3D CELL CULTURE
- Overview
- Members
- Announcements
- Blog
- Calendar
- Collections
- Forum
- Projects
- Resources
- Usage
- Wiki
- Wish List
- Citations
- Files
- Activity
resource/newsletterV8
Volume 8, February 2017
Newsletter
3D at Purdue
3D in Focus
3D in Publications
3D in Meetings
3D at Purdue
We are collaborating with Drs. Lelièvre and Kwok to develop novel methods to culture single rare cells in a manner that allows high throughout analysis and testing. We expect that these studies will enhance our understanding of heterogeneity and pave the way to personalized therapy.
Professor Çağrı A. Savran
School of Mechanical Engineering
School of Biomedical Engineering (by courtesy)
School of Electrical and Computer Engineering (by courtesy)
3D in Focus
Osteoarthritis is one of the leading causes of chronic disability for elderlies. One of the possible causes of the disease is synovial inflammation by macrophage activation. The objective of the article highlighted in this newsletter was to build and validate a 3D coculture system for osteoarthritis inflammation through paracrine interactions between chondrocytes and macrophages.
Featured article: Satyavrata Samavedi, Patricia Diaz-Rodriguez, Joshua D. Erndt-Marino, and Mariah S. Hahn. A Three-Dimensional Chondrocyte-Macrophage Coculture System to Probe Inflammation in Experimental Osteoarthritis Tissue. Tissue Engineering: Part A 2017, 23: 101-114.
In the transwell system, normal chondrocytes (NCs) cultured in the upper chamber and activated macrophages (AMs) cultured in the bottom chamber were both placed in a 3D environment by encapsulation within poly(ethylene glycol) diacrylate hydrogels. Increased levels of matrix metalloproteinases (MMPs) and proinflammatory cytokines that are associated with early stages of osteoarthritis were observed in NCs cells in the coculture system. Such increases were also detected in osteoarthritic chondrocytes (OACs) in coculture with AMs, although the levels of MMPs and proinflammatory cytokines were already enhanced in OACs due to the natural disease process. The OACs cultured in the presence of nonactivated macrophages demonstrated a lower increase in levels of MMPs and proinflammatory cytokines, indicating that AMs may intensify the abnormal matrix degradation and cytokine secretion in OACs. In addition, AMs cocultured with OACs expressed significantly more IL-1b and VEGF-A compared to AMs alone, suggesting that OACs may also intensify abnormal activation in macrophages.
Advantages of the proposed model: Despite the primary location of the macrophages in the knee joint within the synovial membrane, in the previously reported models of in vitro osteoarthritis, only the chondrocytes were cultured in a 3D microenvironment; the macrophages were cultured in 2D as a monolayer. The significance of the present model is to culture both chondrocytes and macrophages in a 3D environment. Moreover, the authors of the present report investigated the phenotypic changes in macrophages in coculture with chondrocytes; these cells have not been a focus of study in previous work dealing with osteoarthritis. Furthermore, the use of diseased rather than normal chondrocytes may enable the modeling of the later stages of osteoarthritis progression; this seems an appropriate model for testing potential therapeutic approaches of the disease.
Next possible steps: Osteoarthritis progression involves many steps and interactions among different cell types and extracellular matrices. The work in the highlighted article, however, examined only the interaction between chondrocytes and macrophages for synovial inflammation. Moreover, models that recapitulate various stages in osteoarthritis are still needed. This work shows like other models before that is possible to obtain interesting answers even when using cell types from two different species (human chondrocytes vs. mouse macrophages). Future studies using primary human macrophages in the coculture system will be important to confirm the interaction between chondrocytes and macrophages described here.
3D in Publications
Complete List -- 3D culture related articles on PubMed (last 2 months)
Reviews
Scaffold free/Scaffold
Organ/Tissue/Cell
Others
3D in Publications
Complete List
Abe, T., Ohuchida, K., Koikawa, K., Endo, S., Okumura, T., Sada, M., Horioka, K., Zheng, B., Moriyama, T., Nakata, K., et al. (2017). Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination. Int J Oncol 50, 457-467.
Adak, A., Das, G., Barman, S., Mohapatra, S., Bhunia, D., Jana, B., and Ghosh, S. (2017). Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug. ACS Appl Mater Interfaces 9, 5067-5076.
Adil, M. M., Rodrigues, G. M., Kulkarni, R. U., Rao, A. T., Chernavsky, N. E., Miller, E. W., and Schaffer, D. V. (2017). Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform. Sci Rep 7, 40573.
Akasov, R., Gileva, A., Zaytseva-Zotova, D., Burov, S., Chevalot, I., Guedon, E., and Markvicheva, E. (2017). 3D in vitro co-culture models based on normal cells and tumor spheroids formed by cyclic RGD-peptide induced cell self-assembly. Biotechnol Lett 39, 45-53.
Alessandri, K., Andrique, L., Feyeux, M., Bikfalvi, A., Nassoy, P., and Recher, G. (2017). All-in-one 3D printed microscopy chamber for multidimensional imaging, the UniverSlide. Sci Rep 7, 42378.
Alkhatib, R., Hilal-Alnaqbi, A., Naciri, M., Al-Majmaie, R., Saseedharan, P., Karam, S. M., and Al-Rubeai, M. (2017). 3D culture of mouse gastric stem cells using porous microcarriers. Front Biosci (Schol Ed) 9, 172-179.
Amoedo, N. D., Obre, E., and Rossignol, R. (2017). Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy. Biochim Biophys Acta.
Angiolini, V. A., Cruz, C. U., Lopez, M. L., Simon, L., and Matte, U. (2017). Alginate-embedded HuH-7 cells increase MMP-9 and reduce OCLN expression in vitro. Cancer Cell Int 17, 5.
Angioni, M. M., Bellofatto, K., Merlin, S., Menegon, S., Perra, A., Petrelli, A., Sulas, P., Giordano, S., Columbano, A., and Follenzi, A. (2017). A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis. Oncotarget.
Backer, A., Erhardt, O., Wietbrock, L., Schel, N., Goppert, B., Dirschka, M., Abaffy, P., Sollich, T., Cecilia, A., and Gruhl, F. J. (2017). Silk scaffolds connected with different naturally occurring biomaterials for prostate cancer cell cultivation in 3D. Biopolymers 107, 70-79.
Baek, S., Han, N. R., Yun, J. I., Hwang, J. Y., Kim, M., Park, C. K., Lee, E., and Lee, S. T. (2017). Effects of Culture Dimensions on Maintenance of Porcine Inner Cell Mass-Derived Cell Self-Renewal. Mol Cells.
Banaeiyan, A. A., Theobald, J., Paukstyte, J., Wolfl, S., Adiels, C. B., and Goksor, M. (2017). Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication 9, 015014.
Barr, S., Hill, E. W., and Bayat, A. (2017). Development, fabrication and evaluation of a novel biomimetic human breast tissue derived breast implant surface. Acta Biomater 49, 260-271.
Belli, V., Guarnieri, D., Biondi, M., Della Sala, F., and Netti, P. A. (2017). Dynamics of nanoparticle diffusion and uptake in three-dimensional cell cultures. Colloids Surf B Biointerfaces 149, 7-15.
Bendtsen, S. T., Quinnell, S. P., and Wei, M. (2017). Development of a novel alginate-polyvinyl alcohol-hydroxyapatite hydrogel for 3D bioprinting bone tissue engineered scaffolds. J Biomed Mater Res A.
Bianchi, V. J., Weber, J. F., Waldman, S. D., Backstein, D., and Kandel, R. A. (2017). Formation of Hyaline Cartilage Tissue by Passaged Human Osteoarthritic Chondrocytes. Tissue Eng Part A 23, 156-165.
Binner, M., Bray, L. J., Friedrichs, J., Freudenberg, U., Tsurkan, M. V., and Werner, C. (2017). Cell-instructive starPEG-heparin-collagen composite matrices. Acta Biomater.
Borovjagin, A. V., Ogle, B. M., Berry, J. L., and Zhang, J. (2017). From Microscale Devices to 3D Printing: Advances in Fabrication of 3D Cardiovascular Tissues. Circ Res 120, 150-165.
Bouchemi, M., Roubeix, C., Kessal, K., Riancho, L., Raveu, A. L., Soualmia, H., Baudouin, C., and Brignole-Baudouin, F. (2017). Effect of benzalkonium chloride on trabecular meshwork cells in a new in vitro 3D trabecular meshwork model for glaucoma. Toxicol In Vitro 41, 21-29.
Bouchet, B. P., and Akhmanova, A. (2017). Microtubules in 3D cell motility. J Cell Sci 130, 39-50.
Brancato, V., Comunanza, V., Imparato, G., Cora, D., Urciuolo, F., Noghero, A., Bussolino, F., and Netti, P. A. (2017). Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer. Acta Biomater 49, 152-166.
Burek, M., Waskiewicz, S., Lalik, A., Student, S., Bieg, T., and Wandzik, I. (2017). Thermoresponsive microgels containing trehalose as soft matrices for 3D cell culture. Biomater Sci 5, 234-246.
Cao, Y., Hjort, M., Chen, H., Birey, F., Leal-Ortiz, S. A., Han, C. M., Santiago, J. G., Pasca, S. P., Wu, J. C., and Melosh, N. A. (2017). Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring. Proc Natl Acad Sci U S A.
Capra, J. P., and Eskelinen, S. M. (2017). MDCK cells are capable of water secretion and reabsorption in response to changes in the ionic environment. Can J Physiol Pharmacol 95, 72-83.
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Cepeda, M. A., Evered, C. L., Pelling, J. J., and Damjanovski, S. (2017a). Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels. J Cell Commun Signal.
Cepeda, M. A., Pelling, J. J., Evered, C. L., Leong, H. S., and Damjanovski, S. (2017b). The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells. Exp Cell Res 350, 169-183.
Cevenini, L., Calabretta, M. M., Lopreside, A., Branchini, B. R., Southworth, T. L., Michelini, E., and Roda, A. (2017). Bioluminescence Imaging of Spheroids for High-throughput Longitudinal Studies on 3D Cell Culture Models. Photochem Photobiol.
Chacon-Martinez, C. A., Klose, M., Niemann, C., Glauche, I., and Wickstrom, S. A. (2017). Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny. Embo j 36, 151-164.
Chatzinikolaidou, M., Pontikoglou, C., Terzaki, K., Kaliva, M., Kalyva, A., Papadaki, E., Vamvakaki, M., and Farsari, M. (2017). Recombinant human bone morphogenetic protein 2 (rhBMP-2) immobilized on laser-fabricated 3D scaffolds enhance osteogenesis. Colloids Surf B Biointerfaces 149, 233-242.
Chen, G., Xu, R., Zhang, C., and Lv, Y. (2017). Responses of MSCs to 3D Scaffold Matrix Mechanical Properties under Oscillatory Perfusion Culture. ACS Appl Mater Interfaces 9, 1207-1218.
Cheong, J. G., Song, D. G., Song, H. E., Berditchevski, F., Nam, S. H., Jung, J. W., Kim, H. J., Kim, J. E., Kim, S., Ryu, J., et al. (2017). Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment. Oncotarget.
Chinnakkannu Vijayakumar, S., Venkatakrishnan, K., and Tan, B. (2017). SERS Active Nanobiosensor Functionalized by Self-Assembled 3D Nickel Nanonetworks for Glutathione Detection. ACS Appl Mater Interfaces.
Chioni, A. M., Bajwa, R. T., and Grose, R. (2017). 3D Organotypic Culture Model to Study Components of ERK Signaling. Methods Mol Biol 1487, 255-267.
Chitrangi, S., Nair, P., and Khanna, A. (2017). 3D engineered In vitro hepatospheroids for studying drug toxicity and metabolism. Toxicol In Vitro 38, 8-18.
Correia, C. R., Santos, T. C., Pirraco, R. P., Cerqueira, M. T., Marques, A. P., Reis, R. L., and Mano, J. F. (2017). In vivo osteogenic differentiation of stem cells inside compartmentalized capsules loaded with co-cultured endothelial cells. Acta Biomater.
DeCicco RePass, M. A., Chen, Y., Lin, Y., Zhou, W., Kaplan, D. L., and Ward, H. D. (2017). Novel Bioengineered Three-Dimensional Human Intestinal Model for Long-Term Infection of Cryptosporidium parvum. Infect Immun 85.
Di Federico, E., Shelton, J. C., and Bader, D. L. (2017). Complex mechanical conditioning of cell-seeded agarose constructs can influence chondrocyte biosynthetic activity. Biotechnol Bioeng.
Ding, H., Zhong, J., Xu, F., Song, F., Yin, M., Wu, Y., Hu, Q., and Wang, J. (2017). Establishment of 3D culture and induction of osteogenic differentiation of pre-osteoblasts using wet-collected aligned scaffolds. Mater Sci Eng C Mater Biol Appl 71, 222-230.
Dittmer, A., Woskobojnik, I., Adfeldt, R., Drach, J. C., Townsend, L. B., Voigt, S., and Bogner, E. (2017). Tetrahalogenated benzimidazole D-ribonucleosides are active against rat cytomegalovirus. Antiviral Res 137, 102-107.
do Nascimento Pedrosa, T., De Vuyst, E., Mound, A., Lambert de Rouvroit, C., Maria-Engler, S. S., and Poumay, Y. (2017). Methyl-beta-cyclodextrin treatment combined to incubation with interleukin-4 reproduces major features of atopic dermatitis in a 3D-culture model. Arch Dermatol Res 309, 63-69.
Dou, X. Q., and Feng, C. L. (2017). Amino Acids and Peptide-Based Supramolecular Hydrogels for Three-Dimensional Cell Culture. Adv Mater.
Drobnik, J., Pietrucha, K., Kudzin, M., Mader, K., Szymanski, J., and Szczepanowska, A. (2017). Comparison of various types of collagenous scaffolds applied for embryonic nerve cell culture. Biologicals.
Du, Y., Li, N., Yang, H., Luo, C., Gong, Y., Tong, C., Gao, Y., Lu, S., and Long, M. (2017). Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip. Lab Chip.
Edgar, J. M., Robinson, M., and Willerth, S. M. (2017). Fibrin hydrogels induce mixed dorsal/ventral spinal neuron identities during differentiation of human induced pluripotent stem cells. Acta Biomater.
Emmakah, A. M., Arman, H., Bragg, J., Greene, T., Alvarez, M., Childress, P., Goebel, W. S., Kacena, M., Lin, C. C., and Chu, T. M. (2017). A Fast-Degrading Thiol-Acrylate based Hydrogel for Cranial Regeneration. Biomed Mater.
Eyckmans, J., and Chen, C. S. (2017). 3D culture models of tissues under tension. J Cell Sci 130, 63-70.
Fan, C., and Wang, D. A. (2017). Macroporous Hydrogel Scaffolds for Three-Dimensional Cell Culture and Tissue Engineering. Tissue Eng Part B Rev.
Fang, Y., Wang, B., Zhao, Y., Xiao, Z., Li, J., Cui, Y., Han, S., Wei, J., Chen, B., Han, J., et al. (2017). Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells. Sci Rep 7, 42049.
Ferraz, M. A., Henning, H. H., Costa, P. F., Malda, J., Melchels, F. P., Wubbolts, R., Stout, T. A., Vos, P. L., and Gadella, B. M. (2017). Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation. Lab Chip.
Foster, J. W., Wahlin, K., Adams, S. M., Birk, D. E., Zack, D. J., and Chakravarti, S. (2017a). Cornea organoids from human induced pluripotent stem cells. Sci Rep 7, 41286.
Foster, M. W., Gwinn, W. M., Kelly, F. L., Brass, D. M., Valente, A. M., Moseley, M. A., Thompson, J. W., Morgan, D. L., and Palmer, S. M. (2017b). Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl. J Proteome Res 16, 538-549.
Franco-Barraza, J., Francescone, R., Luong, T., Shah, N., Madhani, R., Cukierman, G., Dulaimi, E., Devarajan, K., Egleston, B. L., Nicolas, E., et al. (2017). Matrix-regulated integrin alphavbeta5 maintains alpha5beta1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife 6.
Fremont, S., and Echard, A. (2017). Studying cytokinesis and midbody remnants using correlative light/scanning EM. Methods Cell Biol 137, 239-251.
Funk, C., and Roth, A. (2017). Current limitations and future opportunities for prediction of DILI from in vitro. Arch Toxicol 91, 131-142.
Fuzer, A. M., Lee, S. Y., Mott, J. D., and Cominetti, M. R. (2017). [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. J Cell Biochem.
Gajewska, M., and McNally, S. (2017). Using 3D Culture of Primary Mammary Epithelial Cells to Define Molecular Entities Required for Acinus Formation: Analyzing MAP Kinase Phosphatases. Methods Mol Biol 1501, 199-216.
Galuppo, A. G., Chagastelles, P. C., Gamba, D., Iglesias, D. B., Sperling, L. E., Machado, J., Petry, J. F., Wendorff, J., Petzhold, C. L., and Pranke, P. (2017). Effect of feeder free poly(lactide-co-glycolide) scaffolds on morphology, proliferation, and pluripotency of mouse embryonic stem cells. J Biomed Mater Res A 105, 424-432.
Ganesan, M. K., Finsterwalder, R., Leb, H., Resch, U., Neumuller, K., de Martin, R., and Petzelbauer, P. (2017). Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells. Tissue Eng Part C Methods 23, 38-49.
Gao, G., Zhang, X. F., Hubbell, K., and Cui, X. (2017a). NR2F2 regulates chondrogenesis of human mesenchymal stem cells in bioprinted cartilage. Biotechnol Bioeng 114, 208-216.
Gao, J., Tang, C., Elsawy, M. A., Smith, A. M., Miller, A. F., and Saiani, A. (2017b). Controlling Self-Assembling Peptide Hydrogel Properties through Network Topology. Biomacromolecules.
Gao, Q., Wang, Z. C., Duan, M., Lin, Y. H., Zhou, X. Y., Worthley, D. L., Wang, X. Y., Niu, G., Xia, Y., Deng, M., et al. (2017c). Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. Gastroenterology 152, 232-242.e234.
Gao, X. L., Wu, J. S., Cao, M. X., Gao, S. Y., Cen, X., Jiang, Y. P., Wang, S. S., Tang, Y. J., Chen, Q. M., Liang, X. H., and Tang, Y. (2017d). Cytokeratin-14 contributes to collective invasion of salivary adenoid cystic carcinoma. PLoS One 12, e0171341.
Gawri, R., Shiba, T., Pilliar, R., and Kandel, R. (2017). Inorganic polyphosphates enhances nucleus pulposus tissue formation in vitro. J Orthop Res 35, 41-50.
Ghezzi, C. E., Marelli, B., Omenetto, F. G., Funderburgh, J. L., and Kaplan, D. L. (2017). 3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture. PLoS One 12, e0169504.
Ghobeira, R., Philips, C., Declercq, H., Cools, P., De Geyter, N., Cornelissen, R., and Morent, R. (2017). Effects of different sterilization methods on the physico-chemical and bioresponsive properties of plasma-treated polycaprolactone films. Biomed Mater 12, 015017.
Gimenez, A., Uriarte, J. J., Vieyra, J., Navajas, D., and Alcaraz, J. (2017). Elastic properties of hydrogels and decellularized tissue sections used in mechanobiology studies probed by atomic force microscopy. Microsc Res Tech 80, 85-96.
Gwon, K., Kim, E., and Tae, G. (2017). Heparin-hyaluronic acid hydrogel in support of cellular activities of 3D encapsulated adipose derived stem cells. Acta Biomater 49, 284-295.
Halfter, K., and Mayer, B. (2017). Bringing 3D tumor models to the clinic - predictive value for personalized medicine. Biotechnol J.
He, X., and Toth, T. L. (2017). In vitro culture of ovarian follicles from Peromyscus. Semin Cell Dev Biol 61, 140-149.
Henriksson, I., Gatenholm, P., and Hagg, D. A. (2017). Increased lipid accumulation and adipogenic gene expression of adipocytes in 3D bioprinted nanocellulose scaffolds. Biofabrication 9, 015022.
Hernandez-Fernaud, J. R., Ruengeler, E., Casazza, A., Neilson, L. J., Pulleine, E., Santi, A., Ismail, S., Lilla, S., Dhayade, S., MacPherson, I. R., et al. (2017). Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nat Commun 8, 14206.
Hogrebe, N. J., Reinhardt, J. W., and Gooch, K. J. (2017). Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization. J Biomed Mater Res A 105, 640-661.
Holmes, D. B., and Heine, V. M. (2017). Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open.
Homma, K., Usui, S., and Kaneda, M. (2017). Knock-in strategy at 3'-end of Crx gene by CRISPR/Cas9 system shows the gene expression profiles during human photoreceptor differentiation. Genes Cells.
Houshmand, M., Soleimani, M., Atashi, A., Saglio, G., Abdollahi, M., and Nikougoftar Zarif, M. (2017). Mimicking the Acute Myeloid Leukemia Niche for Molecular Study and Drug Screening. Tissue Eng Part C Methods.
Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J., and Chidgey, A. P. (2017). Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation. Biomaterials 118, 1-15.
Hunt, N. C., Hallam, D., Karimi, A., Mellough, C. B., Chen, J., Steel, D. H., and Lako, M. (2017). 3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development. Acta Biomater 49, 329-343.
Ibrahim, M., and Richardson, M. K. (2017). In vitro development of zebrafish vascular networks. Reprod Toxicol.
Imig, C., and Cooper, B. H. (2017). 3D Analysis of Synaptic Ultrastructure in Organotypic Hippocampal Slice Culture by High-Pressure Freezing and Electron Tomography. Methods Mol Biol 1538, 215-231.
Ishida, M., Marubashi, S., and Fukuda, M. (2017). M-INK, a novel tool for visualizing melanosomes and melanocores. J Biochem.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Ivanov, D. P., and Grabowska, A. M. (2017). Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D. Sci Rep 7, 41160.
Jakobsson, A., Ottosson, M., Zalis, M. C., O'Carroll, D., Johansson, U. E., and Johansson, F. (2017). Three-dimensional functional human neuronal networks in uncompressed low-density electrospun fiber scaffolds. Nanomedicine.
Jeon, H., Kang, K., Park, S. A., Kim, W. D., Paik, S. S., Lee, S. H., Jeong, J., and Choi, D. (2017). Generation of Multilayered 3D Structures of HepG2 Cells Using a Bio-printing Technique. Gut Liver 11, 121-128.
Jeon, S. J., and Hayward, R. C. (2017). Reconfigurable Microscale Frameworks from Concatenated Helices with Controlled Chirality. Adv Mater.
Ji, J., Hedelin, A., Malmlof, M., Kessler, V., Seisenbaeva, G., Gerde, P., and Palmberg, L. (2017). Development of Combining of Human Bronchial Mucosa Models with XposeALI(R) for Exposure of Air Pollution Nanoparticles. PLoS One 12, e0170428.
Jiang, R. D., Lin, H., Zheng, G., Zhang, X. M., Du, Q., and Yang, M. (2017). In vitro dentin barrier cytotoxicity testing of some dental restorative materials. J Dent.
Jorgens, D. M., Inman, J. L., Wojcik, M., Robertson, C., Palsdottir, H., Tsai, W. T., Huang, H., Bruni-Cardoso, A., Lopez, C. S., Bissell, M. J., et al. (2017). Deep nuclear invaginations are linked to cytoskeletal filaments - integrated bioimaging of epithelial cells in 3D culture. J Cell Sci 130, 177-189.
Kaisar, M. A., Sajja, R. K., Prasad, S., Abhyankar, V. V., Liles, T., and Cucullo, L. (2017). New experimental models of the blood-brain barrier for CNS drug discovery. Expert Opin Drug Discov 12, 89-103.
Kasper, A. M., Turner, D. C., Martin, N. R., and Sharples, A. P. (2017). Mimicking Exercise in Three-Dimensional Bioengineered Skeletal Muscle to Investigate Cellular and Molecular Mechanisms of Physiological Adaptation. J Cell Physiol.
Kaynak Bayrak, G., Demirtas, T. T., and Gumusderelioglu, M. (2017). Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds. Carbohydr Polym 157, 803-813.
Kim, H. J., Kwon, S., Nam, S. H., Jung, J. W., Kang, M., Ryu, J., Kim, J. E., Cheong, J. G., Cho, C. Y., Kim, S., et al. (2017). Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments. Faseb j.
Knight, V. B., and Serrano, E. E. (2017). Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PeerJ 5, e2829.
Koivisto, J. T., Joki, T., Parraga, J., Paakkonen, R., Yla-Outinen, L., Salonen, L., Jonkkari, I., Peltola, M., Ihalainen, T., Narkilahti, S., and Kellomaki, M. (2017). Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering. Biomed Mater.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Koshkin, V., Ailles, L. E., Liu, G., and Krylov, S. N. (2017). Preservation of the 3D Phenotype Upon Dispersal of Cultured Cell Spheroids Into Monolayer Cultures. J Cell Biochem 118, 154-162.
Kostrzewski, T., Cornforth, T., Snow, S. A., Ouro-Gnao, L., Rowe, C., Large, E. M., and Hughes, D. J. (2017). Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease. World J Gastroenterol 23, 204-215.
Koumarianou, P., Gomez-Lopez, G., and Santisteban, P. (2017). Pax8 controls thyroid follicular polarity through cadherin-16. J Cell Sci 130, 219-231.
Kremer, A., Ribitsch, I., Reboredo, J., Durr, J., Egerbacher, M., Jenner, F., and Walles, H. (2017). 3D co-culture of meniscal cells and mesenchymal stem cells in collagen type I hydrogel on a small intestinal matrix - a pilot study towards equine meniscus tissue engineering. Tissue Eng Part A.
Kuznetsova, A. V., and Aleksandrova, M. A. (2017). Heterogeneity of Retinal Pigment Epithelial Cells from Adult Human Eye in Different Culturing Systems. Bull Exp Biol Med.
Lakner, P. H., Monaghan, M. G., Moller, Y., Olayioye, M. A., and Schenke-Layland, K. (2017). Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models. Sci Rep 7, 42730.
Laschke, M. W., and Menger, M. D. (2017). Life is 3D: Boosting Spheroid Function for Tissue Engineering. Trends Biotechnol 35, 133-144.
Leclerc, E., Kimura, K., Shinohara, M., Danoy, M., Le Gall, M., Kido, T., Miyajima, A., Fujii, T., and Sakai, Y. (2017). Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment. Genomics 109, 16-26.
Lee, J., Kim, H. J., and Yi, J. Y. (2017a). A secretome analysis reveals that PPARalpha is upregulated by fractionated-dose gamma-irradiation in three-dimensional keratinocyte cultures. Biochem Biophys Res Commun 482, 270-276.
Lee, J. A., Kim, M. K., Song, J. H., Jo, M. R., Yu, J., Kim, K. M., Kim, Y. R., Oh, J. M., and Choi, S. J. (2017b). Biokinetics of food additive silica nanoparticles and their interactions with food components. Colloids Surf B Biointerfaces 150, 384-392.
Li, L., Chen, J., Xiong, G., St Clair, D. K., Xu, W., and Xu, R. (2017a). Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. J Cell Sci 130, 190-202.
Li, L. M., Han, M., Jiang, X. C., Yin, X. Z., Chen, F., Zhang, T. Y., Ren, H., Zhang, J. W., Hou, T. J., Chen, Z., et al. (2017b). Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells. ACS Appl Mater Interfaces 9, 3330-3342.
Li, L. M., Han, M., Jiang, X. C., Yin, X. Z., Chen, F., Zhang, T. Y., Ren, H., Zhang, J. W., Hou, T. J., Chen, Z., et al. (2017c). Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells. ACS Appl Mater Interfaces.
Li, M., Nagamori, E., and Kino-Oka, M. (2017d). Disruption of myoblast alignment by highly motile rhabdomyosarcoma cell in tissue structure. J Biosci Bioeng 123, 259-264.
Li, R., Hebert, J. D., Lee, T. A., Xing, H., Boussommier-Calleja, A., Hynes, R. O., Lauffenburger, D. A., and Kamm, R. D. (2017e). Macrophage-Secreted TNFalpha and TGFbeta1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. Cancer Res 77, 279-290.
Li, X., Brooks, J. C., Hu, J., Ford, K. I., and Easley, C. J. (2017f). 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17, 341-349.
Li, Y., He, L., Pan, S., Zhang, L., Zhang, W., Yi, H., and Niu, Y. (2017g). Three-dimensional simulated microgravity culture improves the proliferation and odontogenic differentiation of dental pulp stem cell in PLGA scaffolds implanted in mice. Mol Med Rep 15, 873-878.
Li, Y., Wu, Q., Wang, Y., Li, L., Chen, F., Shi, Y., Bao, J., and Bu, H. (2017h). Construction of bioengineered hepatic tissue derived from human umbilical cord mesenchymal stem cells via aggregation culture in porcine decellularized liver scaffolds. Xenotransplantation.
Li, Y., Wu, Q., Wang, Y., Li, L., Chen, F., Shi, Y., Bu, H., and Bao, J. (2017i). Immunogenicity of hepatic differentiated human umbilical cord mesenchymal stem cells promoted by porcine decellularized liver scaffolds. Xenotransplantation.
Li, Y., Zhang, Y., Shi, F., Tao, L., Wei, Y., and Wang, X. (2017j). Modulus-regulated 3D-cell proliferation in an injectable self-healing hydrogel. Colloids Surf B Biointerfaces 149, 168-173.
Liang, J., Susan Sun, X., Yang, Z., and Cao, S. (2017). Anticancer Drug Camptothecin Test in 3D Hydrogel Networks with HeLa cells. Sci Rep 7, 37626.
Liau, B., Jackman, C. P., Li, Y., and Bursac, N. (2017). Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. Sci Rep 7, 42290.
Lienemann, P. S., Rossow, T., Mao, A. S., Vallmajo-Martin, Q., Ehrbar, M., and Mooney, D. J. (2017). Single cell-laden protease-sensitive microniches for long-term culture in 3D. Lab Chip 17, 727-737.
Link, P. A., Pouliot, R. A., Mikhaiel, N. S., Young, B. M., and Heise, R. L. (2017). Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture. J Vis Exp.
Lintz, M., Munoz, A., and Reinhart-King, C. A. (2017). The Mechanics of Single Cell and Collective Migration of Tumor Cells. J Biomech Eng 139.
Liu, J., Liu, K., Feng, L., Liu, Z., and Xu, L. (2017). Comparison of nanomedicine-based chemotherapy, photodynamic therapy and photothermal therapy using reduced graphene oxide for the model system. Biomater Sci 5, 331-340.
Liverani, C., La Manna, F., Groenewoud, A., Mercatali, L., Van Der Pluijm, G., Pieri, F., Cavaliere, D., De Vita, A., Spadazzi, C., Miserocchi, G., et al. (2017). Innovative approaches to establish and characterize primary cultures: an ex vivo 3D system and the zebrafish model. Biol Open 6, 133-140.
Luckert, C., Schulz, C., Lehmann, N., Thomas, M., Hofmann, U., Hammad, S., Hengstler, J. G., Braeuning, A., Lampen, A., and Hessel, S. (2017). Comparative analysis of 3D culture methods on human HepG2 cells. Arch Toxicol 91, 393-406.
Luo, D., Guan, Q., Wang, K., Nguan, C. Y., and Du, C. (2017). TGF-beta1 stimulates movement of renal proximal tubular epithelial cells in a three-dimensional cell culture via an autocrine TGF-beta2 production. Exp Cell Res 350, 132-139.
Madl, C. M., and Heilshorn, S. C. (2017). Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels. Bioconjug Chem.
Martinez de Pinillos Bayona, A., Woodhams, J. H., Pye, H., Hamoudi, R. A., Moore, C. M., and MacRobert, A. J. (2017). Efficacy of photochemical internalisation using disulfonated chlorin and porphyrin photosensitisers: an in vitro study in 2D and 3D prostate cancer models. Cancer Lett.
Middendorf, J. M., Griffin, D. J., Shortkroff, S., Dugopolski, C., Kennedy, S., Siemiatkoski, J., Cohen, I., and Bonassar, L. J. (2017). Mechanical properties and structure-function relationships of human chondrocyte-seeded cartilage constructs after in vitro culture. J Orthop Res.
Miguel, J. C., Maxwell, A. A., Hsieh, J. J., Harnisch, L. C., Al Alam, D., Polk, D. B., Lien, C. L., Watson, A. J., and Frey, M. R. (2017). Epidermal growth factor suppresses intestinal epithelial cell shedding through a MAPK-dependent pathway. J Cell Sci 130, 90-96.
Moghadam, M. Z., Hassanajili, S., Esmaeilzadeh, F., Ayatollahi, M., and Ahmadi, M. (2017). Formation of porous HPCL/LPCL/HA scaffolds with supercritical CO2 gas foaming method. J Mech Behav Biomed Mater 69, 115-127.
Morselli, M. G., Canziani, S., Vigo, D., and Luvoni, G. C. (2017). A three-dimensional alginate system for in vitro culture of cumulus-denuded feline oocytes. Reprod Domest Anim 52, 83-88.
Nakamachi, E., Noma, T., Nakahara, K., Tomita, Y., and Morita, Y. (2017). Multi-Photon Microscope Measurement Based Biphasic Multi-Scale Analyses of Knee Joint Articular Cartilage and Chondrocyte by Using Visco-Anisotropic Hyperelastic Finite Element Method and Smoothed Particle Hydrodynamics Method. Int J Numer Method Biomed Eng.
Nakamura, T., Takagi, S., Kamon, T., Yamasaki, K. I., and Fujisato, T. (2017). Development and evaluation of a removable tissue-engineered muscle with artificial tendons. J Biosci Bioeng 123, 265-271.
Nakaoka, T., Saito, Y., Shimamoto, Y., Muramatsu, T., Kimura, M., Kanai, Y., and Saito, H. (2017). The cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids. Cancer Sci.
Nguyen, D. T., van Noort, D., Jeong, I. K., and Park, S. (2017). Endocrine system on chip for a diabetes treatment model. Biofabrication 9, 015021.
Nie, J., and Hashino, E. (2017). Organoid technologies meet genome engineering. EMBO Rep.
Nih, L. R., Moshayedi, P., Llorente, I. L., Berg, A. R., Cinkornpumin, J., Lowry, W. E., Segura, T., and Carmichael, S. T. (2017). Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief 10, 202-209.
Nikravesh, N., Cox, S. C., Birdi, G., Williams, R. L., and Grover, L. M. (2017). Calcium pre-conditioning substitution enhances viability and glucose sensitivity of pancreatic beta-cells encapsulated using polyelectrolyte multilayer coating method. Sci Rep 7, 43171.
Novikov, I. A., Vakhrushev, I. V., Antonov, E. N., Yarygin, K. N., and Subbot, A. M. (2017). Visualization of Mesenchymal Stromal Cells in 2Dand 3D-Cultures by Scanning Electron Microscopy with Lanthanide Contrasting. Bull Exp Biol Med.
Nowak, M., Freudenberg, U., Tsurkan, M. V., Werner, C., and Levental, K. R. (2017). Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Biomaterials 112, 20-30.
Nune, K. C., Kumar, A., Misra, R. D., Li, S. J., Hao, Y. L., and Yang, R. (2017). Functional response of osteoblasts in functionally gradient titanium alloy mesh arrays processed by 3D additive manufacturing. Colloids Surf B Biointerfaces 150, 78-88.
Odenwald, M. A., Choi, W., Buckley, A., Shashikanth, N., Joseph, N. E., Wang, Y., Warren, M. H., Buschmann, M. M., Pavlyuk, R., Hildebrand, J., et al. (2017). ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. J Cell Sci 130, 243-259.
Ouyang, A., Cerchiari, A. E., Tang, X., Liebenberg, E., Alliston, T., Gartner, Z. J., and Lotz, J. C. (2017). Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells. J Orthop Res 35, 61-73.
Pagano, F., Angelini, F., Siciliano, C., Tasciotti, J., Mangino, G., De Falco, E., Carnevale, R., Sciarretta, S., Frati, G., and Chimenti, I. (2017). Beta2-adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation. Pharmacol Res.
Paino, F., La Noce, M., Giuliani, A., De Rosa, A., Mazzoni, S., Laino, L., Amler, E., Papaccio, G., Desiderio, V., and Tirino, V. (2017). hDPSCs fabricate a vascularised woven bone tissue: a new tool in bone tissue engineering. Clin Sci (Lond).
Pamies, D., and Hartung, T. (2017). 21st Century Cell Culture for 21st Century Toxicology. Chem Res Toxicol 30, 43-52.
Park, J., Lee, S. J., Chung, S., Lee, J. H., Kim, W. D., Lee, J. Y., and Park, S. A. (2017). Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation. Mater Sci Eng C Mater Biol Appl 71, 678-684.
Parreno, J., Nabavi Niaki, M., Andrejevic, K., Jiang, A., Wu, P. H., and Kandel, R. A. (2017). Interplay between cytoskeletal polymerization and the chondrogenic phenotype in chondrocytes passaged in monolayer culture. J Anat 230, 234-248.
Partyka, P. P., Godsey, G. A., Galie, J. R., Kosciuk, M. C., Acharya, N. K., Nagele, R. G., and Galie, P. A. (2017). Mechanical stress regulates transport in a compliant 3D model of the blood-brain barrier. Biomaterials 115, 30-39.
Pecci-Lloret, M. P., Vera-Sanchez, M., Aznar-Cervantes, S., Garcia-Bernal, D., Sanchez, R. O., Pecci-Lloret, M. R., Moraleda, J. M., Cenis, J. L., and Rodriguez-Lozano, F. J. (2017). Analysis of the Adherence of Dental Pulp Stem Cells on Two-Dimensional and Three-Dimensional Silk Fibroin-Based Biomaterials: Applications in Regenerative Dentistry. J Craniofac Surg.
Penfornis, P., Vallabhaneni, K. C., Janorkar, A. V., and Pochampally, R. R. (2017). Three dimensional tumor models for cancer studies. Front Biosci (Elite Ed) 9, 162-173.
Perez White, B. E., Ventrella, R., Kaplan, N., Cable, C. J., Thomas, P. M., and Getsios, S. (2017). EphA2 proteomics in human keratinocytes reveals a novel association with afadin and epidermal tight junctions. J Cell Sci 130, 111-118.
Perin, N., Bobanovic, K., Zlatar, I., Jelic, D., Kelava, V., Kostrun, S., Markovic, V. G., Brajsa, K., and Hranjec, M. (2017). Antiproliferative activity of amino substituted benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles explored by 2D and 3D cell culture system. Eur J Med Chem 125, 722-735.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Piotrowski-Daspit, A. S., Simi, A. K., Pang, M. F., Tien, J., and Nelson, C. M. (2017). A 3D Culture Model to Study How Fluid Pressure and Flow Affect the Behavior of Aggregates of Epithelial Cells. Methods Mol Biol 1501, 245-257.
Pompaiah, M., and Bartfeld, S. (2017). Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis. Curr Top Microbiol Immunol 400, 149-168.
Pradhan, S., Clary, J. M., Seliktar, D., and Lipke, E. A. (2017a). A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres. Biomaterials 115, 141-154.
Pradhan, S., Hassani, I., Seeto, W. J., and Lipke, E. A. (2017b). PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture. J Biomed Mater Res A 105, 236-252.
Qu, Y., Han, B., Gao, B., Bose, S., Gong, Y., Wawrowsky, K., Giuliano, A. E., Sareen, D., and Cui, X. (2017). Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports 8, 205-215.
Regmi, S., Cao, J., Pathak, S., Gupta, B., Kumar Poudel, B., Tung, P. T., Yook, S., Park, J. B., Yong, C. S., Kim, J. O., et al. (2017). A three-dimensional assemblage of gingiva-derived mesenchymal stem cells and NO-releasing microspheres for improved differentiation. Int J Pharm 520, 163-172.
Riedl, A., Schlederer, M., Pudelko, K., Stadler, M., Walter, S., Unterleuthner, D., Unger, C., Kramer, N., Hengstschlager, M., Kenner, L., et al. (2017). Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses. J Cell Sci 130, 203-218.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Ruprecht, V., Monzo, P., Ravasio, A., Yue, Z., Makhija, E., Strale, P. O., Gauthier, N., Shivashankar, G. V., Studer, V., Albiges-Rizo, C., and Viasnoff, V. (2017). How cells respond to environmental cues - insights from bio-functionalized substrates. J Cell Sci 130, 51-61.
Russell, M. R., Lerner, T. R., Burden, J. J., Nkwe, D. O., Pelchen-Matthews, A., Domart, M. C., Durgan, J., Weston, A., Jones, M. L., Peddie, C. J., et al. (2017). 3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy. J Cell Sci 130, 278-291.
Saito, Y., Nakaoka, T., and Saito, H. (2017). A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response. Adv Protein Chem Struct Biol 106, 227-242.
Samavedi, S., Diaz-Rodriguez, P., Erndt-Marino, J. D., and Hahn, M. S. (2017). A Three-Dimensional Chondrocyte-Macrophage Coculture System to Probe Inflammation in Experimental Osteoarthritis. Tissue Eng Part A 23, 101-114.
Sandstrom, J., Eggermann, E., Charvet, I., Roux, A., Toni, N., Greggio, C., Broyer, A., Monnet-Tschudi, F., and Stoppini, L. (2017). Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing. Toxicol In Vitro 38, 124-135.
Santo, V. E., Rebelo, S. P., Estrada, M. F., Alves, P. M., Boghaert, E., and Brito, C. (2017). Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J 12.
Sato, E., Williams, M. R., Sanford, J. A., Sen, G. L., Nakama, T., Imafuku, S., and Gallo, R. L. (2017). The parathyroid hormone family member TIP39 interacts with sarco/endoplasmic reticulum Ca2+ - ATPase activity by influencing calcium homeostasis. Exp Dermatol.
Schneeberger, K., Spee, B., Costa, P., Sachs, N., Clevers, H., and Malda, J. (2017). Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? Biofabrication.
Seo, C. H., Kwack, M. H., Kim, M. K., Kim, J. C., and Sung, Y. K. (2017). Activin A-induced signalling controls hair follicle neogenesis. Exp Dermatol 26, 108-115.
Shannon, S., Jia, D., Entersz, I., Beelen, P., Yu, M., Carcione, C., Carcione, J., Mahtabfar, A., Vaca, C., Weaver, M., et al. (2017). Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901. BMC Cancer 17, 121.
Short, A. R., Czeisler, C., Stocker, B., Cole, S., Otero, J. J., and Winter, J. O. (2017). Imaging Cell-Matrix Interactions in 3D Collagen Hydrogel Culture Systems. Macromol Biosci.
Shukla, M. R., Singh, A. S., Piunno, K., Saxena, P. K., and Jones, A. M. (2017). Application of 3D printing to prototype and develop novel plant tissue culture systems. Plant Methods 13, 6.
Shumilova, A. A., Myltygashev, M. P., Kirichenko, A. K., Nikolaeva, E. D., Volova, T. G., and Shishatskaya, E. I. (2017). Porous 3D implants of degradable poly-3-hydroxybutyrate used to enhance regeneration of rat cranial defect. J Biomed Mater Res A 105, 566-577.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Sisakhtnezhad, S., Alimoradi, E., and Akrami, H. (2017). External factors influencing mesenchymal stem cell fate in vitro. Eur J Cell Biol 96, 13-33.
Sittadjody, S., Saul, J. M., and Opara, E. C. (2017). Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules. Methods Mol Biol 1479, 225-235.
Spencer, K. C., Sy, J. C., Falcon-Banchs, R., and Cima, M. J. (2017). A three dimensional in vitro glial scar model to investigate the local strain effects from micromotion around neural implants. Lab Chip.
Strobel, H. A., Dikina, A. D., Levi, K., Solorio, L. D., Alsberg, E., and Rolle, M. W. (2017). Cellular Self-Assembly with Microsphere Incorporation for Growth Factor Delivery Within Engineered Vascular Tissue Rings. Tissue Eng Part A 23, 143-155.
Szebeni, G. J., Tancos, Z., Feher, L. Z., Alfoldi, R., Kobolak, J., Dinnyes, A., and Puskas, L. G. (2017). Real architecture For 3D Tissue (RAFT) culture system improves viability and maintains insulin and glucagon production of mouse pancreatic islet cells. Cytotechnology.
Tan, Q., Choi, K. M., Sicard, D., and Tschumperlin, D. J. (2017). Human airway organoid engineering as a step toward lung regeneration and disease modeling. Biomaterials 113, 118-132.
Tang, X., Wang, X., Zhao, Y. Y., Curtis, J. M., and Brindley, D. N. (2017). Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-kappaB activation. Mol Cancer 16, 36.
Tanimizu, N., and Mitaka, T. (2017). Epithelial Morphogenesis during Liver Development. Cold Spring Harb Perspect Biol.
Terrasso, A. P., Silva, A. C., Filipe, A., Pedroso, P., Ferreira, A. L., Alves, P. M., and Brito, C. (2017). Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds. J Pharmacol Toxicol Methods 83, 72-79.
Thon, J. N., Dykstra, B. J., and Beaulieu, L. M. (2017). Platelet bioreactor: accelerated evolution of design and manufacture. Platelets, 1-6.
Tian, X., Brookes, O., and Battaglia, G. (2017). Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier. Sci Rep 7, 39676.
Tokuda, E. Y., Jones, C. E., and Anseth, K. S. (2017). PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity. Integr Biol (Camb) 9, 76-87.
Totti, S., Vernardis, S. I., Meira, L., Perez-Mancera, P. A., Costello, E., Greenhalf, W., Palmer, D., Neoptolemos, J., Mantalaris, A., and Velliou, E. G. (2017). Designing a bio-inspired biomimetic in vitro system for the optimization of ex vivo studies of pancreatic cancer. Drug Discov Today.
Ukaji, T., Lin, Y., Okada, S., and Umezawa, K. (2017). Inhibition of MMP-2-mediated cellular invasion by NF-kappaB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis. Biochem Biophys Res Commun.
Uz, M., Buyukoz, M., Sharma, A. D., Sakaguchi, D. S., Altinkaya, S. A., and Mallapragada, S. K. (2017). Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes. Acta Biomater.
Vagaska, B., and Ferretti, P. (2017). Toward modeling the human nervous system in a dish: recent progress and outstanding challenges. Regen Med 12, 15-23.
van den Brand, D., Massuger, L. F., Brock, R., and Verdurmen, W. P. (2017). Mimicking Tumors: Towards More Predictive In Vitro Models for Peptide- and Protein-Conjugated Drugs. Bioconjug Chem.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Vidal-Quadras, M., Holst, M. R., Francis, M. K., Larsson, E., Hachimi, M., Yau, W. L., Peranen, J., Martin-Belmonte, F., and Lundmark, R. (2017). Endocytic turnover of Rab8 controls cell polarization. J Cell Sci.
Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C., and Cress, A. E. (2017a). A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci 130, 104-110.
Wang, S., Ghezzi, C. E., Gomes, R., Pollard, R. E., Funderburgh, J. L., and Kaplan, D. L. (2017b). In vitro 3D corneal tissue model with epithelium, stroma, and innervation. Biomaterials 112, 1-9.
Weisblum, Y., Oiknine-Djian, E., Vorontsov, O. M., Haimov-Kochman, R., Zakay-Rones, Z., Meir, K., Shveiky, D., Elgavish, S., Nevo, Y., Roseman, M., et al. (2017a). Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal Interface. J Virol 91.
