BioPHET: Electrostatic Free Energy of Immobilized Proteins on Charged Sufaces
Welcome to the BioPHET development area. This project is for people actively developing source code and documentation for this tool.
- GettingStarted - learn how to download the current code and make changes
- ToolInformation - describe your tool, its authors, and related materials
- TicketSystem - use trouble tickets to report problems and document ideas for future development
What is BioPHET?
Solves Poisson-Boltzmann equation and calculates electrostatic interaction free energy for proteins attached to biological and non-biological surfaces. Information on the orientation of proteins attached to surfaces is of great theoretical and practical interest due to the recent extensive use of immobilized proteins, and due to applications involving the catalytic potential of immobilized enzymes. This module uses PROPHET as a platform and offers numerical capabilities to calculate the electrostatic interaction free energy of protein/surface systems for different protein orientations. The prefered attachment orientation can then be obtained by finding the orientation with the minimum free energy.
How do I use this site?
You can edit any of the pages in this site and add information. For more instructions, see: