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Cell Factory for Small Molecule Inducible Delivery of Low Dose IL-2
31 Aug 2023 | | Contributor(s):: Celsa Pachlhofer, Yafet Arefeayne, Rice University
Autoimmune and inflammatory diseases are characterized by insufficient regulatory T cells (Treg), which play a central role in maintaining peripheral tolerance, preventing autoimmunity, and limiting chronic inflammation. Treg cells depend on IL-2 for survival and maintenance of their...
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NanoMedicine
07 Oct 2022 | | Contributor(s):: Jared Ashcroft, NACK Network
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Nanotechnology: The Future of Medicine?
28 Jul 2022 | | Contributor(s):: Jared Ashcroft, The Micro Nano Technology - Education Center
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Agent Based Active Matter Simulations with Mechanica
14 Nov 2021 | | Contributor(s):: Somogyi, Andy T
Mechanica is an interactive mesh-free, chemistry and biology simulation environment, with an emphasis towards enabling users to model and simulate complex sub-cellular and cellular biological physics problems. Mechanica is designed first and foremost to enable users to work interactively...
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How Simple Cell-Cell Interactions Lead to Complex Multicellular Dynamics
04 Feb 2021 | | Contributor(s):: Paul Macklin
In this talk, we use agent-based simulation models to simulate (1) individual cell behaviors, (2) cell-cell interactions, and (3) cell-environment interactions to show how simple rules can give rise to complex multicellular phenomena. We showcase and explore free, interactive online tools to...
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Biology of COVID-19 Attack on Epithelial Cells, understood from a Modeling and Simulation Perspective
04 Feb 2021 | | Contributor(s):: Paul Macklin
n this session, we describe a community-driven effort to iteratively develop a multiscale, spatially-resolved open source model of SARS-CoV-2 dynamics and immune response in tissues.
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Soft Materials for Studying Hard Biological Problems
15 Oct 2019 | | Contributor(s):: Kristi S. Anseth
This talk will illustrate how we leverage these and other reversible chemistries to create biologically responsive hydrogel matrices, and employ them to study the effects of matricellular signaling on diverse cellular functions and processes. For example, we exploit...
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CELL-MET Thrust Area 2: Nanomechanics: Mechanical Properties of Materials, Scaffolds and Cardiac Tissues
04 Apr 2019 | | Contributor(s):: Pranjal Nautiyal
In this presentation, FIU graduate student Pranjal Nautiyal explains his work on Nanomechanics in Arvind Agarwal's Lab.
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CELL-MET Thrust Area 2 - Nanomechanics: Cell-Integrated Surface Plasmon Resonance
08 Feb 2019 | | Contributor(s):: Maedeh Mozneb, CELL-MET ERC
In this presentation, FIU graduate student Maedeh Mozneb explains her work on Nanomechanics in Chen-Zhong Li’s lab.
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Inference from Single Molecules to Cells
19 Jan 2017 | | Contributor(s):: Steve Pressé
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Pulsed Power as an Enabling Technology for Cellular Manipulation and Cancer Treatment
02 Dec 2016 | | Contributor(s):: Allen Garner
Ongoing research explores the application of pulsed power for biomedical applications, including athermal sterilization of milk, water, and juices, cancer treatment, permeabilization of cells and tissues for drug delivery, and even wound healing. This lecture will provide a general overview...
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Tissue-Level Communication Through Patterning Of Intercellular Ca2+ Wave Dynamics
22 Nov 2016 | | Contributor(s):: Jeremiah J. Zartman
Here we characterize periodic intercellular Ca2+ waves (ICWs) in a model organ system of epithelial growth and patterning—the Drosophila wing imaginal disc. We developed a novel regulated environment for micro-organs (REM-Chip) device that enable a broad range of genetic, chemical and...
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The Epithelial-Mesenchymal Transition Its role in metastasis? Can Theory Help Cancer Biology?
19 Oct 2016 | | Contributor(s):: Herbert Levine
In order to spread from the primary tumor to distant sites, cancer cells must undergo a coordinated change in their phenotypic properties referred to as the "epithelial-to-mesenchymal" transition. We have studied the nonlinear genetic circuits that are responsible for this...
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Collective Sensing by Communicating Cells
22 Sep 2016 | | Contributor(s):: Andrew Mugler
In this talk I will describe recent theoretical and experimental results in which this question is explored in several contexts, including gradient detection by groups of epithelial cells. I will show how communication allows cells to perform qualitatively new behaviors that single cells cannot...
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Photonic Crystal Enhanced Microscopy (PCEM) for Studying the Invasiveness of Glioblastoma Multiforme (GBM) Cells
08 Jul 2016 | | Contributor(s):: Lydia Kwon
Bionanotechnology Seminar Series
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E304 L10.1.2: Nanobiotechnology - Information Storage and Retrieval in the Cell
14 Jun 2016 | | Contributor(s):: ASSIST ERC
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E304 L10.1.3: Nanobiotechnology - Energy Generation and Storage Within the Cell
14 Jun 2016 | | Contributor(s):: ASSIST ERC
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[Illinois] Rare Events with Large-Impact: Bioengineering & Clinical Applications of Circulating Tumor Cells
04 Feb 2016 | | Contributor(s):: Mehmet Toner
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[Illinois] Role for Stiffness in Vascular Fate
29 Jan 2016 | | Contributor(s):: Lian Wong
Stem cells, including embryonic stem cells (ESC) and induced pluripotent stem cells, have been explored as tools for studying development, as well as, potential sources for a large number of therapies in regenerative medicine. Traditionally, ESC are cultured on TC-plastic, however; it has been...
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[Illinois] Advances in Nanoindentation Techniques for Wood Cell Walls
18 Sep 2015 | | Contributor(s):: Joseph Jakes