Weisblum, Y., Oiknine-Djian, E., Vorontsov, O. M., Haimov-Kochman, R., Zakay-Rones, Z., Meir, K., Shveiky, D., Elgavish, S., Nevo, Y., Roseman, M., et al. (2017b). Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal Interface. J Virol 91.
Weltin, A., Hammer, S., Noor, F., Kaminski, Y., Kieninger, J., and Urban, G. A. (2017). Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Biosens Bioelectron 87, 941-948.
Xue, C., Xie, J., Zhao, D., Lin, S., Zhou, T., Shi, S., Shao, X., Lin, Y., Zhu, B., and Cai, X. (2017). The JAK/STAT3 signalling pathway regulated angiogenesis in an endothelial cell/adipose-derived stromal cell co-culture, 3D gel model. Cell Prolif 50.
Yang, G., Long, H., Ren, X., Ma, K., Xiao, Z., Wang, Y., and Guo, Y. (2017a). Regulation of adipose-tissue-derived stromal cell orientation and motility in 2D- and 3D-cultures by direct-current electrical field. Dev Growth Differ.
Yang, J., Chen, X., Yuan, T., Yang, X., Fan, Y., and Zhang, X. (2017b). Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis. Mater Sci Eng C Mater Biol Appl 70, 983-991.
Yang, J. P., Anderson, A. E., McCartney, A., Ory, X., Ma, G., Pappalardo, E., Bader, J., and Elisseeff, J. (2017c). Metabolically active 3-dimensional brown adipose tissue engineered from white adipose-derived stem cells. Tissue Eng Part A.
Ye, X., Li, S., Chen, X., Zhan, Y., and Li, X. (2017). Polyethylenimine/silk fibroin multilayers deposited nanofibrics for cell culture. Int J Biol Macromol 94, 492-499.
Yildiz-Ozturk, E., Gulce-Iz, S., Anil, M., and Yesil-Celiktas, O. (2017). Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture. Cytotechnology.
Zhang, F., Wang, L., Li, Y., Liu, W., Duan, F., Huang, R., Chen, X., Chang, S. C., Du, Y., and Na, J. (2017a). Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells. Stem Cell Res Ther 8, 6.
Zhang, W., Lee, W. Y., and Zilberberg, J. (2017b). Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma. Methods Mol Biol 1513, 171-191.
Zhao, Y., Qiao, S., Shi, S., Yao, L., Hou, X., Li, C., Lin, F. H., Guo, K., Acharya, A., Chen, X., et al. (2017). Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS Appl Mater Interfaces.
Zheng, Z., Ran, J., Chen, W., Hu, Y., Zhu, T., Chen, X., Yin, Z., Heng, B. C., Feng, G., Le, H., et al. (2017). Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair. Acta Biomater.
Zhou, Z., Yi, Q., Xia, T., Yin, W., Kadi, A. A., Li, J., and Zhang, Y. (2017). A photo-degradable supramolecular hydrogel for selective delivery of microRNA into 3D-cultured cells. Org Biomol Chem.
Zhu, Z., and Yang, C. J. (2017). Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis. Acc Chem Res 50, 22-31.
Zuchowska, A., Kwapiszewska, K., Chudy, M., Dybko, A., and Brzozka, Z. (2017). Studies of anticancer drug cytotoxicity based on long-term HepG2 spheroid culture in a microfluidic system. Electrophoresis.
Reviews
Amoedo, N. D., Obre, E., and Rossignol, R. (2017). Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy. Biochim Biophys Acta.
Borovjagin, A. V., Ogle, B. M., Berry, J. L., and Zhang, J. (2017). From Microscale Devices to 3D Printing: Advances in Fabrication of 3D Cardiovascular Tissues. Circ Res 120, 150-165.
Bouchet, B. P., and Akhmanova, A. (2017). Microtubules in 3D cell motility. J Cell Sci 130, 39-50.
Dou, X. Q., and Feng, C. L. (2017). Amino Acids and Peptide-Based Supramolecular Hydrogels for Three-Dimensional Cell Culture. Adv Mater.
Eyckmans, J., and Chen, C. S. (2017). 3D culture models of tissues under tension. J Cell Sci 130, 63-70.
Fan, C., and Wang, D. A. (2017). Macroporous Hydrogel Scaffolds for Three-Dimensional Cell Culture and Tissue Engineering. Tissue Eng Part B Rev.
Funk, C., and Roth, A. (2017). Current limitations and future opportunities for prediction of DILI from in vitro. Arch Toxicol 91, 131-142.
Gimenez, A., Uriarte, J. J., Vieyra, J., Navajas, D., and Alcaraz, J. (2017). Elastic properties of hydrogels and decellularized tissue sections used in mechanobiology studies probed by atomic force microscopy. Microsc Res Tech 80, 85-96.
Halfter, K., and Mayer, B. (2017). Bringing 3D tumor models to the clinic - predictive value for personalized medicine. Biotechnol J.
He, X., and Toth, T. L. (2017). In vitro culture of ovarian follicles from Peromyscus. Semin Cell Dev Biol 61, 140-149.
Hogrebe, N. J., Reinhardt, J. W., and Gooch, K. J. (2017). Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization. J Biomed Mater Res A 105, 640-661.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Kaisar, M. A., Sajja, R. K., Prasad, S., Abhyankar, V. V., Liles, T., and Cucullo, L. (2017). New experimental models of the blood-brain barrier for CNS drug discovery. Expert Opin Drug Discov 12, 89-103.
Kasper, A. M., Turner, D. C., Martin, N. R., and Sharples, A. P. (2017). Mimicking Exercise in Three-Dimensional Bioengineered Skeletal Muscle to Investigate Cellular and Molecular Mechanisms of Physiological Adaptation. J Cell Physiol.
Laschke, M. W., and Menger, M. D. (2017). Life is 3D: Boosting Spheroid Function for Tissue Engineering. Trends Biotechnol 35, 133-144.
Lintz, M., Munoz, A., and Reinhart-King, C. A. (2017). The Mechanics of Single Cell and Collective Migration of Tumor Cells. J Biomech Eng 139.
Nie, J., and Hashino, E. (2017). Organoid technologies meet genome engineering. EMBO Rep.
Penfornis, P., Vallabhaneni, K. C., Janorkar, A. V., and Pochampally, R. R. (2017). Three dimensional tumor models for cancer studies. Front Biosci (Elite Ed) 9, 162-173.
Pompaiah, M., and Bartfeld, S. (2017). Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis. Curr Top Microbiol Immunol 400, 149-168.
Ruprecht, V., Monzo, P., Ravasio, A., Yue, Z., Makhija, E., Strale, P. O., Gauthier, N., Shivashankar, G. V., Studer, V., Albiges-Rizo, C., and Viasnoff, V. (2017). How cells respond to environmental cues - insights from bio-functionalized substrates. J Cell Sci 130, 51-61.
Santo, V. E., Rebelo, S. P., Estrada, M. F., Alves, P. M., Boghaert, E., and Brito, C. (2017). Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J 12.
Schneeberger, K., Spee, B., Costa, P., Sachs, N., Clevers, H., and Malda, J. (2017). Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? Biofabrication.
Sisakhtnezhad, S., Alimoradi, E., and Akrami, H. (2017). External factors influencing mesenchymal stem cell fate in vitro. Eur J Cell Biol 96, 13-33.
Thon, J. N., Dykstra, B. J., and Beaulieu, L. M. (2017). Platelet bioreactor: accelerated evolution of design and manufacture. Platelets, 1-6.
Totti, S., Vernardis, S. I., Meira, L., Perez-Mancera, P. A., Costello, E., Greenhalf, W., Palmer, D., Neoptolemos, J., Mantalaris, A., and Velliou, E. G. (2017). Designing a bio-inspired biomimetic in vitro system for the optimization of ex vivo studies of pancreatic cancer. Drug Discov Today.
Vagaska, B., and Ferretti, P. (2017). Toward modeling the human nervous system in a dish: recent progress and outstanding challenges. Regen Med 12, 15-23.
van den Brand, D., Massuger, L. F., Brock, R., and Verdurmen, W. P. (2017). Mimicking Tumors: Towards More Predictive In Vitro Models for Peptide- and Protein-Conjugated Drugs. Bioconjug Chem.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Zhu, Z., and Yang, C. J. (2017). Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis. Acc Chem Res 50, 22-31.
Spheroids
Adak, A., Das, G., Barman, S., Mohapatra, S., Bhunia, D., Jana, B., and Ghosh, S. (2017). Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug. ACS Appl Mater Interfaces 9, 5067-5076.
Backer, A., Erhardt, O., Wietbrock, L., Schel, N., Goppert, B., Dirschka, M., Abaffy, P., Sollich, T., Cecilia, A., and Gruhl, F. J. (2017). Silk scaffolds connected with different naturally occurring biomaterials for prostate cancer cell cultivation in 3D. Biopolymers 107, 70-79.
Holmes, D. B., and Heine, V. M. (2017). Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Ivanov, D. P., and Grabowska, A. M. (2017). Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D. Sci Rep 7, 41160.
Kim, H. J., Kwon, S., Nam, S. H., Jung, J. W., Kang, M., Ryu, J., Kim, J. E., Cheong, J. G., Cho, C. Y., Kim, S., et al. (2017). Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments. Faseb j.
Koshkin, V., Ailles, L. E., Liu, G., and Krylov, S. N. (2017). Preservation of the 3D Phenotype Upon Dispersal of Cultured Cell Spheroids Into Monolayer Cultures. J Cell Biochem 118, 154-162.
Kuznetsova, A. V., and Aleksandrova, M. A. (2017). Heterogeneity of Retinal Pigment Epithelial Cells from Adult Human Eye in Different Culturing Systems. Bull Exp Biol Med.
Laschke, M. W., and Menger, M. D. (2017). Life is 3D: Boosting Spheroid Function for Tissue Engineering. Trends Biotechnol 35, 133-144.
Liu, J., Liu, K., Feng, L., Liu, Z., and Xu, L. (2017). Comparison of nanomedicine-based chemotherapy, photodynamic therapy and photothermal therapy using reduced graphene oxide for the model system. Biomater Sci 5, 331-340.
Nikravesh, N., Cox, S. C., Birdi, G., Williams, R. L., and Grover, L. M. (2017). Calcium pre-conditioning substitution enhances viability and glucose sensitivity of pancreatic beta-cells encapsulated using polyelectrolyte multilayer coating method. Sci Rep 7, 43171.
Ouyang, A., Cerchiari, A. E., Tang, X., Liebenberg, E., Alliston, T., Gartner, Z. J., and Lotz, J. C. (2017). Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells. J Orthop Res 35, 61-73.
Pradhan, S., Clary, J. M., Seliktar, D., and Lipke, E. A. (2017). A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres. Biomaterials 115, 141-154.
Riedl, A., Schlederer, M., Pudelko, K., Stadler, M., Walter, S., Unterleuthner, D., Unger, C., Kramer, N., Hengstschlager, M., Kenner, L., et al. (2017). Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses. J Cell Sci 130, 203-218.
Shannon, S., Jia, D., Entersz, I., Beelen, P., Yu, M., Carcione, C., Carcione, J., Mahtabfar, A., Vaca, C., Weaver, M., et al. (2017). Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901. BMC Cancer 17, 121.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Szebeni, G. J., Tancos, Z., Feher, L. Z., Alfoldi, R., Kobolak, J., Dinnyes, A., and Puskas, L. G. (2017). Real architecture For 3D Tissue (RAFT) culture system improves viability and maintains insulin and glucagon production of mouse pancreatic islet cells. Cytotechnology.
Ukaji, T., Lin, Y., Okada, S., and Umezawa, K. (2017). Inhibition of MMP-2-mediated cellular invasion by NF-kappaB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis. Biochem Biophys Res Commun.
Weltin, A., Hammer, S., Noor, F., Kaminski, Y., Kieninger, J., and Urban, G. A. (2017). Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Biosens Bioelectron 87, 941-948.
Zhao, Y., Qiao, S., Shi, S., Yao, L., Hou, X., Li, C., Lin, F. H., Guo, K., Acharya, A., Chen, X., et al. (2017). Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS Appl Mater Interfaces.
Zuchowska, A., Kwapiszewska, K., Chudy, M., Dybko, A., and Brzozka, Z. (2017). Studies of anticancer drug cytotoxicity based on long-term HepG2 spheroid culture in a microfluidic system. Electrophoresis.
Organoid
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Chioni, A. M., Bajwa, R. T., and Grose, R. (2017). 3D Organotypic Culture Model to Study Components of ERK Signaling. Methods Mol Biol 1487, 255-267.
Foster, J. W., Wahlin, K., Adams, S. M., Birk, D. E., Zack, D. J., and Chakravarti, S. (2017). Cornea organoids from human induced pluripotent stem cells. Sci Rep 7, 41286.
Holmes, D. B., and Heine, V. M. (2017). Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open.
Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J., and Chidgey, A. P. (2017). Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation. Biomaterials 118, 1-15.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Nakaoka, T., Saito, Y., Shimamoto, Y., Muramatsu, T., Kimura, M., Kanai, Y., and Saito, H. (2017). The cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids. Cancer Sci.
Nie, J., and Hashino, E. (2017). Organoid technologies meet genome engineering. EMBO Rep.
Nowak, M., Freudenberg, U., Tsurkan, M. V., Werner, C., and Levental, K. R. (2017). Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Biomaterials 112, 20-30.
Pompaiah, M., and Bartfeld, S. (2017). Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis. Curr Top Microbiol Immunol 400, 149-168.
Qu, Y., Han, B., Gao, B., Bose, S., Gong, Y., Wawrowsky, K., Giuliano, A. E., Sareen, D., and Cui, X. (2017). Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports 8, 205-215.
Saito, Y., Nakaoka, T., and Saito, H. (2017). A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response. Adv Protein Chem Struct Biol 106, 227-242.
Schneeberger, K., Spee, B., Costa, P., Sachs, N., Clevers, H., and Malda, J. (2017). Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? Biofabrication.
Tan, Q., Choi, K. M., Sicard, D., and Tschumperlin, D. J. (2017). Human airway organoid engineering as a step toward lung regeneration and disease modeling. Biomaterials 113, 118-132.
Scaffold
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Chioni, A. M., Bajwa, R. T., and Grose, R. (2017). 3D Organotypic Culture Model to Study Components of ERK Signaling. Methods Mol Biol 1487, 255-267.
Foster, J. W., Wahlin, K., Adams, S. M., Birk, D. E., Zack, D. J., and Chakravarti, S. (2017). Cornea organoids from human induced pluripotent stem cells. Sci Rep 7, 41286.
Holmes, D. B., and Heine, V. M. (2017). Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open.
Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J., and Chidgey, A. P. (2017). Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation. Biomaterials 118, 1-15.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Nakaoka, T., Saito, Y., Shimamoto, Y., Muramatsu, T., Kimura, M., Kanai, Y., and Saito, H. (2017). The cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids. Cancer Sci.
Nie, J., and Hashino, E. (2017). Organoid technologies meet genome engineering. EMBO Rep.
Nowak, M., Freudenberg, U., Tsurkan, M. V., Werner, C., and Levental, K. R. (2017). Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Biomaterials 112, 20-30.
Pompaiah, M., and Bartfeld, S. (2017). Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis. Curr Top Microbiol Immunol 400, 149-168.
Qu, Y., Han, B., Gao, B., Bose, S., Gong, Y., Wawrowsky, K., Giuliano, A. E., Sareen, D., and Cui, X. (2017). Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports 8, 205-215.
Saito, Y., Nakaoka, T., and Saito, H. (2017). A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response. Adv Protein Chem Struct Biol 106, 227-242.
Schneeberger, K., Spee, B., Costa, P., Sachs, N., Clevers, H., and Malda, J. (2017). Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? Biofabrication.
