PhysiCell simulation of GBM tumour under oHSV1 treatment
28 Mar 2021 | Contributor(s):: Adrianne Jenner, Randy Heiland, Paul Macklin
Simulation for GBM fragment growth under oHSV1 treatment published in Jenner et al. (2021)
Understanding COVID-19 Infection, Immune Response, and Drug Therapy through Multiscale, Multicellular Modeling and Simulation
10 Dec 2020 | | Contributor(s):: T.J. Sego
This workshop presents an open-source Python- and XML-scripted multiscale modeling and simulation framework of an epithelial tissue infected by a virus, a simplified cellular immune response and viral and immune-induced tissue damage and shows how to use it to model basic patterns of infection...
Saliva-Based Testing for COVID-19
22 Nov 2020 | | Contributor(s):: Mohit Verma
The Verma lab is developing a molecular test for SARS-CoV-2 that detects the RNA and produces a color change in less than one hour. Using saliva as the sample, this test is easier to use at the point-of-care.
A virion pharmacodynamics response tissue simulator
27 Jul 2020 | | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin
Simulate virus pharmacodynamics response with PhysiCell
A virion infected-cell response tissue simulator
13 Apr 2020 | | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin
Simulate infected cell response to virus with PhysiCell
A virion replication tissue simulator
Simulate virus replication dynamics with PhysiCell
A virion endocytosis tissue simulator
Simulate virus endocytosis (internalization), ACE2 receptor dynamics with PhysiCell
PhysiCell model for COVID19
26 Mar 2020 | | Contributor(s):: Randy Heiland, Yafei Wang, Paul Macklin
Prototype 2-D multicellular simulation of COVID19.
Replication Competent Oncolytic Virus expressing secretable trimeric TRAIL: hypothesis testing
23 Apr 2019 | | Contributor(s):: Adrianne Jenner, Paul Macklin
Using PhysiCell to simulate a replication competent oncolytic virus expressing secretable trimeric TRAIL which induces apoptosis in nearby cells
Replication Competent Oncolytic Virus in Epithelial cell layer
18 Apr 2019 | | Contributor(s):: Adrianne Jenner, Paul Macklin
PhysiCell simulation of a replication competent oncolytic virus release from two veins, diffusing through a layer of epithelial cells.