Nanobiotechnology Resources for K-12

by Malika Sen Datta, Lynn Zentner

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1 ===Resources for Grade School Students===
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3 [[http://www.nanozone.org Nanozone]]
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5 Nanozone, for kids ages 8-14, explores the basics of nanotechnology and nanoscience with games,videos and comics.
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7 [[http://www.molecularium.com/index2.html Molecularium Project]]
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9 The Molecularium Project provides educational tools and games for kids to learn and have fun with the nanoparticle world.
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11 [[http://www.playgen.com/home/content/view/30/26/ NanoMission]]
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13 Nanomission is a three dimensional learning game that promotes learning about molecular building, nanoimaging, creation of nanodevices, nanomedicine, quantum behavior, and manipulating electrons of nanomaterials.
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15 [[http://www.nisenet.org/catalog NISE Network Catalog]]
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17 The NISE Network Catalog contains many tools and guides, programs, and media dealing with nano-related art and nature, biology and medicine, energy and environment, fundamentals, information technology, applications, and society, policy, and economics.
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19 [[http://nanoyou.eu./en/virtual-lab/hands-on-activities.html?view=alphacontent NANOYOU]]
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21 NANOYOU (Nano for Youth) provides hands-on activities and labs dealing with nanoscience.
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'''Resources for High School Students and More'''
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===Resources for High School Students and More===
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25 [[http://www.virlab.virginia.edu/VL/contents.htm The Virginia Virtual Lab]]
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27 The University of Virginia Virtual Lab provides lecture notes, supporting animations, simulations, and readings so that high schoolers can learn more about nanoscience (including nanocarbon, nanotubes, DNA, and nanoscience instruments)
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29 [[https://nanohub.org/resources/2260 Nanobiotechnology and Biosensors]]
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31 This presentation is meant to provide an overview of the field of Nanobiotechnology and Bioelectronics with a focus on the development of electrical biosensors. It covers the principles, technologies, methods and applications of nanotechnology in the development of biosensors.
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33 [[https://nanohub.org/resources/4807 Nanobiotechnology-A different perspective]]
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35 In this presentation, Murali Sastry focuses on an emerging branch of nanotechnology that derives its inspiration from biology.
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37 [[https://nanohub.org/topics/NCNNano-DevicesforMedicineandBiology NCN Nano-Devices for Medicine and Biology]]
38 This NCN theme seeks to extend the understanding and computational tools developed in the Nanoelectronics and NEMS themes and apply them to the development of devices for medicine and biology
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40 [[https://nanohub.org/resources/11140 Illinois BioNanotechnology Seminar Series : Development of Anticancer Medicine]]
41 This presentation explores new developments in chemical and engineering processes to prepare anticancer nanomedicines.
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43 [[https://nanohub.org/resources/1093 Engineering Nanomedical Systems]]
44 This tutorial discusses general problems and approaches to the design of engineered nanomedical systems.
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46 [[https://nanohub.org/resources/4755 NCN Nano-Devices for Medicine and Biology: Tutorials]]
47 Here are a few tutorial lectures that convey new approaches to the development of new kinds of devices for applications in medicine and biology.
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49 [[/topics/k12 '''More Nanohub Resources for K-12''']]
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'''Resources for Teachers'''
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===Resources for Teachers===
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53 [[http://www.understandingnano.com/lesson-plan-nanomedicine-high-school.html Understanding Nano]]
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This lesson plan was created to help high school science teachers provide an introduction to nanomedicine.
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This lesson plan was created to help high school science teachers provide an introduction to nanomedicine.
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===Nanobiotechnology Tools===
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[[resources/biomoca The Biology Monte Carlo Demo (BioMOCA)]]: With the recent availability of high-resolution structure information for several key ion channel proteins and large-scale computational resources, Molecular Dynamics has become an increasingly popular tool for ion channel simulation.
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[[/resources/nanogromacsii NanoGromacs]]: NanoGromacs is an interface for molecular dynamic simulation using Gromacs. It can perform lipid and protein simulations on user provided structures. The users can upload their own input structures, select corresponding force field files and set the run-time parameters. The simulation result structure can be visualized using PyMOL on the nanoHUB. The interface also can show the dynamic effect of the simulation process. The simulation result also can be analyzed by utilities from Gromacs. The users can also download the result pdb file then use their favorite visualization tool like VMD or RasMol to view it locally. NanoGromacs simplifies the task of assembling the input files required. It ignores tedious command line execution of Gromacs. And it also provides users with visualization result and analysis tools.
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[[/resources/BMCsuite BioMOCA Suite]]: The BioMOCA Suite can perform ion channel flow simulations on any user supplied channel. The suite includes: a map generator subtool, which produces protein maps for BioMOCA from the supplied PQR file; a lipid wrapper subtool, which allows the user to embed their channel in a membrane; and the boundary force potential calculator, which determines the potential energy barrier presented by the channel. The user can also download the acc and charge files produced by the map generator and lipid wrapper.
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[[resources/cismcm Cyber-Infrastructure for Imaging and Simulation of Molecular and Cellular Mechanics (CISMCM)]]: This is a simulation-driven science project to understand the inner workings of cellular structures and biological systems, and to design detection and manipulation devices for a wide range of applications in nano-medicine and nano-biotechnology. Our specific plan focuses on two important and synergistic aspects of molecular and cell mechanics: a) analysis tools for nano-bio imaging and b) design tools for mechano-sensing devices.
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[[/resources/stretchmol Stretching Simulation of an Alpha-Helical Protein Domain]]: This tool uses steered molecular dynamics (SMD) to apply a tensile load to the ends of a molecule (such as an alpha-helical protein domain)
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[[/resources/nbrush Polymer Nano Brush]]: This tool calculates structural properties of polymer brushes using a molecular theory
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[[/resources/contactmaps Protein Contact Maps]]: This tool allows the user to easily generate contact maps and distance maps for protein molecules
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[[/resources/fpuf Forced Protein Unfolding]]: This tool enables users to easily perform non-equilibrium molecular dynamics simulations of a protein subject to an external force and then analyze their simulation results both quantitatively and through animations of the protein dynamics.
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[[/resources/hydrolab Hydrophobocity Lab]]: With this tool, the user will be able to tune the interaction between water and hydrocarbon chains (modeled by a single particle with an effective potential) and observe the changes in hydrophobicity and aggregation.
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[[/resources/senstran BioSensor Lab]]: This is a tool that evaluates and predicts the performance parameters of a label-free, electronic biosensor.
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[[/resources/pnppeptide Poisson-Nernst-Planck Cyclic Peptide Ion Channel Model]]: This tool simulates ion flow in a system modeled after cyclic peptide ion channels using Poisson-Nernst-Planck (PNP) theory.