How Simple Cell-Cell Interactions Lead to Complex Multicellular Dynamics
04 Feb 2021 | | Contributor(s):: Paul Macklin
In this talk, we use agent-based simulation models to simulate (1) individual cell behaviors, (2) cell-cell interactions, and (3) cell-environment interactions to show how simple rules can give rise to complex multicellular phenomena. We showcase and explore free, interactive online tools to...
Biology of COVID-19 Attack on Epithelial Cells, understood from a Modeling and Simulation Perspective
n this session, we describe a community-driven effort to iteratively develop a multiscale, spatially-resolved open source model of SARS-CoV-2 dynamics and immune response in tissues.
Soft Materials for Studying Hard Biological Problems
15 Oct 2019 | | Contributor(s):: Kristi S. Anseth
This talk will illustrate how we leverage these and other reversible chemistries to create biologically responsive hydrogel matrices, and employ them to study the effects of matricellular signaling on diverse cellular functions and processes. For example, we exploit...
CELL-MET Thrust Area 2: Nanomechanics: Mechanical Properties of Materials, Scaffolds and Cardiac Tissues
04 Apr 2019 | | Contributor(s):: Pranjal Nautiyal
In this presentation, FIU graduate student Pranjal Nautiyal explains his work on Nanomechanics in Arvind Agarwal's Lab.
CELL-MET Thrust Area 2 - Nanomechanics: Cell-Integrated Surface Plasmon Resonance
08 Feb 2019 | | Contributor(s):: Maedeh Mozneb, CELL-MET ERC
In this presentation, FIU graduate student Maedeh Mozneb explains her work on Nanomechanics in Chen-Zhong Li’s lab.
Inference from Single Molecules to Cells
19 Jan 2017 | | Contributor(s):: Steve Pressé
Pulsed Power as an Enabling Technology for Cellular Manipulation and Cancer Treatment
02 Dec 2016 | | Contributor(s):: Allen Garner
Ongoing research explores the application of pulsed power for biomedical applications, including athermal sterilization of milk, water, and juices, cancer treatment, permeabilization of cells and tissues for drug delivery, and even wound healing. This lecture will provide a general overview...
Tissue-Level Communication Through Patterning Of Intercellular Ca2+ Wave Dynamics
22 Nov 2016 | | Contributor(s):: Jeremiah J. Zartman
Here we characterize periodic intercellular Ca2+ waves (ICWs) in a model organ system of epithelial growth and patterning—the Drosophila wing imaginal disc. We developed a novel regulated environment for micro-organs (REM-Chip) device that enable a broad range of genetic, chemical and...
The Epithelial-Mesenchymal Transition Its role in metastasis? Can Theory Help Cancer Biology?
19 Oct 2016 | | Contributor(s):: Herbert Levine
In order to spread from the primary tumor to distant sites, cancer cells must undergo a coordinated change in their phenotypic properties referred to as the "epithelial-to-mesenchymal" transition. We have studied the nonlinear genetic circuits that are responsible for this...
Collective Sensing by Communicating Cells
22 Sep 2016 | | Contributor(s):: Andrew Mugler
In this talk I will describe recent theoretical and experimental results in which this question is explored in several contexts, including gradient detection by groups of epithelial cells. I will show how communication allows cells to perform qualitatively new behaviors that single cells cannot...
Photonic Crystal Enhanced Microscopy (PCEM) for Studying the Invasiveness of Glioblastoma Multiforme (GBM) Cells
08 Jul 2016 | | Contributor(s):: Lydia Kwon
Bionanotechnology Seminar Series
[Illinois] Rare Events with Large-Impact: Bioengineering & Clinical Applications of Circulating Tumor Cells
04 Feb 2016 | | Contributor(s):: Mehmet Toner
[Illinois] Role for Stiffness in Vascular Fate
29 Jan 2016 | | Contributor(s):: Lian Wong
Stem cells, including embryonic stem cells (ESC) and induced pluripotent stem cells, have been explored as tools for studying development, as well as, potential sources for a large number of therapies in regenerative medicine. Traditionally, ESC are cultured on TC-plastic, however; it has been...
[Illinois] Advances in Nanoindentation Techniques for Wood Cell Walls
18 Sep 2015 | | Contributor(s):: Joseph Jakes
[Illinois] Nanomechanics of adherent cells
18 Sep 2015 | | Contributor(s):: Richard Chadwick
[Illinois] Nanomechanics of nonadherent cells
Single Molecule Imaging in Live Cells
28 Aug 2015 | | Contributor(s):: Kenneth Ritchie
Bacteria, such as Escherichia coli and Caulobacter crescentus, are the most studied and perhaps best-understood organisms in biology. The advances in understanding of living systems gained from these organisms are immense....
[Illinois] Knowledge, Context, and Process: Building a Foundational Infrastructure for Engineering Cells for Use in an Uncertain World
18 Aug 2015 | | Contributor(s):: Adam Arkin
Both natural and synthetically augmented organisms, like those engineered to produce advanced biofuels, ultimately have to operate in an uncertain world. Resources change, contact with other life, and yield surprising interactions, and in some cases, changes in one’s own genetic code lead...
Iterative Solution Method for an Implicit Orbit Averaged Particle-in-Cell Model
18 Aug 2015 | | Contributor(s):: Benjamin Sturdevant
Present kinetic simulations of turbulence in magnetized plasmas employ models from gyrokinetic theory, which is based on a number of ordering assumptions used to reduce the Vlasov-Maxwell system to eliminate high frequency phenomena. Recently, a second order accurate, implicit particle-in-cell...
[Illinois] Mechanical Design Considerations for Stretchable Cell Culture Systems
08 Aug 2014 | | Contributor(s):: Chelsey Simmons