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Quantitative, Kinetic Models of Cellular Circuits
04 Apr 2009 | | Contributor(s):: Michael R. Brent
Living cells contain complex, analog circuits that regulate the rate at which each gene produces its product. The kinetic properties of these circuits enable cells to respond to changes in their environments and thus to survive, reproduce, and compete. For decades, molecular biologists have been...
"Who Owns Truth?" - Biomedical Research in a Health Policy Context
30 Mar 2009 | | Contributor(s):: Samuel A. Richmond
This presentation examines a claim made by PhRMA on behalf of pharmaceutical manufacturing companies of America, and the response of the International Committee of Medical Journal Editors (ICMJE) questioning drug company publication policies and practices. Also considered are changes in law...
Illinois nanohour Seminar: Rapid Label Free Detection of Rotavirus using Photonic Crystal Biosensors
05 Mar 2009 | | Contributor(s):: Leo L Chan
Rapid Label-free Detection of Rotavirus using Photonic Crystal Biosensors Presentation Outline Rotavirus Current Detection Method Label-based versus label-free assay Photonic Crystal (PC) Biosensor Biosensor Fabrication Biosensor Operation Assay Protocol Titration Series Comparison with ELISA...
Illinois PHYS 466, Lecture 9: Probability tools & Random number generators
03 Mar 2009 | | Contributor(s):: David M. Ceperley
Random Number Generation (RNG)read “Numerical Recipes” on random numbers and chi-squared testToday we discuss how to generate and test random numbers.What is a random number? A single number is not random.Only an infinite sequence can be described as random. Random means the absence of order....
Illinois PHYS 466, Lecture 8: Temperature and Pressure Controls
Temperature and Pressure ControlsContent: Constant Temperature MD Quench method Brownian dynamics/Anderson thermostat Nose-Hoover thermostat (FS 6.1.2) Nose-Hoover thermodynamics Effect of thermostat Comparison of Thermostats Constant pressure or constant volume Constant Pressure (FS 6.2)...
Illinois PHYS 466, Lecture 6: Scalar Properties and Static Correlations
Scalar Properties, Static Correlations and Order ParametersWhat do we get out of a simulation? Static properties: pressure, specific heat, etc. Density Pair correlations in real space and Fourier space Order parameters and broken symmetry: How to tell a liquid from a solid Dynamical properties...
Illinois nanohour Seminar: Label-Free Biosensor Based upon Replica-Molded Vertically Emitting Distributed Feedback Laser
02 Mar 2009 | | Contributor(s):: m lu
Label-Free Biosensor Based upon Replica-Molded Vertically Emitting Distributed Feedback LaserPresentation Outline State of the art of label-free optical biosensor Biosensor using active optical resonator Design, optimization, fabrtication, and characterization of DFB laser biosensor Interaction...
Basic Rules of Protein Folding
out of 5 stars
31 Dec 2008 | | Contributor(s):: Seth Lichter
How are proteins made? Inside cells, messenger RNA first instructs the ribosomes as to the order which amino acids should be joined together. Linked together and released from the ribosome, the protein is not functional. It now needs to fold into a precise three-dimensional shape. There are no...
The Opposite of Human Enhancement: Nanotechnology and the Blind Chicken Problem
20 Oct 2008 | | Contributor(s):: Paul B. Thompson
Hydration Dynamics in an Amphiphilic Nanostructure under Controlled Hydration Conditions
16 Sep 2008 | | Contributor(s):: Amitabha Chattopadhyay
Amphiphilic surfactants self assemble to form reverse (or inverted) micelles in non-polar solvents in which the polar head groups of the surfactant monomers cluster to form a micellar core directed toward the center of the assembly and the hydrophobic tails extend outward into the bulk organic...
Cataract, Myopathy and Keratitis: Possible use of Nanoparticles
16 Sep 2008 | | Contributor(s):: Ch. Mohan Rao
Small heat shock proteins are critical for several cellular functions. Failure of heat shock proteins, thus, can cause compromised cellular activity leading to disease. Fungal Keratitis is an eye dieses that can be treated with anti fungal drugs. Availability of the drug at the site of action is...
Nanomaterials for Bone & Neural Tissue Engineering
11 Sep 2008 | | Contributor(s):: S. Swaminathan
Tissue engineering is defined as “the application of biological, chemical and engineering principles towards the repair, restoration or regeneration of tissues using scaffolds, cells, factors alone or in combination.” The goal lis to design and develop biodegradable, biocompatible...
So What do Biologist, Biotechnologists & Pharmaceutical Scientist Want With an AFM/SPM Anyway?
11 Sep 2008 | | Contributor(s):: Kunal Bose
Self-assembled Monolayer Based Biosensors for Healthcare
06 Aug 2008 | | Contributor(s):: B. D. Malhotra
There is increased demand both in developed and the developing countries for ready availability of biosensors [1-5]. In this context, self-assembled monolayer (Scheme I) based biosensors have recently attracted much interest due to their applications in health care, environmemtal,...
Nanomaterials in Biosensing Using Ion Selective Field Effect Transistors and Metal Particles
30 Jul 2008 | | Contributor(s):: Nalam Madhusudhana Rao
The multifunctionality, multilayerable architechture and size of nanomaterials offer tremendous opportunities in developing sensing platforms. Ion Selective Field Effect Transistors (ISFET) are solid state and robust pH/ion sensing devices with excellent “voltage vs. ion concentration”...
Nanocomposite-Modified Electrodes for Sensing Biological Analytes
30 Jul 2008 | | Contributor(s):: V. Yegnaraman
Electrochemical sensing of analytes is mostly enabled by transducers based on potentiometry and amperometry. In this, design of sensing (working) electrode is of utmost importance since it only decides the sensitivity and selectivity features of the sensor. Chemical modification of the electrode...
Micro-fabricated Biosensors for Cardiac Diagnostics
30 Jul 2008 | | Contributor(s):: V.Ramgopal Rao
In this talk the current status of an ongoing effort in the Electrical Engineering Department at IIT Bombay on the development of an integrated systems to provide point-of-care diagnostic support for cardiovascular diseases will be presented. The system under development monitors the molecular...
Self-association of peptides and proteins: Retrospect and prospects
30 Jul 2008 | | Contributor(s):: R. Nagaraj
The ability of peptides and proteins to form aggregates was known from the dawn of protein and peptide chemistry! It was often considered a nuisance and attention was directed towards disaggregating them to ensure dissolution particularly in aqueous solution. X-ray crystallography has indicated...
Use of Ceramic based biomaterials for their application in vitro osteogenic differentiation
30 Jul 2008 | | Contributor(s):: Gopal Pande
The use of bioceramics for preparation of implants and prosthesis for applications in orthopedic surgery has been done over several years. Recently new formulations for making substrates and coatings using ceramic material such as alumina, bioglass or zirconia have been done for improved...
Nanobiotechnology – a different perspective
22 Jul 2008 | | Contributor(s):: Murali Sastry
The study of the synthesis, exotic properties, assembly/packaging and potential commercial application of nanomaterials is an extremely important topic of research that is expected to have far-reaching global impact. The focus of my talk will be on an emerging branch of nanotechnology that...