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From density functional theory to defect level in silicon: Does the “band gap problem” matter?
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01 Oct 2008 | | Contributor(s):: Peter A. Schultz
Modeling the electrical effects of radiation damage in semiconductor devices requires a detailed description of the properties of point defects generated during and subsequent to irradiation. Such modeling requires physical parameters, such as defect electronic levels, to describe carrier...
Quantum and Thermal Effects in Nanoscale Devices
18 Sep 2008 | | Contributor(s):: Dragica Vasileska
To investigate lattice heating within a Monte Carlo device simulation framework, we simultaneously solve the Boltzmann transport equation for the electrons, the 2D Poisson equation to get the self-consistent fields and the hydrodynamic equations for acoustic and optical phonons. The phonon...
Current research in nanoelectronics
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i am a student doing my graduate studies and would like to the current research thats going on in the field of nanoelectronics and nano cmos..
Hydration Dynamics in an Amphiphilic Nanostructure under Controlled Hydration Conditions
16 Sep 2008 | | Contributor(s):: Amitabha Chattopadhyay
Amphiphilic surfactants self assemble to form reverse (or inverted) micelles in non-polar solvents in which the polar head groups of the surfactant monomers cluster to form a micellar core directed toward the center of the assembly and the hydrophobic tails extend outward into the bulk organic...
Cataract, Myopathy and Keratitis: Possible use of Nanoparticles
16 Sep 2008 | | Contributor(s):: Ch. Mohan Rao
Small heat shock proteins are critical for several cellular functions. Failure of heat shock proteins, thus, can cause compromised cellular activity leading to disease. Fungal Keratitis is an eye dieses that can be treated with anti fungal drugs. Availability of the drug at the site of action is...
Nanomaterials for Bone & Neural Tissue Engineering
11 Sep 2008 | | Contributor(s):: S. Swaminathan
Tissue engineering is defined as “the application of biological, chemical and engineering principles towards the repair, restoration or regeneration of tissues using scaffolds, cells, factors alone or in combination.” The goal lis to design and develop biodegradable, biocompatible...
So What do Biologist, Biotechnologists & Pharmaceutical Scientist Want With an AFM/SPM Anyway?
11 Sep 2008 | | Contributor(s):: Kunal Bose
Self-assembled Monolayer Based Biosensors for Healthcare
06 Aug 2008 | | Contributor(s):: B. D. Malhotra
There is increased demand both in developed and the developing countries for ready availability of biosensors [1-5]. In this context, self-assembled monolayer (Scheme I) based biosensors have recently attracted much interest due to their applications in health care, environmemtal,...
Nanomaterials in Biosensing Using Ion Selective Field Effect Transistors and Metal Particles
30 Jul 2008 | | Contributor(s):: Nalam Madhusudhana Rao
The multifunctionality, multilayerable architechture and size of nanomaterials offer tremendous opportunities in developing sensing platforms. Ion Selective Field Effect Transistors (ISFET) are solid state and robust pH/ion sensing devices with excellent “voltage vs. ion concentration”...
Nanocomposite-Modified Electrodes for Sensing Biological Analytes
30 Jul 2008 | | Contributor(s):: V. Yegnaraman
Electrochemical sensing of analytes is mostly enabled by transducers based on potentiometry and amperometry. In this, design of sensing (working) electrode is of utmost importance since it only decides the sensitivity and selectivity features of the sensor. Chemical modification of the electrode...
Micro-fabricated Biosensors for Cardiac Diagnostics
30 Jul 2008 | | Contributor(s):: V.Ramgopal Rao
In this talk the current status of an ongoing effort in the Electrical Engineering Department at IIT Bombay on the development of an integrated systems to provide point-of-care diagnostic support for cardiovascular diseases will be presented. The system under development monitors the molecular...
Self-association of peptides and proteins: Retrospect and prospects
30 Jul 2008 | | Contributor(s):: R. Nagaraj
The ability of peptides and proteins to form aggregates was known from the dawn of protein and peptide chemistry! It was often considered a nuisance and attention was directed towards disaggregating them to ensure dissolution particularly in aqueous solution. X-ray crystallography has indicated...
Use of Ceramic based biomaterials for their application in vitro osteogenic differentiation
30 Jul 2008 | | Contributor(s):: Gopal Pande
The use of bioceramics for preparation of implants and prosthesis for applications in orthopedic surgery has been done over several years. Recently new formulations for making substrates and coatings using ceramic material such as alumina, bioglass or zirconia have been done for improved...
<i>In Vivo</i> Nuclear Magnetic Resonance Imaging and Spectroscopic Investigations of Structure and Function of Rodent Brain
30 Jul 2008 | | Contributor(s):: Anant B. Patel
Nuclear Magnetic Resonance Imaging (MRI) is a powerful and a versatile imaging modality for non-invasive characterization of host structure and function. MRI has grown in many directions such as functional MRI, diffusion tensor imaging, chemical shift imaging, which is used to detect single...
Nanohybrids as Sensors and Superstructures
30 Jul 2008 | | Contributor(s):: K. George Thomas
We have recently initiated a detailed research program on the design of nanoparticle conjugates of organic/inorganic molecules which enable the coupling of the intrinsic functionalities of molecular systems (binding, self-assembly, switching etc.) with the size and shape dependent optoelectronic...
Nanobiotechnology – a different perspective
22 Jul 2008 | | Contributor(s):: Murali Sastry
The study of the synthesis, exotic properties, assembly/packaging and potential commercial application of nanomaterials is an extremely important topic of research that is expected to have far-reaching global impact. The focus of my talk will be on an emerging branch of nanotechnology that...
Transforming Pharmaceutical Manufacturing in the 21st Century – Indiana as a Center for Biopharmaceutical Manufacturing
21 Jul 2008 | | Contributor(s):: Craig K. Svensson
The pharmaceutical industry is moving from a model of fully integrated pharmaceutical companies to fully networked pharmaceutical companies. In this latter model, major pharmaceutical companies are increasingly relying on partnerships for critical elements in the drug development process. This...
Quality by Design and Process Analytical Technology for Pharmaceutical Manufacturing in the 21st Century
21 Jul 2008 | | Contributor(s):: Stephen R. Byrn
PAT or Process Analytical Technology is an initiative and guidance from the U.S. FDA to encourage modernization of pharmaceutical manufacturing. In reality, PAT is a subset of the larger concept of Quality by Design which is the implementation of design concepts for pharmaceutical dosage forms...
Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations
Nanoparticles hold great promise for drug delivery applications. Several polymer-based formulations containing nanoparticles are in late phase development or on the market. In fact, polymer dispersions provide one of the best methods to prepare nanoparticles of small-molecule organic drugs....
Multiplex Detection of Cell Surface Markers using Plasmonic Sensors
21 Jul 2008 | | Contributor(s):: Joseph M K Irudayaraj
Gold nanorod molecular probes (GNrMPs) were designed and fabricated for multiplex identification of cell surface markers in HBECs. Cells were probed directly using dark field microscopy integrated with a spectral imager for simultaneous detection of up to three surface markers. The...