Tan, Q., Choi, K. M., Sicard, D., and Tschumperlin, D. J. (2017). Human airway organoid engineering as a step toward lung regeneration and disease modeling. Biomaterials 113, 118-132.
Hydrogel
Adak, A., Das, G., Barman, S., Mohapatra, S., Bhunia, D., Jana, B., and Ghosh, S. (2017). Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug. ACS Appl Mater Interfaces 9, 5067-5076.
Adil, M. M., Rodrigues, G. M., Kulkarni, R. U., Rao, A. T., Chernavsky, N. E., Miller, E. W., and Schaffer, D. V. (2017). Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform. Sci Rep 7, 40573.
Alessandri, K., Andrique, L., Feyeux, M., Bikfalvi, A., Nassoy, P., and Recher, G. (2017). All-in-one 3D printed microscopy chamber for multidimensional imaging, the UniverSlide. Sci Rep 7, 42378.
Angiolini, V. A., Cruz, C. U., Lopez, M. L., Simon, L., and Matte, U. (2017). Alginate-embedded HuH-7 cells increase MMP-9 and reduce OCLN expression in vitro. Cancer Cell Int 17, 5.
Baek, S., Han, N. R., Yun, J. I., Hwang, J. Y., Kim, M., Park, C. K., Lee, E., and Lee, S. T. (2017). Effects of Culture Dimensions on Maintenance of Porcine Inner Cell Mass-Derived Cell Self-Renewal. Mol Cells.
Bendtsen, S. T., Quinnell, S. P., and Wei, M. (2017). Development of a novel alginate-polyvinyl alcohol-hydroxyapatite hydrogel for 3D bioprinting bone tissue engineered scaffolds. J Biomed Mater Res A.
Binner, M., Bray, L. J., Friedrichs, J., Freudenberg, U., Tsurkan, M. V., and Werner, C. (2017). Cell-instructive starPEG-heparin-collagen composite matrices. Acta Biomater.
Burek, M., Waskiewicz, S., Lalik, A., Student, S., Bieg, T., and Wandzik, I. (2017). Thermoresponsive microgels containing trehalose as soft matrices for 3D cell culture. Biomater Sci 5, 234-246.
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Ding, H., Zhong, J., Xu, F., Song, F., Yin, M., Wu, Y., Hu, Q., and Wang, J. (2017). Establishment of 3D culture and induction of osteogenic differentiation of pre-osteoblasts using wet-collected aligned scaffolds. Mater Sci Eng C Mater Biol Appl 71, 222-230.
Dou, X. Q., and Feng, C. L. (2017). Amino Acids and Peptide-Based Supramolecular Hydrogels for Three-Dimensional Cell Culture. Adv Mater.
Edgar, J. M., Robinson, M., and Willerth, S. M. (2017). Fibrin hydrogels induce mixed dorsal/ventral spinal neuron identities during differentiation of human induced pluripotent stem cells. Acta Biomater.
Emmakah, A. M., Arman, H., Bragg, J., Greene, T., Alvarez, M., Childress, P., Goebel, W. S., Kacena, M., Lin, C. C., and Chu, T. M. (2017). A Fast-Degrading Thiol-Acrylate based Hydrogel for Cranial Regeneration. Biomed Mater.
Fan, C., and Wang, D. A. (2017). Macroporous Hydrogel Scaffolds for Three-Dimensional Cell Culture and Tissue Engineering. Tissue Eng Part B Rev.
Gao, J., Tang, C., Elsawy, M. A., Smith, A. M., Miller, A. F., and Saiani, A. (2017). Controlling Self-Assembling Peptide Hydrogel Properties through Network Topology. Biomacromolecules.
Gwon, K., Kim, E., and Tae, G. (2017). Heparin-hyaluronic acid hydrogel in support of cellular activities of 3D encapsulated adipose derived stem cells. Acta Biomater 49, 284-295.
Hunt, N. C., Hallam, D., Karimi, A., Mellough, C. B., Chen, J., Steel, D. H., and Lako, M. (2017). 3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development. Acta Biomater 49, 329-343.
Ibrahim, M., and Richardson, M. K. (2017). In vitro development of zebrafish vascular networks. Reprod Toxicol.
Jeon, S. J., and Hayward, R. C. (2017). Reconfigurable Microscale Frameworks from Concatenated Helices with Controlled Chirality. Adv Mater.
Kaynak Bayrak, G., Demirtas, T. T., and Gumusderelioglu, M. (2017). Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds. Carbohydr Polym 157, 803-813.
Knight, V. B., and Serrano, E. E. (2017). Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PeerJ 5, e2829.
Koivisto, J. T., Joki, T., Parraga, J., Paakkonen, R., Yla-Outinen, L., Salonen, L., Jonkkari, I., Peltola, M., Ihalainen, T., Narkilahti, S., and Kellomaki, M. (2017). Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering. Biomed Mater.
Kremer, A., Ribitsch, I., Reboredo, J., Durr, J., Egerbacher, M., Jenner, F., and Walles, H. (2017). 3D co-culture of meniscal cells and mesenchymal stem cells in collagen type I hydrogel on a small intestinal matrix - a pilot study towards equine meniscus tissue engineering. Tissue Eng Part A.
Li, L. M., Han, M., Jiang, X. C., Yin, X. Z., Chen, F., Zhang, T. Y., Ren, H., Zhang, J. W., Hou, T. J., Chen, Z., et al. (2017a). Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells. ACS Appl Mater Interfaces 9, 3330-3342.
Li, L. M., Han, M., Jiang, X. C., Yin, X. Z., Chen, F., Zhang, T. Y., Ren, H., Zhang, J. W., Hou, T. J., Chen, Z., et al. (2017b). Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells. ACS Appl Mater Interfaces.
Li, Y., Zhang, Y., Shi, F., Tao, L., Wei, Y., and Wang, X. (2017c). Modulus-regulated 3D-cell proliferation in an injectable self-healing hydrogel. Colloids Surf B Biointerfaces 149, 168-173.
Liang, J., Susan Sun, X., Yang, Z., and Cao, S. (2017). Anticancer Drug Camptothecin Test in 3D Hydrogel Networks with HeLa cells. Sci Rep 7, 37626.
Liau, B., Jackman, C. P., Li, Y., and Bursac, N. (2017). Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. Sci Rep 7, 42290.
Lienemann, P. S., Rossow, T., Mao, A. S., Vallmajo-Martin, Q., Ehrbar, M., and Mooney, D. J. (2017). Single cell-laden protease-sensitive microniches for long-term culture in 3D. Lab Chip 17, 727-737.
Link, P. A., Pouliot, R. A., Mikhaiel, N. S., Young, B. M., and Heise, R. L. (2017). Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture. J Vis Exp.
Madl, C. M., and Heilshorn, S. C. (2017). Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels. Bioconjug Chem.
Martinez de Pinillos Bayona, A., Woodhams, J. H., Pye, H., Hamoudi, R. A., Moore, C. M., and MacRobert, A. J. (2017). Efficacy of photochemical internalisation using disulfonated chlorin and porphyrin photosensitisers: an in vitro study in 2D and 3D prostate cancer models. Cancer Lett.
Morselli, M. G., Canziani, S., Vigo, D., and Luvoni, G. C. (2017). A three-dimensional alginate system for in vitro culture of cumulus-denuded feline oocytes. Reprod Domest Anim 52, 83-88.
Nih, L. R., Moshayedi, P., Llorente, I. L., Berg, A. R., Cinkornpumin, J., Lowry, W. E., Segura, T., and Carmichael, S. T. (2017). Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief 10, 202-209.
Nowak, M., Freudenberg, U., Tsurkan, M. V., Werner, C., and Levental, K. R. (2017). Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Biomaterials 112, 20-30.
Park, J., Lee, S. J., Chung, S., Lee, J. H., Kim, W. D., Lee, J. Y., and Park, S. A. (2017). Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation. Mater Sci Eng C Mater Biol Appl 71, 678-684.
Pradhan, S., Clary, J. M., Seliktar, D., and Lipke, E. A. (2017a). A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres. Biomaterials 115, 141-154.
Pradhan, S., Hassani, I., Seeto, W. J., and Lipke, E. A. (2017b). PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture. J Biomed Mater Res A 105, 236-252.
Short, A. R., Czeisler, C., Stocker, B., Cole, S., Otero, J. J., and Winter, J. O. (2017). Imaging Cell-Matrix Interactions in 3D Collagen Hydrogel Culture Systems. Macromol Biosci.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Sittadjody, S., Saul, J. M., and Opara, E. C. (2017). Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules. Methods Mol Biol 1479, 225-235.
Tanimizu, N., and Mitaka, T. (2017). Epithelial Morphogenesis during Liver Development. Cold Spring Harb Perspect Biol.
Terrasso, A. P., Silva, A. C., Filipe, A., Pedroso, P., Ferreira, A. L., Alves, P. M., and Brito, C. (2017). Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds. J Pharmacol Toxicol Methods 83, 72-79.
Tokuda, E. Y., Jones, C. E., and Anseth, K. S. (2017). PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity. Integr Biol (Camb) 9, 76-87.
Zhao, Y., Qiao, S., Shi, S., Yao, L., Hou, X., Li, C., Lin, F. H., Guo, K., Acharya, A., Chen, X., et al. (2017). Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS Appl Mater Interfaces.
Zhou, Z., Yi, Q., Xia, T., Yin, W., Kadi, A. A., Li, J., and Zhang, Y. (2017). A photo-degradable supramolecular hydrogel for selective delivery of microRNA into 3D-cultured cells. Org Biomol Chem.
Zhu, Z., and Yang, C. J. (2017). Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis. Acc Chem Res 50, 22-31.
Matrix
Alkhatib, R., Hilal-Alnaqbi, A., Naciri, M., Al-Majmaie, R., Saseedharan, P., Karam, S. M., and Al-Rubeai, M. (2017). 3D culture of mouse gastric stem cells using porous microcarriers. Front Biosci (Schol Ed) 9, 172-179.
Angiolini, V. A., Cruz, C. U., Lopez, M. L., Simon, L., and Matte, U. (2017). Alginate-embedded HuH-7 cells increase MMP-9 and reduce OCLN expression in vitro. Cancer Cell Int 17, 5.
Backer, A., Erhardt, O., Wietbrock, L., Schel, N., Goppert, B., Dirschka, M., Abaffy, P., Sollich, T., Cecilia, A., and Gruhl, F. J. (2017). Silk scaffolds connected with different naturally occurring biomaterials for prostate cancer cell cultivation in 3D. Biopolymers 107, 70-79.
Baek, S., Han, N. R., Yun, J. I., Hwang, J. Y., Kim, M., Park, C. K., Lee, E., and Lee, S. T. (2017). Effects of Culture Dimensions on Maintenance of Porcine Inner Cell Mass-Derived Cell Self-Renewal. Mol Cells.
Belli, V., Guarnieri, D., Biondi, M., Della Sala, F., and Netti, P. A. (2017). Dynamics of nanoparticle diffusion and uptake in three-dimensional cell cultures. Colloids Surf B Biointerfaces 149, 7-15.
Binner, M., Bray, L. J., Friedrichs, J., Freudenberg, U., Tsurkan, M. V., and Werner, C. (2017). Cell-instructive starPEG-heparin-collagen composite matrices. Acta Biomater.
Bouchemi, M., Roubeix, C., Kessal, K., Riancho, L., Raveu, A. L., Soualmia, H., Baudouin, C., and Brignole-Baudouin, F. (2017). Effect of benzalkonium chloride on trabecular meshwork cells in a new in vitro 3D trabecular meshwork model for glaucoma. Toxicol In Vitro 41, 21-29.
Bouchet, B. P., and Akhmanova, A. (2017). Microtubules in 3D cell motility. J Cell Sci 130, 39-50.
Brancato, V., Comunanza, V., Imparato, G., Cora, D., Urciuolo, F., Noghero, A., Bussolino, F., and Netti, P. A. (2017). Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer. Acta Biomater 49, 152-166.
Burek, M., Waskiewicz, S., Lalik, A., Student, S., Bieg, T., and Wandzik, I. (2017). Thermoresponsive microgels containing trehalose as soft matrices for 3D cell culture. Biomater Sci 5, 234-246.
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Cepeda, M. A., Evered, C. L., Pelling, J. J., and Damjanovski, S. (2017a). Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels. J Cell Commun Signal.
Cepeda, M. A., Pelling, J. J., Evered, C. L., Leong, H. S., and Damjanovski, S. (2017b). The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells. Exp Cell Res 350, 169-183.
Cevenini, L., Calabretta, M. M., Lopreside, A., Branchini, B. R., Southworth, T. L., Michelini, E., and Roda, A. (2017). Bioluminescence Imaging of Spheroids for High-throughput Longitudinal Studies on 3D Cell Culture Models. Photochem Photobiol.
Chacon-Martinez, C. A., Klose, M., Niemann, C., Glauche, I., and Wickstrom, S. A. (2017). Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny. Embo j 36, 151-164.
Chatzinikolaidou, M., Pontikoglou, C., Terzaki, K., Kaliva, M., Kalyva, A., Papadaki, E., Vamvakaki, M., and Farsari, M. (2017). Recombinant human bone morphogenetic protein 2 (rhBMP-2) immobilized on laser-fabricated 3D scaffolds enhance osteogenesis. Colloids Surf B Biointerfaces 149, 233-242.
Chen, G., Xu, R., Zhang, C., and Lv, Y. (2017). Responses of MSCs to 3D Scaffold Matrix Mechanical Properties under Oscillatory Perfusion Culture. ACS Appl Mater Interfaces 9, 1207-1218.
Dittmer, A., Woskobojnik, I., Adfeldt, R., Drach, J. C., Townsend, L. B., Voigt, S., and Bogner, E. (2017). Tetrahalogenated benzimidazole D-ribonucleosides are active against rat cytomegalovirus. Antiviral Res 137, 102-107.
Dou, X. Q., and Feng, C. L. (2017). Amino Acids and Peptide-Based Supramolecular Hydrogels for Three-Dimensional Cell Culture. Adv Mater.
Eyckmans, J., and Chen, C. S. (2017). 3D culture models of tissues under tension. J Cell Sci 130, 63-70.
Fan, C., and Wang, D. A. (2017). Macroporous Hydrogel Scaffolds for Three-Dimensional Cell Culture and Tissue Engineering. Tissue Eng Part B Rev.
Foster, J. W., Wahlin, K., Adams, S. M., Birk, D. E., Zack, D. J., and Chakravarti, S. (2017). Cornea organoids from human induced pluripotent stem cells. Sci Rep 7, 41286.
Franco-Barraza, J., Francescone, R., Luong, T., Shah, N., Madhani, R., Cukierman, G., Dulaimi, E., Devarajan, K., Egleston, B. L., Nicolas, E., et al. (2017). Matrix-regulated integrin alphavbeta5 maintains alpha5beta1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife 6.
Fuzer, A. M., Lee, S. Y., Mott, J. D., and Cominetti, M. R. (2017). [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. J Cell Biochem.
Gajewska, M., and McNally, S. (2017). Using 3D Culture of Primary Mammary Epithelial Cells to Define Molecular Entities Required for Acinus Formation: Analyzing MAP Kinase Phosphatases. Methods Mol Biol 1501, 199-216.
Ganesan, M. K., Finsterwalder, R., Leb, H., Resch, U., Neumuller, K., de Martin, R., and Petzelbauer, P. (2017). Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells. Tissue Eng Part C Methods 23, 38-49.
Gawri, R., Shiba, T., Pilliar, R., and Kandel, R. (2017). Inorganic polyphosphates enhances nucleus pulposus tissue formation in vitro. J Orthop Res 35, 41-50.
Ghezzi, C. E., Marelli, B., Omenetto, F. G., Funderburgh, J. L., and Kaplan, D. L. (2017). 3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture. PLoS One 12, e0169504.
Gimenez, A., Uriarte, J. J., Vieyra, J., Navajas, D., and Alcaraz, J. (2017). Elastic properties of hydrogels and decellularized tissue sections used in mechanobiology studies probed by atomic force microscopy. Microsc Res Tech 80, 85-96.
Gwon, K., Kim, E., and Tae, G. (2017). Heparin-hyaluronic acid hydrogel in support of cellular activities of 3D encapsulated adipose derived stem cells. Acta Biomater 49, 284-295.
He, X., and Toth, T. L. (2017). In vitro culture of ovarian follicles from Peromyscus. Semin Cell Dev Biol 61, 140-149.
Hogrebe, N. J., Reinhardt, J. W., and Gooch, K. J. (2017). Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization. J Biomed Mater Res A 105, 640-661.
Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J., and Chidgey, A. P. (2017). Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation. Biomaterials 118, 1-15.
Ibrahim, M., and Richardson, M. K. (2017). In vitro development of zebrafish vascular networks. Reprod Toxicol.
Jorgens, D. M., Inman, J. L., Wojcik, M., Robertson, C., Palsdottir, H., Tsai, W. T., Huang, H., Bruni-Cardoso, A., Lopez, C. S., Bissell, M. J., et al. (2017). Deep nuclear invaginations are linked to cytoskeletal filaments - integrated bioimaging of epithelial cells in 3D culture. J Cell Sci 130, 177-189.
Kaynak Bayrak, G., Demirtas, T. T., and Gumusderelioglu, M. (2017). Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds. Carbohydr Polym 157, 803-813.
Knight, V. B., and Serrano, E. E. (2017). Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PeerJ 5, e2829.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Koumarianou, P., Gomez-Lopez, G., and Santisteban, P. (2017). Pax8 controls thyroid follicular polarity through cadherin-16. J Cell Sci 130, 219-231.
Kremer, A., Ribitsch, I., Reboredo, J., Durr, J., Egerbacher, M., Jenner, F., and Walles, H. (2017). 3D co-culture of meniscal cells and mesenchymal stem cells in collagen type I hydrogel on a small intestinal matrix - a pilot study towards equine meniscus tissue engineering. Tissue Eng Part A.
Kuznetsova, A. V., and Aleksandrova, M. A. (2017). Heterogeneity of Retinal Pigment Epithelial Cells from Adult Human Eye in Different Culturing Systems. Bull Exp Biol Med.
Li, R., Hebert, J. D., Lee, T. A., Xing, H., Boussommier-Calleja, A., Hynes, R. O., Lauffenburger, D. A., and Kamm, R. D. (2017). Macrophage-Secreted TNFalpha and TGFbeta1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. Cancer Res 77, 279-290.
Liang, J., Susan Sun, X., Yang, Z., and Cao, S. (2017). Anticancer Drug Camptothecin Test in 3D Hydrogel Networks with HeLa cells. Sci Rep 7, 37626.
Link, P. A., Pouliot, R. A., Mikhaiel, N. S., Young, B. M., and Heise, R. L. (2017). Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture. J Vis Exp.
Madl, C. M., and Heilshorn, S. C. (2017). Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels. Bioconjug Chem.
Moghadam, M. Z., Hassanajili, S., Esmaeilzadeh, F., Ayatollahi, M., and Ahmadi, M. (2017). Formation of porous HPCL/LPCL/HA scaffolds with supercritical CO2 gas foaming method. J Mech Behav Biomed Mater 69, 115-127.
Nih, L. R., Moshayedi, P., Llorente, I. L., Berg, A. R., Cinkornpumin, J., Lowry, W. E., Segura, T., and Carmichael, S. T. (2017). Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief 10, 202-209.
Novikov, I. A., Vakhrushev, I. V., Antonov, E. N., Yarygin, K. N., and Subbot, A. M. (2017). Visualization of Mesenchymal Stromal Cells in 2Dand 3D-Cultures by Scanning Electron Microscopy with Lanthanide Contrasting. Bull Exp Biol Med.
Nowak, M., Freudenberg, U., Tsurkan, M. V., Werner, C., and Levental, K. R. (2017). Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Biomaterials 112, 20-30.
Nune, K. C., Kumar, A., Misra, R. D., Li, S. J., Hao, Y. L., and Yang, R. (2017). Functional response of osteoblasts in functionally gradient titanium alloy mesh arrays processed by 3D additive manufacturing. Colloids Surf B Biointerfaces 150, 78-88.
Odenwald, M. A., Choi, W., Buckley, A., Shashikanth, N., Joseph, N. E., Wang, Y., Warren, M. H., Buschmann, M. M., Pavlyuk, R., Hildebrand, J., et al. (2017). ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. J Cell Sci 130, 243-259.
Park, J., Lee, S. J., Chung, S., Lee, J. H., Kim, W. D., Lee, J. Y., and Park, S. A. (2017). Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation. Mater Sci Eng C Mater Biol Appl 71, 678-684.
Parreno, J., Nabavi Niaki, M., Andrejevic, K., Jiang, A., Wu, P. H., and Kandel, R. A. (2017). Interplay between cytoskeletal polymerization and the chondrogenic phenotype in chondrocytes passaged in monolayer culture. J Anat 230, 234-248.
Partyka, P. P., Godsey, G. A., Galie, J. R., Kosciuk, M. C., Acharya, N. K., Nagele, R. G., and Galie, P. A. (2017). Mechanical stress regulates transport in a compliant 3D model of the blood-brain barrier. Biomaterials 115, 30-39.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Pradhan, S., Clary, J. M., Seliktar, D., and Lipke, E. A. (2017a). A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres. Biomaterials 115, 141-154.
Pradhan, S., Hassani, I., Seeto, W. J., and Lipke, E. A. (2017b). PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture. J Biomed Mater Res A 105, 236-252.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Ruprecht, V., Monzo, P., Ravasio, A., Yue, Z., Makhija, E., Strale, P. O., Gauthier, N., Shivashankar, G. V., Studer, V., Albiges-Rizo, C., and Viasnoff, V. (2017). How cells respond to environmental cues - insights from bio-functionalized substrates. J Cell Sci 130, 51-61.
Samavedi, S., Diaz-Rodriguez, P., Erndt-Marino, J. D., and Hahn, M. S. (2017). A Three-Dimensional Chondrocyte-Macrophage Coculture System to Probe Inflammation in Experimental Osteoarthritis. Tissue Eng Part A 23, 101-114.
Shannon, S., Jia, D., Entersz, I., Beelen, P., Yu, M., Carcione, C., Carcione, J., Mahtabfar, A., Vaca, C., Weaver, M., et al. (2017). Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901. BMC Cancer 17, 121.
Short, A. R., Czeisler, C., Stocker, B., Cole, S., Otero, J. J., and Winter, J. O. (2017). Imaging Cell-Matrix Interactions in 3D Collagen Hydrogel Culture Systems. Macromol Biosci.
Sittadjody, S., Saul, J. M., and Opara, E. C. (2017). Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules. Methods Mol Biol 1479, 225-235.
Strobel, H. A., Dikina, A. D., Levi, K., Solorio, L. D., Alsberg, E., and Rolle, M. W. (2017). Cellular Self-Assembly with Microsphere Incorporation for Growth Factor Delivery Within Engineered Vascular Tissue Rings. Tissue Eng Part A 23, 143-155.
Terrasso, A. P., Silva, A. C., Filipe, A., Pedroso, P., Ferreira, A. L., Alves, P. M., and Brito, C. (2017). Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds. J Pharmacol Toxicol Methods 83, 72-79.
Thon, J. N., Dykstra, B. J., and Beaulieu, L. M. (2017). Platelet bioreactor: accelerated evolution of design and manufacture. Platelets, 1-6.
Tian, X., Brookes, O., and Battaglia, G. (2017). Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier. Sci Rep 7, 39676.
Tokuda, E. Y., Jones, C. E., and Anseth, K. S. (2017). PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity. Integr Biol (Camb) 9, 76-87.
Ukaji, T., Lin, Y., Okada, S., and Umezawa, K. (2017). Inhibition of MMP-2-mediated cellular invasion by NF-kappaB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis. Biochem Biophys Res Commun.
van den Brand, D., Massuger, L. F., Brock, R., and Verdurmen, W. P. (2017). Mimicking Tumors: Towards More Predictive In Vitro Models for Peptide- and Protein-Conjugated Drugs. Bioconjug Chem.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C., and Cress, A. E. (2017). A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci 130, 104-110.
Yang, G., Long, H., Ren, X., Ma, K., Xiao, Z., Wang, Y., and Guo, Y. (2017). Regulation of adipose-tissue-derived stromal cell orientation and motility in 2D- and 3D-cultures by direct-current electrical field. Dev Growth Differ.
Yildiz-Ozturk, E., Gulce-Iz, S., Anil, M., and Yesil-Celiktas, O. (2017). Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture. Cytotechnology.
Zhao, Y., Qiao, S., Shi, S., Yao, L., Hou, X., Li, C., Lin, F. H., Guo, K., Acharya, A., Chen, X., et al. (2017). Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS Appl Mater Interfaces.
Zheng, Z., Ran, J., Chen, W., Hu, Y., Zhu, T., Chen, X., Yin, Z., Heng, B. C., Feng, G., Le, H., et al. (2017). Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair. Acta Biomater.
Zhou, Z., Yi, Q., Xia, T., Yin, W., Kadi, A. A., Li, J., and Zhang, Y. (2017). A photo-degradable supramolecular hydrogel for selective delivery of microRNA into 3D-cultured cells. Org Biomol Chem.
Zhu, Z., and Yang, C. J. (2017). Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis. Acc Chem Res 50, 22-31.
Microfluidics
Banaeiyan, A. A., Theobald, J., Paukstyte, J., Wolfl, S., Adiels, C. B., and Goksor, M. (2017). Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication 9, 015014.
Du, Y., Li, N., Yang, H., Luo, C., Gong, Y., Tong, C., Gao, Y., Lu, S., and Long, M. (2017). Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip. Lab Chip.
Houshmand, M., Soleimani, M., Atashi, A., Saglio, G., Abdollahi, M., and Nikougoftar Zarif, M. (2017). Mimicking the Acute Myeloid Leukemia Niche for Molecular Study and Drug Screening. Tissue Eng Part C Methods.
Ibrahim, M., and Richardson, M. K. (2017). In vitro development of zebrafish vascular networks. Reprod Toxicol.
Jeon, S. J., and Hayward, R. C. (2017). Reconfigurable Microscale Frameworks from Concatenated Helices with Controlled Chirality. Adv Mater.
Kaisar, M. A., Sajja, R. K., Prasad, S., Abhyankar, V. V., Liles, T., and Cucullo, L. (2017). New experimental models of the blood-brain barrier for CNS drug discovery. Expert Opin Drug Discov 12, 89-103.
Leclerc, E., Kimura, K., Shinohara, M., Danoy, M., Le Gall, M., Kido, T., Miyajima, A., Fujii, T., and Sakai, Y. (2017). Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment. Genomics 109, 16-26.
Li, R., Hebert, J. D., Lee, T. A., Xing, H., Boussommier-Calleja, A., Hynes, R. O., Lauffenburger, D. A., and Kamm, R. D. (2017a). Macrophage-Secreted TNFalpha and TGFbeta1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. Cancer Res 77, 279-290.
Li, X., Brooks, J. C., Hu, J., Ford, K. I., and Easley, C. J. (2017b). 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17, 341-349.
Lienemann, P. S., Rossow, T., Mao, A. S., Vallmajo-Martin, Q., Ehrbar, M., and Mooney, D. J. (2017). Single cell-laden protease-sensitive microniches for long-term culture in 3D. Lab Chip 17, 727-737.
Nguyen, D. T., van Noort, D., Jeong, I. K., and Park, S. (2017). Endocrine system on chip for a diabetes treatment model. Biofabrication 9, 015021.
Piotrowski-Daspit, A. S., Simi, A. K., Pang, M. F., Tien, J., and Nelson, C. M. (2017). A 3D Culture Model to Study How Fluid Pressure and Flow Affect the Behavior of Aggregates of Epithelial Cells. Methods Mol Biol 1501, 245-257.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Thon, J. N., Dykstra, B. J., and Beaulieu, L. M. (2017). Platelet bioreactor: accelerated evolution of design and manufacture. Platelets, 1-6.
Yildiz-Ozturk, E., Gulce-Iz, S., Anil, M., and Yesil-Celiktas, O. (2017). Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture. Cytotechnology.
Zhang, W., Lee, W. Y., and Zilberberg, J. (2017). Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma. Methods Mol Biol 1513, 171-191.
Zhu, Z., and Yang, C. J. (2017). Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis. Acc Chem Res 50, 22-31.
Zuchowska, A., Kwapiszewska, K., Chudy, M., Dybko, A., and Brzozka, Z. (2017). Studies of anticancer drug cytotoxicity based on long-term HepG2 spheroid culture in a microfluidic system. Electrophoresis.
Microfabrication
Banaeiyan, A. A., Theobald, J., Paukstyte, J., Wolfl, S., Adiels, C. B., and Goksor, M. (2017). Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication 9, 015014.
Jeon, S. J., and Hayward, R. C. (2017). Reconfigurable Microscale Frameworks from Concatenated Helices with Controlled Chirality. Adv Mater.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Bone
Bendtsen, S. T., Quinnell, S. P., and Wei, M. (2017). Development of a novel alginate-polyvinyl alcohol-hydroxyapatite hydrogel for 3D bioprinting bone tissue engineered scaffolds. J Biomed Mater Res A.
Binner, M., Bray, L. J., Friedrichs, J., Freudenberg, U., Tsurkan, M. V., and Werner, C. (2017). Cell-instructive starPEG-heparin-collagen composite matrices. Acta Biomater.
Chatzinikolaidou, M., Pontikoglou, C., Terzaki, K., Kaliva, M., Kalyva, A., Papadaki, E., Vamvakaki, M., and Farsari, M. (2017). Recombinant human bone morphogenetic protein 2 (rhBMP-2) immobilized on laser-fabricated 3D scaffolds enhance osteogenesis. Colloids Surf B Biointerfaces 149, 233-242.
Chen, G., Xu, R., Zhang, C., and Lv, Y. (2017). Responses of MSCs to 3D Scaffold Matrix Mechanical Properties under Oscillatory Perfusion Culture. ACS Appl Mater Interfaces 9, 1207-1218.
Correia, C. R., Santos, T. C., Pirraco, R. P., Cerqueira, M. T., Marques, A. P., Reis, R. L., and Mano, J. F. (2017). In vivo osteogenic differentiation of stem cells inside compartmentalized capsules loaded with co-cultured endothelial cells. Acta Biomater.
Ding, H., Zhong, J., Xu, F., Song, F., Yin, M., Wu, Y., Hu, Q., and Wang, J. (2017). Establishment of 3D culture and induction of osteogenic differentiation of pre-osteoblasts using wet-collected aligned scaffolds. Mater Sci Eng C Mater Biol Appl 71, 222-230.
Emmakah, A. M., Arman, H., Bragg, J., Greene, T., Alvarez, M., Childress, P., Goebel, W. S., Kacena, M., Lin, C. C., and Chu, T. M. (2017). A Fast-Degrading Thiol-Acrylate based Hydrogel for Cranial Regeneration. Biomed Mater.
Fang, Y., Wang, B., Zhao, Y., Xiao, Z., Li, J., Cui, Y., Han, S., Wei, J., Chen, B., Han, J., et al. (2017). Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells. Sci Rep 7, 42049.
Gao, G., Zhang, X. F., Hubbell, K., and Cui, X. (2017). NR2F2 regulates chondrogenesis of human mesenchymal stem cells in bioprinted cartilage. Biotechnol Bioeng 114, 208-216.
Houshmand, M., Soleimani, M., Atashi, A., Saglio, G., Abdollahi, M., and Nikougoftar Zarif, M. (2017). Mimicking the Acute Myeloid Leukemia Niche for Molecular Study and Drug Screening. Tissue Eng Part C Methods.
