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[Illinois] Nanomechanics of adherent cells
Online Presentations | 18 Sep 2015 | Contributor(s):: Richard Chadwick
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[Illinois] Nanomechanics of nonadherent cells
Online Presentations | 18 Sep 2015 | Contributor(s):: Richard Chadwick
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Single Molecule Imaging in Live Cells
Online Presentations | 28 Aug 2015 | Contributor(s):: Kenneth Ritchie
Bacteria, such as Escherichia coli and Caulobacter crescentus, are the most studied and perhaps best-understood organisms in biology. The advances in understanding of living systems gained from these organisms are immense....
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[Illinois] Knowledge, Context, and Process: Building a Foundational Infrastructure for Engineering Cells for Use in an Uncertain World
Online Presentations | 18 Aug 2015 | Contributor(s):: Adam Arkin
Both natural and synthetically augmented organisms, like those engineered to produce advanced biofuels, ultimately have to operate in an uncertain world. Resources change, contact with other life, and yield surprising interactions, and in some cases, changes in one’s own genetic code lead...
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Iterative Solution Method for an Implicit Orbit Averaged Particle-in-Cell Model
Online Presentations | 18 Aug 2015 | Contributor(s):: Benjamin Sturdevant
Present kinetic simulations of turbulence in magnetized plasmas employ models from gyrokinetic theory, which is based on a number of ordering assumptions used to reduce the Vlasov-Maxwell system to eliminate high frequency phenomena. Recently, a second order accurate, implicit particle-in-cell...
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[Illinois] Mechanical Design Considerations for Stretchable Cell Culture Systems
Online Presentations | 08 Aug 2014 | Contributor(s):: Chelsey Simmons
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[Illinois] Biomaterials to Replicate the Form and Function of Inhomogeneous Structures in the Body
Online Presentations | 28 Apr 2014 | Contributor(s):: Brendan Harley
The extracellular matrix (ECM) is a complex organization of structural proteins such as collagens and proteoglycans. Understanding that the ECM is dynamic and often spatially patterned or heterogeneous over the length-scale of traditional biomaterials, we are developing instructive biomaterials...
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[Illinois] Peptide Release from the Cells of the Dorsal Root Ganglion upon Application of Tensile Strain
Online Presentations | 04 Feb 2014 | Contributor(s):: Emily Tillmaand
Morphological and electrophysiological studies have shown that neurons respond to specific mechanical environments. However, studies linking specific neuropeptide release based on changes in the mechanical environment are lacking. To further study the effect of mechanical stress on the cells of...
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[Illinois] BioNanotechnology Seminar Series Fall 2011: Bio-inspired Microenvironments Regulate Cell Fate
Online Presentations | 14 Jun 2013 | Contributor(s):: Adam Engler
Epigenetic regulation of stem cell fate by intrinsic properties of the surrounding extracellular matrix (ECM), e.g. stiffness, organization, composition, etc., appears to be an important yet underappreciated contributor in development, disease, and aging. I will describe our efforts to develop...
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[Illinois] CMMB IGERT & M-CNTC Annual Symposium: Program Overview
Online Presentations | 06 Jun 2013 | Contributor(s):: Taher A. Saif
The second annual CMMB IGERT PI and Trainee Meeting was held on August 31, 2011. Dr. Saif walks through the goals and current status of the programs, and introduces the students involved.
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[Illinois] Bionanotechnology Seminar Series Fall 2012: Mechanical Property Characterization for 3D Collagen Cancer Cell Cultures
Online Presentations | 08 Mar 2013 | Contributor(s):: Yue Wang
The tumor microenvironment is mechanically modified during cancer progression. Imaging of tumor mechanical environment will provide new information for early cancer diagnosis. However, it is less clear how the mechanical environment is tuned in cancer. The goal of this study is to understand more...
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[Illinois] CPLC Seminar Series: Living Cell Studies Assisted by Nanoengineering Surfaces
Online Presentations | 26 Nov 2012 | Contributor(s):: Logan Liu
It is known that living cells interact with their micro and nanoscale environments. We created a variety of nanoengineered surfaces which can interact with living cells grown on top. Two particular examples will be demonstrated. The first one is ultrasensitive 3D confocal fluorescence microscopy...
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In Living Motion: Imaging Cellular Function in Live Tissues
Online Presentations | 21 Aug 2012 | Contributor(s):: David D. Nolte
Subcellular motions inside live tissue are sensitive indicators of cellular health and cellular response to applied drugs. Digital holography volumetrically captures these motions in tissue dynamics spectroscopy for live-tissue drug screening.
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Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy
Online Presentations | 05 Dec 2011 | Contributor(s):: Li Tang
Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer treatment. The size of these drug delivery vehicles has been strongly correlated with their in...
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Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements
Online Presentations | 05 Dec 2011 | Contributor(s):: Elise Corbin
The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through which a cell's physical properties influence cell growth, cell differentiation, cell cycle...
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BME 695L Special Lecture 4: Atomic Force Microscopy (AFM) for Nanomedical Systems (cells and nanoparticles)
Online Presentations | 02 Dec 2011 | Contributor(s):: Helen McNally
Guest lecturer: Helen McNally
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BME 695L Lecture 12: Assessing Drug Efficacy and Nanotoxicity at the Single Cell Level
Online Presentations | 22 Nov 2011 | Contributor(s):: James Leary
See references below for related reading.12.1 Introduction to measures of efficacy for nanomedicine12.1.1 for evaluation purposes, does structure/size reveal function?12.1.2 nanomedical treatment at the single cell...
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BME 695L Special Lecture 2: X-ray Photoelectron Spectroscopy (XPS) in Biologically-Relevant Applications
Online Presentations | 01 Nov 2011 | Contributor(s):: Dmitry Zemlyanov
Guest lecturer: Dmitry Zemlyanov
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BME 695L Lecture 11: Assessing Nanotoxicity at the Single Cell Level
Online Presentations | 27 Oct 2011 | Contributor(s):: James Leary
See references below for related reading.11.1 Need for single cell measures of nanotoxicity11.1.1 There is more than one way for a cell to die...11.1.2 "Necrosis" vs. "Apoptosis"11.1.3 There...
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Discussion about Ion Channels Using Reduced Model Approaches
Online Presentations | 21 Sep 2011 | Contributor(s):: James Fonseca
The seminar will cover the reasons how the channels are able to selectively permit the flow of certain species of ions while blocking other physiological cations.