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Your Smart Brain
21 Aug 2022 | | Contributor(s):: Rubiona Grainger, Rice University, NEWT Center
Researchers have differentiated hESCs into forebrain, midbrain and hindbrain. However, observing cell interpretation of signals to form dorsal-ventral patterning tissues with sonic hedgehog (SHH) gene is necessary. We used micropatterning within different timeframes to determine how cell fates...
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Neutral Pattering of Stem Cells
20 Aug 2022 | | Contributor(s):: Donna Booker, Rice University
How do cells pattern and establish the complex structures of the brain? How does a cell know that it will be part of the forebrain or the hindbrain? By using embryonic stem cells, this project focuses on researching how proteins and genes interact with each other to establish instructions...
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Building & Testing a Component of Synthetic Genetic Circuit in Mammalian Cells
20 Aug 2022 | | Contributor(s):: Ariel Delos Reyes, Rice University
Oscillations in protein levels within cells help facilitate a variety of biological processes, from circadian rhythm to cell cycle progression. This research focuses on developing a platform for creating oscillatory circuits in mammalian cells by using several interrelated DNA constructs....