Kaynak Bayrak, G., Demirtas, T. T., and Gumusderelioglu, M. (2017). Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds. Carbohydr Polym 157, 803-813.
Middendorf, J. M., Griffin, D. J., Shortkroff, S., Dugopolski, C., Kennedy, S., Siemiatkoski, J., Cohen, I., and Bonassar, L. J. (2017). Mechanical properties and structure-function relationships of human chondrocyte-seeded cartilage constructs after in vitro culture. J Orthop Res.
Moghadam, M. Z., Hassanajili, S., Esmaeilzadeh, F., Ayatollahi, M., and Ahmadi, M. (2017). Formation of porous HPCL/LPCL/HA scaffolds with supercritical CO2 gas foaming method. J Mech Behav Biomed Mater 69, 115-127.
Nih, L. R., Moshayedi, P., Llorente, I. L., Berg, A. R., Cinkornpumin, J., Lowry, W. E., Segura, T., and Carmichael, S. T. (2017). Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief 10, 202-209.
Paino, F., La Noce, M., Giuliani, A., De Rosa, A., Mazzoni, S., Laino, L., Amler, E., Papaccio, G., Desiderio, V., and Tirino, V. (2017). hDPSCs fabricate a vascularised woven bone tissue: a new tool in bone tissue engineering. Clin Sci (Lond).
Parreno, J., Nabavi Niaki, M., Andrejevic, K., Jiang, A., Wu, P. H., and Kandel, R. A. (2017). Interplay between cytoskeletal polymerization and the chondrogenic phenotype in chondrocytes passaged in monolayer culture. J Anat 230, 234-248.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Regmi, S., Cao, J., Pathak, S., Gupta, B., Kumar Poudel, B., Tung, P. T., Yook, S., Park, J. B., Yong, C. S., Kim, J. O., et al. (2017). A three-dimensional assemblage of gingiva-derived mesenchymal stem cells and NO-releasing microspheres for improved differentiation. Int J Pharm 520, 163-172.
Shumilova, A. A., Myltygashev, M. P., Kirichenko, A. K., Nikolaeva, E. D., Volova, T. G., and Shishatskaya, E. I. (2017). Porous 3D implants of degradable poly-3-hydroxybutyrate used to enhance regeneration of rat cranial defect. J Biomed Mater Res A 105, 566-577.
Thon, J. N., Dykstra, B. J., and Beaulieu, L. M. (2017). Platelet bioreactor: accelerated evolution of design and manufacture. Platelets, 1-6.
Uz, M., Buyukoz, M., Sharma, A. D., Sakaguchi, D. S., Altinkaya, S. A., and Mallapragada, S. K. (2017). Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes. Acta Biomater.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Bone Marrow
Binner, M., Bray, L. J., Friedrichs, J., Freudenberg, U., Tsurkan, M. V., and Werner, C. (2017). Cell-instructive starPEG-heparin-collagen composite matrices. Acta Biomater.
Chatzinikolaidou, M., Pontikoglou, C., Terzaki, K., Kaliva, M., Kalyva, A., Papadaki, E., Vamvakaki, M., and Farsari, M. (2017). Recombinant human bone morphogenetic protein 2 (rhBMP-2) immobilized on laser-fabricated 3D scaffolds enhance osteogenesis. Colloids Surf B Biointerfaces 149, 233-242.
Fang, Y., Wang, B., Zhao, Y., Xiao, Z., Li, J., Cui, Y., Han, S., Wei, J., Chen, B., Han, J., et al. (2017). Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells. Sci Rep 7, 42049.
Gao, G., Zhang, X. F., Hubbell, K., and Cui, X. (2017). NR2F2 regulates chondrogenesis of human mesenchymal stem cells in bioprinted cartilage. Biotechnol Bioeng 114, 208-216.
Houshmand, M., Soleimani, M., Atashi, A., Saglio, G., Abdollahi, M., and Nikougoftar Zarif, M. (2017). Mimicking the Acute Myeloid Leukemia Niche for Molecular Study and Drug Screening. Tissue Eng Part C Methods.
Shumilova, A. A., Myltygashev, M. P., Kirichenko, A. K., Nikolaeva, E. D., Volova, T. G., and Shishatskaya, E. I. (2017). Porous 3D implants of degradable poly-3-hydroxybutyrate used to enhance regeneration of rat cranial defect. J Biomed Mater Res A 105, 566-577.
Thon, J. N., Dykstra, B. J., and Beaulieu, L. M. (2017). Platelet bioreactor: accelerated evolution of design and manufacture. Platelets, 1-6.
Uz, M., Buyukoz, M., Sharma, A. D., Sakaguchi, D. S., Altinkaya, S. A., and Mallapragada, S. K. (2017). Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes. Acta Biomater.
Breast
Barr, S., Hill, E. W., and Bayat, A. (2017). Development, fabrication and evaluation of a novel biomimetic human breast tissue derived breast implant surface. Acta Biomater 49, 260-271.
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Cepeda, M. A., Evered, C. L., Pelling, J. J., and Damjanovski, S. (2017a). Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels. J Cell Commun Signal.
Cepeda, M. A., Pelling, J. J., Evered, C. L., Leong, H. S., and Damjanovski, S. (2017b). The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells. Exp Cell Res 350, 169-183.
Fuzer, A. M., Lee, S. Y., Mott, J. D., and Cominetti, M. R. (2017). [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. J Cell Biochem.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Li, L., Chen, J., Xiong, G., St Clair, D. K., Xu, W., and Xu, R. (2017). Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. J Cell Sci 130, 190-202.
Perin, N., Bobanovic, K., Zlatar, I., Jelic, D., Kelava, V., Kostrun, S., Markovic, V. G., Brajsa, K., and Hranjec, M. (2017). Antiproliferative activity of amino substituted benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles explored by 2D and 3D cell culture system. Eur J Med Chem 125, 722-735.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Pradhan, S., Hassani, I., Seeto, W. J., and Lipke, E. A. (2017). PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture. J Biomed Mater Res A 105, 236-252.
Qu, Y., Han, B., Gao, B., Bose, S., Gong, Y., Wawrowsky, K., Giuliano, A. E., Sareen, D., and Cui, X. (2017). Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports 8, 205-215.
Tang, X., Wang, X., Zhao, Y. Y., Curtis, J. M., and Brindley, D. N. (2017). Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-kappaB activation. Mol Cancer 16, 36.
Ukaji, T., Lin, Y., Okada, S., and Umezawa, K. (2017). Inhibition of MMP-2-mediated cellular invasion by NF-kappaB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis. Biochem Biophys Res Commun.
Yildiz-Ozturk, E., Gulce-Iz, S., Anil, M., and Yesil-Celiktas, O. (2017). Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture. Cytotechnology.
Zhao, Y., Qiao, S., Shi, S., Yao, L., Hou, X., Li, C., Lin, F. H., Guo, K., Acharya, A., Chen, X., et al. (2017). Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS Appl Mater Interfaces.
Colon
Cheong, J. G., Song, D. G., Song, H. E., Berditchevski, F., Nam, S. H., Jung, J. W., Kim, H. J., Kim, J. E., Kim, S., Ryu, J., et al. (2017). Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment. Oncotarget.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Riedl, A., Schlederer, M., Pudelko, K., Stadler, M., Walter, S., Unterleuthner, D., Unger, C., Kramer, N., Hengstschlager, M., Kenner, L., et al. (2017). Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses. J Cell Sci 130, 203-218.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Heart
Borovjagin, A. V., Ogle, B. M., Berry, J. L., and Zhang, J. (2017). From Microscale Devices to 3D Printing: Advances in Fabrication of 3D Cardiovascular Tissues. Circ Res 120, 150-165.
He, X., and Toth, T. L. (2017). In vitro culture of ovarian follicles from Peromyscus. Semin Cell Dev Biol 61, 140-149.
Hogrebe, N. J., Reinhardt, J. W., and Gooch, K. J. (2017). Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization. J Biomed Mater Res A 105, 640-661.
Li, X., Brooks, J. C., Hu, J., Ford, K. I., and Easley, C. J. (2017). 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17, 341-349.
Liau, B., Jackman, C. P., Li, Y., and Bursac, N. (2017). Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. Sci Rep 7, 42290.
Pagano, F., Angelini, F., Siciliano, C., Tasciotti, J., Mangino, G., De Falco, E., Carnevale, R., Sciarretta, S., Frati, G., and Chimenti, I. (2017). Beta2-adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation. Pharmacol Res.
Liver
Angioni, M. M., Bellofatto, K., Merlin, S., Menegon, S., Perra, A., Petrelli, A., Sulas, P., Giordano, S., Columbano, A., and Follenzi, A. (2017). A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis. Oncotarget.
Banaeiyan, A. A., Theobald, J., Paukstyte, J., Wolfl, S., Adiels, C. B., and Goksor, M. (2017). Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication 9, 015014.
Chitrangi, S., Nair, P., and Khanna, A. (2017). 3D engineered In vitro hepatospheroids for studying drug toxicity and metabolism. Toxicol In Vitro 38, 8-18.
Du, Y., Li, N., Yang, H., Luo, C., Gong, Y., Tong, C., Gao, Y., Lu, S., and Long, M. (2017). Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip. Lab Chip.
Funk, C., and Roth, A. (2017). Current limitations and future opportunities for prediction of DILI from in vitro. Arch Toxicol 91, 131-142.
Gao, Q., Wang, Z. C., Duan, M., Lin, Y. H., Zhou, X. Y., Worthley, D. L., Wang, X. Y., Niu, G., Xia, Y., Deng, M., et al. (2017). Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. Gastroenterology 152, 232-242.e234.
Jeon, H., Kang, K., Park, S. A., Kim, W. D., Paik, S. S., Lee, S. H., Jeong, J., and Choi, D. (2017). Generation of Multilayered 3D Structures of HepG2 Cells Using a Bio-printing Technique. Gut Liver 11, 121-128.
Kostrzewski, T., Cornforth, T., Snow, S. A., Ouro-Gnao, L., Rowe, C., Large, E. M., and Hughes, D. J. (2017). Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease. World J Gastroenterol 23, 204-215.
Leclerc, E., Kimura, K., Shinohara, M., Danoy, M., Le Gall, M., Kido, T., Miyajima, A., Fujii, T., and Sakai, Y. (2017). Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment. Genomics 109, 16-26.
Li, X., Brooks, J. C., Hu, J., Ford, K. I., and Easley, C. J. (2017a). 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17, 341-349.
Li, Y., Wu, Q., Wang, Y., Li, L., Chen, F., Shi, Y., Bao, J., and Bu, H. (2017b). Construction of bioengineered hepatic tissue derived from human umbilical cord mesenchymal stem cells via aggregation culture in porcine decellularized liver scaffolds. Xenotransplantation.
Li, Y., Wu, Q., Wang, Y., Li, L., Chen, F., Shi, Y., Bu, H., and Bao, J. (2017c). Immunogenicity of hepatic differentiated human umbilical cord mesenchymal stem cells promoted by porcine decellularized liver scaffolds. Xenotransplantation.
Luckert, C., Schulz, C., Lehmann, N., Thomas, M., Hofmann, U., Hammad, S., Hengstler, J. G., Braeuning, A., Lampen, A., and Hessel, S. (2017). Comparative analysis of 3D culture methods on human HepG2 cells. Arch Toxicol 91, 393-406.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Tanimizu, N., and Mitaka, T. (2017). Epithelial Morphogenesis during Liver Development. Cold Spring Harb Perspect Biol.
Weltin, A., Hammer, S., Noor, F., Kaminski, Y., Kieninger, J., and Urban, G. A. (2017). Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Biosens Bioelectron 87, 941-948.
Zuchowska, A., Kwapiszewska, K., Chudy, M., Dybko, A., and Brzozka, Z. (2017). Studies of anticancer drug cytotoxicity based on long-term HepG2 spheroid culture in a microfluidic system. Electrophoresis.
Lung
Amoedo, N. D., Obre, E., and Rossignol, R. (2017). Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy. Biochim Biophys Acta.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Foster, M. W., Gwinn, W. M., Kelly, F. L., Brass, D. M., Valente, A. M., Moseley, M. A., Thompson, J. W., Morgan, D. L., and Palmer, S. M. (2017). Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl. J Proteome Res 16, 538-549.
He, X., and Toth, T. L. (2017). In vitro culture of ovarian follicles from Peromyscus. Semin Cell Dev Biol 61, 140-149.
Hogrebe, N. J., Reinhardt, J. W., and Gooch, K. J. (2017). Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization. J Biomed Mater Res A 105, 640-661.
Ji, J., Hedelin, A., Malmlof, M., Kessler, V., Seisenbaeva, G., Gerde, P., and Palmberg, L. (2017). Development of Combining of Human Bronchial Mucosa Models with XposeALI(R) for Exposure of Air Pollution Nanoparticles. PLoS One 12, e0170428.
Link, P. A., Pouliot, R. A., Mikhaiel, N. S., Young, B. M., and Heise, R. L. (2017). Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture. J Vis Exp.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Tan, Q., Choi, K. M., Sicard, D., and Tschumperlin, D. J. (2017). Human airway organoid engineering as a step toward lung regeneration and disease modeling. Biomaterials 113, 118-132.
Muscle
Abe, T., Ohuchida, K., Koikawa, K., Endo, S., Okumura, T., Sada, M., Horioka, K., Zheng, B., Moriyama, T., Nakata, K., et al. (2017). Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination. Int J Oncol 50, 457-467.
Ganesan, M. K., Finsterwalder, R., Leb, H., Resch, U., Neumuller, K., de Martin, R., and Petzelbauer, P. (2017). Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells. Tissue Eng Part C Methods 23, 38-49.
Kasper, A. M., Turner, D. C., Martin, N. R., and Sharples, A. P. (2017). Mimicking Exercise in Three-Dimensional Bioengineered Skeletal Muscle to Investigate Cellular and Molecular Mechanisms of Physiological Adaptation. J Cell Physiol.
Li, M., Nagamori, E., and Kino-Oka, M. (2017a). Disruption of myoblast alignment by highly motile rhabdomyosarcoma cell in tissue structure. J Biosci Bioeng 123, 259-264.
Li, X., Brooks, J. C., Hu, J., Ford, K. I., and Easley, C. J. (2017b). 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17, 341-349.
Nakamura, T., Takagi, S., Kamon, T., Yamasaki, K. I., and Fujisato, T. (2017). Development and evaluation of a removable tissue-engineered muscle with artificial tendons. J Biosci Bioeng 123, 265-271.
Strobel, H. A., Dikina, A. D., Levi, K., Solorio, L. D., Alsberg, E., and Rolle, M. W. (2017). Cellular Self-Assembly with Microsphere Incorporation for Growth Factor Delivery Within Engineered Vascular Tissue Rings. Tissue Eng Part A 23, 143-155.
Nerve
Adak, A., Das, G., Barman, S., Mohapatra, S., Bhunia, D., Jana, B., and Ghosh, S. (2017). Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug. ACS Appl Mater Interfaces 9, 5067-5076.
Adil, M. M., Rodrigues, G. M., Kulkarni, R. U., Rao, A. T., Chernavsky, N. E., Miller, E. W., and Schaffer, D. V. (2017). Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform. Sci Rep 7, 40573.
Drobnik, J., Pietrucha, K., Kudzin, M., Mader, K., Szymanski, J., and Szczepanowska, A. (2017). Comparison of various types of collagenous scaffolds applied for embryonic nerve cell culture. Biologicals.
Uz, M., Buyukoz, M., Sharma, A. D., Sakaguchi, D. S., Altinkaya, S. A., and Mallapragada, S. K. (2017). Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes. Acta Biomater.
Vagaska, B., and Ferretti, P. (2017). Toward modeling the human nervous system in a dish: recent progress and outstanding challenges. Regen Med 12, 15-23.
Wang, S., Ghezzi, C. E., Gomes, R., Pollard, R. E., Funderburgh, J. L., and Kaplan, D. L. (2017). In vitro 3D corneal tissue model with epithelium, stroma, and innervation. Biomaterials 112, 1-9.
Prostate
Backer, A., Erhardt, O., Wietbrock, L., Schel, N., Goppert, B., Dirschka, M., Abaffy, P., Sollich, T., Cecilia, A., and Gruhl, F. J. (2017). Silk scaffolds connected with different naturally occurring biomaterials for prostate cancer cell cultivation in 3D. Biopolymers 107, 70-79.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Cepeda, M. A., Pelling, J. J., Evered, C. L., Leong, H. S., and Damjanovski, S. (2017). The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells. Exp Cell Res 350, 169-183.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Martinez de Pinillos Bayona, A., Woodhams, J. H., Pye, H., Hamoudi, R. A., Moore, C. M., and MacRobert, A. J. (2017). Efficacy of photochemical internalisation using disulfonated chlorin and porphyrin photosensitisers: an in vitro study in 2D and 3D prostate cancer models. Cancer Lett.
Sittadjody, S., Saul, J. M., and Opara, E. C. (2017). Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules. Methods Mol Biol 1479, 225-235.
Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C., and Cress, A. E. (2017). A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci 130, 104-110.
Endothelial cells
Angiolini, V. A., Cruz, C. U., Lopez, M. L., Simon, L., and Matte, U. (2017). Alginate-embedded HuH-7 cells increase MMP-9 and reduce OCLN expression in vitro. Cancer Cell Int 17, 5.
Binner, M., Bray, L. J., Friedrichs, J., Freudenberg, U., Tsurkan, M. V., and Werner, C. (2017). Cell-instructive starPEG-heparin-collagen composite matrices. Acta Biomater.
Correia, C. R., Santos, T. C., Pirraco, R. P., Cerqueira, M. T., Marques, A. P., Reis, R. L., and Mano, J. F. (2017). In vivo osteogenic differentiation of stem cells inside compartmentalized capsules loaded with co-cultured endothelial cells. Acta Biomater.
Du, Y., Li, N., Yang, H., Luo, C., Gong, Y., Tong, C., Gao, Y., Lu, S., and Long, M. (2017). Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip. Lab Chip.
Foster, J. W., Wahlin, K., Adams, S. M., Birk, D. E., Zack, D. J., and Chakravarti, S. (2017). Cornea organoids from human induced pluripotent stem cells. Sci Rep 7, 41286.
Ganesan, M. K., Finsterwalder, R., Leb, H., Resch, U., Neumuller, K., de Martin, R., and Petzelbauer, P. (2017). Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells. Tissue Eng Part C Methods 23, 38-49.
Hernandez-Fernaud, J. R., Ruengeler, E., Casazza, A., Neilson, L. J., Pulleine, E., Santi, A., Ismail, S., Lilla, S., Dhayade, S., MacPherson, I. R., et al. (2017). Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nat Commun 8, 14206.
Ibrahim, M., and Richardson, M. K. (2017). In vitro development of zebrafish vascular networks. Reprod Toxicol.
Leclerc, E., Kimura, K., Shinohara, M., Danoy, M., Le Gall, M., Kido, T., Miyajima, A., Fujii, T., and Sakai, Y. (2017). Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment. Genomics 109, 16-26.
Partyka, P. P., Godsey, G. A., Galie, J. R., Kosciuk, M. C., Acharya, N. K., Nagele, R. G., and Galie, P. A. (2017). Mechanical stress regulates transport in a compliant 3D model of the blood-brain barrier. Biomaterials 115, 30-39.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Russell, M. R., Lerner, T. R., Burden, J. J., Nkwe, D. O., Pelchen-Matthews, A., Domart, M. C., Durgan, J., Weston, A., Jones, M. L., Peddie, C. J., et al. (2017). 3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy. J Cell Sci 130, 278-291.
Tan, Q., Choi, K. M., Sicard, D., and Tschumperlin, D. J. (2017). Human airway organoid engineering as a step toward lung regeneration and disease modeling. Biomaterials 113, 118-132.
Tang, X., Wang, X., Zhao, Y. Y., Curtis, J. M., and Brindley, D. N. (2017). Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-kappaB activation. Mol Cancer 16, 36.
Tian, X., Brookes, O., and Battaglia, G. (2017). Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier. Sci Rep 7, 39676.
Xue, C., Xie, J., Zhao, D., Lin, S., Zhou, T., Shi, S., Shao, X., Lin, Y., Zhu, B., and Cai, X. (2017). The JAK/STAT3 signalling pathway regulated angiogenesis in an endothelial cell/adipose-derived stromal cell co-culture, 3D gel model. Cell Prolif 50.
Zhang, F., Wang, L., Li, Y., Liu, W., Duan, F., Huang, R., Chen, X., Chang, S. C., Du, Y., and Na, J. (2017). Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells. Stem Cell Res Ther 8, 6.
Fibroblast
Barr, S., Hill, E. W., and Bayat, A. (2017). Development, fabrication and evaluation of a novel biomimetic human breast tissue derived breast implant surface. Acta Biomater 49, 260-271.
Franco-Barraza, J., Francescone, R., Luong, T., Shah, N., Madhani, R., Cukierman, G., Dulaimi, E., Devarajan, K., Egleston, B. L., Nicolas, E., et al. (2017). Matrix-regulated integrin alphavbeta5 maintains alpha5beta1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife 6.
Gao, Q., Wang, Z. C., Duan, M., Lin, Y. H., Zhou, X. Y., Worthley, D. L., Wang, X. Y., Niu, G., Xia, Y., Deng, M., et al. (2017). Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. Gastroenterology 152, 232-242.e234.
Holmes, D. B., and Heine, V. M. (2017). Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open.
Ji, J., Hedelin, A., Malmlof, M., Kessler, V., Seisenbaeva, G., Gerde, P., and Palmberg, L. (2017). Development of Combining of Human Bronchial Mucosa Models with XposeALI(R) for Exposure of Air Pollution Nanoparticles. PLoS One 12, e0170428.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Parreno, J., Nabavi Niaki, M., Andrejevic, K., Jiang, A., Wu, P. H., and Kandel, R. A. (2017). Interplay between cytoskeletal polymerization and the chondrogenic phenotype in chondrocytes passaged in monolayer culture. J Anat 230, 234-248.
Stem Cells
Banaeiyan, A. A., Theobald, J., Paukstyte, J., Wolfl, S., Adiels, C. B., and Goksor, M. (2017). Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication 9, 015014.
Chacon-Martinez, C. A., Klose, M., Niemann, C., Glauche, I., and Wickstrom, S. A. (2017). Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny. Embo j 36, 151-164.
Chitrangi, S., Nair, P., and Khanna, A. (2017). 3D engineered In vitro hepatospheroids for studying drug toxicity and metabolism. Toxicol In Vitro 38, 8-18.
Edgar, J. M., Robinson, M., and Willerth, S. M. (2017). Fibrin hydrogels induce mixed dorsal/ventral spinal neuron identities during differentiation of human induced pluripotent stem cells. Acta Biomater.
Funk, C., and Roth, A. (2017). Current limitations and future opportunities for prediction of DILI from in vitro. Arch Toxicol 91, 131-142.
Galuppo, A. G., Chagastelles, P. C., Gamba, D., Iglesias, D. B., Sperling, L. E., Machado, J., Petry, J. F., Wendorff, J., Petzhold, C. L., and Pranke, P. (2017). Effect of feeder free poly(lactide-co-glycolide) scaffolds on morphology, proliferation, and pluripotency of mouse embryonic stem cells. J Biomed Mater Res A 105, 424-432.
Gwon, K., Kim, E., and Tae, G. (2017). Heparin-hyaluronic acid hydrogel in support of cellular activities of 3D encapsulated adipose derived stem cells. Acta Biomater 49, 284-295.
Holmes, D. B., and Heine, V. M. (2017). Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open.
Homma, K., Usui, S., and Kaneda, M. (2017). Knock-in strategy at 3'-end of Crx gene by CRISPR/Cas9 system shows the gene expression profiles during human photoreceptor differentiation. Genes Cells.
Houshmand, M., Soleimani, M., Atashi, A., Saglio, G., Abdollahi, M., and Nikougoftar Zarif, M. (2017). Mimicking the Acute Myeloid Leukemia Niche for Molecular Study and Drug Screening. Tissue Eng Part C Methods.
Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J., and Chidgey, A. P. (2017). Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation. Biomaterials 118, 1-15.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Kaisar, M. A., Sajja, R. K., Prasad, S., Abhyankar, V. V., Liles, T., and Cucullo, L. (2017). New experimental models of the blood-brain barrier for CNS drug discovery. Expert Opin Drug Discov 12, 89-103.
Koivisto, J. T., Joki, T., Parraga, J., Paakkonen, R., Yla-Outinen, L., Salonen, L., Jonkkari, I., Peltola, M., Ihalainen, T., Narkilahti, S., and Kellomaki, M. (2017). Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering. Biomed Mater.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Li, Y., He, L., Pan, S., Zhang, L., Zhang, W., Yi, H., and Niu, Y. (2017a). Three-dimensional simulated microgravity culture improves the proliferation and odontogenic differentiation of dental pulp stem cell in PLGA scaffolds implanted in mice. Mol Med Rep 15, 873-878.
Li, Y., Wu, Q., Wang, Y., Li, L., Chen, F., Shi, Y., Bao, J., and Bu, H. (2017b). Construction of bioengineered hepatic tissue derived from human umbilical cord mesenchymal stem cells via aggregation culture in porcine decellularized liver scaffolds. Xenotransplantation.
Liau, B., Jackman, C. P., Li, Y., and Bursac, N. (2017). Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. Sci Rep 7, 42290.
Lienemann, P. S., Rossow, T., Mao, A. S., Vallmajo-Martin, Q., Ehrbar, M., and Mooney, D. J. (2017). Single cell-laden protease-sensitive microniches for long-term culture in 3D. Lab Chip 17, 727-737.
Nakaoka, T., Saito, Y., Shimamoto, Y., Muramatsu, T., Kimura, M., Kanai, Y., and Saito, H. (2017). The cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids. Cancer Sci.
Nie, J., and Hashino, E. (2017). Organoid technologies meet genome engineering. EMBO Rep.
Nih, L. R., Moshayedi, P., Llorente, I. L., Berg, A. R., Cinkornpumin, J., Lowry, W. E., Segura, T., and Carmichael, S. T. (2017). Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief 10, 202-209.
Ouyang, A., Cerchiari, A. E., Tang, X., Liebenberg, E., Alliston, T., Gartner, Z. J., and Lotz, J. C. (2017). Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells. J Orthop Res 35, 61-73.
Pamies, D., and Hartung, T. (2017). 21st Century Cell Culture for 21st Century Toxicology. Chem Res Toxicol 30, 43-52.
Pompaiah, M., and Bartfeld, S. (2017). Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis. Curr Top Microbiol Immunol 400, 149-168.
Qu, Y., Han, B., Gao, B., Bose, S., Gong, Y., Wawrowsky, K., Giuliano, A. E., Sareen, D., and Cui, X. (2017). Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports 8, 205-215.
Regmi, S., Cao, J., Pathak, S., Gupta, B., Kumar Poudel, B., Tung, P. T., Yook, S., Park, J. B., Yong, C. S., Kim, J. O., et al. (2017). A three-dimensional assemblage of gingiva-derived mesenchymal stem cells and NO-releasing microspheres for improved differentiation. Int J Pharm 520, 163-172.
Sandstrom, J., Eggermann, E., Charvet, I., Roux, A., Toni, N., Greggio, C., Broyer, A., Monnet-Tschudi, F., and Stoppini, L. (2017). Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing. Toxicol In Vitro 38, 124-135.
Sisakhtnezhad, S., Alimoradi, E., and Akrami, H. (2017). External factors influencing mesenchymal stem cell fate in vitro. Eur J Cell Biol 96, 13-33.
Vagaska, B., and Ferretti, P. (2017). Toward modeling the human nervous system in a dish: recent progress and outstanding challenges. Regen Med 12, 15-23.
Yang, J. P., Anderson, A. E., McCartney, A., Ory, X., Ma, G., Pappalardo, E., Bader, J., and Elisseeff, J. (2017). Metabolically active 3-dimensional brown adipose tissue engineered from white adipose-derived stem cells. Tissue Eng Part A.
Zhang, F., Wang, L., Li, Y., Liu, W., Duan, F., Huang, R., Chen, X., Chang, S. C., Du, Y., and Na, J. (2017). Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells. Stem Cell Res Ther 8, 6.
Zheng, Z., Ran, J., Chen, W., Hu, Y., Zhu, T., Chen, X., Yin, Z., Heng, B. C., Feng, G., Le, H., et al. (2017). Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair. Acta Biomater.
Stromal Cells
Abe, T., Ohuchida, K., Koikawa, K., Endo, S., Okumura, T., Sada, M., Horioka, K., Zheng, B., Moriyama, T., Nakata, K., et al. (2017). Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination. Int J Oncol 50, 457-467.
Bianchi, V. J., Weber, J. F., Waldman, S. D., Backstein, D., and Kandel, R. A. (2017). Formation of Hyaline Cartilage Tissue by Passaged Human Osteoarthritic Chondrocytes. Tissue Eng Part A 23, 156-165.
Brancato, V., Comunanza, V., Imparato, G., Cora, D., Urciuolo, F., Noghero, A., Bussolino, F., and Netti, P. A. (2017). Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer. Acta Biomater 49, 152-166.
Foster, J. W., Wahlin, K., Adams, S. M., Birk, D. E., Zack, D. J., and Chakravarti, S. (2017). Cornea organoids from human induced pluripotent stem cells. Sci Rep 7, 41286.
Franco-Barraza, J., Francescone, R., Luong, T., Shah, N., Madhani, R., Cukierman, G., Dulaimi, E., Devarajan, K., Egleston, B. L., Nicolas, E., et al. (2017). Matrix-regulated integrin alphavbeta5 maintains alpha5beta1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife 6.
Ghezzi, C. E., Marelli, B., Omenetto, F. G., Funderburgh, J. L., and Kaplan, D. L. (2017). 3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture. PLoS One 12, e0169504.
Hernandez-Fernaud, J. R., Ruengeler, E., Casazza, A., Neilson, L. J., Pulleine, E., Santi, A., Ismail, S., Lilla, S., Dhayade, S., MacPherson, I. R., et al. (2017). Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nat Commun 8, 14206.
Hogrebe, N. J., Reinhardt, J. W., and Gooch, K. J. (2017). Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization. J Biomed Mater Res A 105, 640-661.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Novikov, I. A., Vakhrushev, I. V., Antonov, E. N., Yarygin, K. N., and Subbot, A. M. (2017). Visualization of Mesenchymal Stromal Cells in 2Dand 3D-Cultures by Scanning Electron Microscopy with Lanthanide Contrasting. Bull Exp Biol Med.
Paino, F., La Noce, M., Giuliani, A., De Rosa, A., Mazzoni, S., Laino, L., Amler, E., Papaccio, G., Desiderio, V., and Tirino, V. (2017). hDPSCs fabricate a vascularised woven bone tissue: a new tool in bone tissue engineering. Clin Sci (Lond).
Penfornis, P., Vallabhaneni, K. C., Janorkar, A. V., and Pochampally, R. R. (2017). Three dimensional tumor models for cancer studies. Front Biosci (Elite Ed) 9, 162-173.
Santo, V. E., Rebelo, S. P., Estrada, M. F., Alves, P. M., Boghaert, E., and Brito, C. (2017). Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J 12.
Sittadjody, S., Saul, J. M., and Opara, E. C. (2017). Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules. Methods Mol Biol 1479, 225-235.
Wang, S., Ghezzi, C. E., Gomes, R., Pollard, R. E., Funderburgh, J. L., and Kaplan, D. L. (2017). In vitro 3D corneal tissue model with epithelium, stroma, and innervation. Biomaterials 112, 1-9.
Xue, C., Xie, J., Zhao, D., Lin, S., Zhou, T., Shi, S., