All Categories (1-4 of 4)

1. CompuCell3D model: Senescent mesothelial clearance by ovarian cancer cells

   19 Nov 2022 | Contributor(s):: Bharat Vivan Thapa, Ramray Bhat, Tilmann Glimm

   A compuCell3D model to show how cancer cells eliminate senescent mesothelial cells more efficiently than non-senescent mesothelial cells.

2. [Illinois] Extracellular Matrix Remodeling during Cancer Progression and Metastasis

   09 Oct 2014 | Contributor(s):: Manu Platt

3. [Illinois] CMMB IGERT & M-CNTC Annual Symposium: Cell Mechanosensitivity and Metastasis

   06 Jun 2013 | | Contributor(s):: Xin Tang

   Human colon carcinoma (HCT-8) cells show a stable transition from low to high metastatic state when cultured on appropriately soft substrates (21 kPa). Initially epithelial (E) in nature, the HCT-8 cells become rounded (R) after seven days of culture on soft substrate. R cells show a number of...

4. [Illinois] Cancer Community Symposium 2012: T Cell Receptors For Potential Cancer Immunotherapy Applications: Single Chain T Cell Receptors Circumvent Mispairing with Endogenous TCR and Mediate T Cell Activity

   09 May 2012 | | Contributor(s):: David H. Aggen

   To improve the immune response to cancer, gene therapy with tumor-specific T cell-receptors (TCRs) provides an attractive approach to effectively arm patients T cells for tumor cell destruction. A high-affinity TCR specific for an antigenic peptide-major histocompatibility complex (pepMHC) can be...