...
Illinois ABE 446: Biological Nanoengineering
11 Feb 2010 | Courses | Contributor(s): Kaustubh Bhalerao
Nanodevice design through organization of functional biological components; bio-molecular function and bioconjugation techniques in nanotechnology; modulation of biological systems using...
Optical BioMEMS Microfluidic Technologies for Hand-Held, Point-of-Care, Medical Devices
23 Nov 2009 | Online Presentations | Contributor(s): James Leary
Portable, point-of-care, medical diagnostic devices could provide an important new component in more cost-effective healthcare delivery. Rapid measurements of blood samples during an examination...
Cataract, Myopathy and Keratitis: Possible use of Nanoparticles
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16 Sep 2008 | Online Presentations | Contributor(s): Ch. Mohan Rao
Small heat shock proteins are critical for several cellular functions. Failure of heat shock proteins, thus, can cause compromised cellular activity leading to disease. Fungal Keratitis is an eye...
Nanomaterials for Bone & Neural Tissue Engineering
11 Sep 2008 | Online Presentations | Contributor(s): S. Swaminathan
Tissue engineering is defined as “the application of biological, chemical and engineering principles towards the repair, restoration or regeneration of tissues using scaffolds, cells, factors...
The Functional Protocell concept
24 Mar 2008 | Online Presentations | Contributor(s): Eric Jakobsson
We have invented and created the first prototype of the Functional Protocell.
We define the “functional protocell" as a nanoporous solid surrounded by a membrane. The cavities in the solid can...
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14 Feb 2008 | Tools | Contributor(s): David Papke, Reza Toghraee, Umberto Ravaioli, Ankit Raj
Simulates ion flow through a channel.
BME 695N Lecture 21: FDA and EPA Regulatory Issues
27 Nov 2007 | Online Presentations | Contributor(s): James Leary
Introduction and overview
How does the FDA think about nanomedical systems?
The 2006 Nanotechnology Task Force
Some details of the Nanotechnology Task Force...
BME 695N Lecture 17: Assessing nanotoxicity at the single cell level
06 Nov 2007 | Online Presentations | Contributor(s): James Leary
Outline – the need for single cell measures of nanotoxicity
There is more than one way for a cell to die...
Necrosis" vs. "Apoptosis"
There are other forms of...
KIST/PU 2nd Annual Symposium: Molecular Imaging and Theragnosis
23 Oct 2007 | Workshops
This symposium presents an overview of the research of the Global Research Laboratory (GRL), a program that reflects a direct collaboration of scientific research between South Korea (Korea...
BME 695N Lecture 11: Construction of biomolecule conjugated nanoparticles
30 Sep 2007 | Online Presentations | Contributor(s): Don Bergstrom
With Donald E. Bergstrom as guest lecturer.
BME 695N Lecture 6: Rare-event targeting of cells in-vitro and in-vivo
26 Sep 2007 | Online Presentations | Contributor(s): James Leary
Assessing nanomedical system (NMS) targeting at the single cell level
Fluorescent labeling of NMSs
First estimates of NMS binding by fluorescence microscopy
Internal of external...
BME 695N Lecture 10: Nanomaterials for core design
Core building blocks
Functionalizing the core surface
Ferric oxide cores
BME 695N Lecture 8: Technologies for measuring nanomedical systems on/within cells
24 Sep 2007 | Online Presentations | Contributor(s): James Leary
Introduction to measuring technologies for nanomedical system interaction with cells
The importance of quantitative or at least semi-quantitative single cell measurements
BME 695N Lecture 7: Normal & facilitated cell entry mechanisms
15 Sep 2007 | Online Presentations | Contributor(s): James Leary
The general problem of cell entry
Choosing modes of cell entry
How does Nature do it? (biomimetics)
Non-specific uptake mechanisms
Pinocytosis by all...
BME 695N Lecture 5: Cell Targeting
12 Sep 2007 | Online Presentations | Contributor(s): James Leary
Overview: targeting nanosystems to cells
Antibodies – polyclonal and monoclonal
Where do antibodies come from – in...
BME 695N Lecture 4: Designing "Theragnostic" Systems
04 Sep 2007 | Online Presentations | Contributor(s): James Leary
Bridging the gap between diagnostics and therapeutics
How conventional medicine is practiced in terms of diagnostics and therapeutics
The consequences of separating diagnostics and...
BME 695N Lecture 3: Overview of Basic Nanomedical Systems Design
29 Aug 2007 | Online Presentations | Contributor(s): James Leary
Nanomedical systems – levels of challenges
Essential elements of a nanomedical system
Requirements for specific cell targeting
Consequences of mis-targeting
Engineering around the...
BME 695N: Engineering Nanomedical Systems (Fall 2007)
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28 Aug 2007 | Courses | Contributor(s): James Leary
This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell...