Tags: cellular decision-making

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  1. The Epithelial-Mesenchymal Transition Its role in metastasis? Can Theory Help Cancer Biology?

    19 Oct 2016 | | Contributor(s):: Herbert Levine

    In order to spread from the primary tumor to distant sites, cancer cells must undergo a coordinated change in their phenotypic properties referred to as the "epithelial-to-mesenchymal" transition.  We have studied the nonlinear genetic circuits that are responsible for this...