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[Illinois] Mechanical Design Considerations for Stretchable Cell Culture Systems
08 Aug 2014 | | Contributor(s):: Chelsey Simmons
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[Illinois] Biomaterials to Replicate the Form and Function of Inhomogeneous Structures in the Body
28 Apr 2014 | | Contributor(s):: Brendan Harley
The extracellular matrix (ECM) is a complex organization of structural proteins such as collagens and proteoglycans. Understanding that the ECM is dynamic and often spatially patterned or heterogeneous over the length-scale of traditional biomaterials, we are developing instructive biomaterials...
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[Illinois] Peptide Release from the Cells of the Dorsal Root Ganglion upon Application of Tensile Strain
04 Feb 2014 | | Contributor(s):: Emily Tillmaand
Morphological and electrophysiological studies have shown that neurons respond to specific mechanical environments. However, studies linking specific neuropeptide release based on changes in the mechanical environment are lacking. To further study the effect of mechanical stress on the cells of...
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[Illinois] BioNanotechnology Seminar Series Fall 2011: Bio-inspired Microenvironments Regulate Cell Fate
14 Jun 2013 | | Contributor(s):: Adam Engler
Epigenetic regulation of stem cell fate by intrinsic properties of the surrounding extracellular matrix (ECM), e.g. stiffness, organization, composition, etc., appears to be an important yet underappreciated contributor in development, disease, and aging. I will describe our efforts to develop...
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[Illinois] CMMB IGERT & M-CNTC Annual Symposium: Program Overview
06 Jun 2013 | | Contributor(s):: Taher A. Saif
The second annual CMMB IGERT PI and Trainee Meeting was held on August 31, 2011. Dr. Saif walks through the goals and current status of the programs, and introduces the students involved.
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[Illinois] Bionanotechnology Seminar Series Fall 2012: Mechanical Property Characterization for 3D Collagen Cancer Cell Cultures
08 Mar 2013 | | Contributor(s):: Yue Wang
The tumor microenvironment is mechanically modified during cancer progression. Imaging of tumor mechanical environment will provide new information for early cancer diagnosis. However, it is less clear how the mechanical environment is tuned in cancer. The goal of this study is to understand more...
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[Illinois] CPLC Seminar Series: Living Cell Studies Assisted by Nanoengineering Surfaces
26 Nov 2012 | | Contributor(s):: Logan Liu
It is known that living cells interact with their micro and nanoscale environments. We created a variety of nanoengineered surfaces which can interact with living cells grown on top. Two particular examples will be demonstrated. The first one is ultrasensitive 3D confocal fluorescence microscopy...
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In Living Motion: Imaging Cellular Function in Live Tissues
21 Aug 2012 | | Contributor(s):: David D. Nolte
Subcellular motions inside live tissue are sensitive indicators of cellular health and cellular response to applied drugs. Digital holography volumetrically captures these motions in tissue dynamics spectroscopy for live-tissue drug screening.
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Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy
05 Dec 2011 | | Contributor(s):: Li Tang
Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer treatment. The size of these drug delivery vehicles has been strongly correlated with their in...
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Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements
05 Dec 2011 | | Contributor(s):: Elise Corbin
The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through which a cell's physical properties influence cell growth, cell differentiation, cell cycle...
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BME 695L Special Lecture 4: Atomic Force Microscopy (AFM) for Nanomedical Systems (cells and nanoparticles)
02 Dec 2011 | | Contributor(s):: Helen McNally
Guest lecturer: Helen McNally
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BME 695L Lecture 12: Assessing Drug Efficacy and Nanotoxicity at the Single Cell Level
22 Nov 2011 | | Contributor(s):: James Leary
See references below for related reading.12.1 Introduction to measures of efficacy for nanomedicine12.1.1 for evaluation purposes, does structure/size reveal function?12.1.2 nanomedical treatment at the single cell...
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BME 695L Special Lecture 2: X-ray Photoelectron Spectroscopy (XPS) in Biologically-Relevant Applications
01 Nov 2011 | | Contributor(s):: Dmitry Zemlyanov
Guest lecturer: Dmitry Zemlyanov
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BME 695L Lecture 11: Assessing Nanotoxicity at the Single Cell Level
27 Oct 2011 | | Contributor(s):: James Leary
See references below for related reading.11.1 Need for single cell measures of nanotoxicity11.1.1 There is more than one way for a cell to die...11.1.2 "Necrosis" vs. "Apoptosis"11.1.3 There...
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Discussion about Ion Channels Using Reduced Model Approaches
21 Sep 2011 | | Contributor(s):: James Fonseca
The seminar will cover the reasons how the channels are able to selectively permit the flow of certain species of ions while blocking other physiological cations.
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Nano*High: X-rays, Lasers, and Molecular Movies
25 Sep 2010 | | Contributor(s):: Roger W. Falcone
X-ray imaging is an excellent method to make visible what would normally be invisible - who hasn't had an X-ray at the doctor or dentist's office before? At the Lawrence Berkeley National Lab, the Advanced Light Source is a gigantic X-ray imaging machine. Dr. Roger Falcone discusses X-ray...
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2010 Nano-Biophotonics Summer School @ UIUC Lecture 5 - Biomedicine - A tour of the Cell
25 Sep 2010 | | Contributor(s):: Marina Marjanovic
Edited and Uploaded by Omar Sobh, University of Illinois at Urbana-Champaign
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Nanomedicine – How Can Something so Small be so Huge for the Future of Healthcare?
17 Jun 2010 | | Contributor(s):: James Leary
Dr. James Leary discusses the future on medicine and the impact nanotechnology will have on healthcare.
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ECET 499N Lecture 12: Scanning Probe Microscopy Applications (in Neuroscience and Beyond)
12 Apr 2010 | | Contributor(s):: Helen McNally
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Illinois Phys550 Molecular Biophysics Lecture 2: Compartmentalization of Cells, Photosynthesis II
26 Jan 2010 | | Contributor(s):: Klaus Schulten
Compartmentalization of cells, photosynthesis (part 2 of 2)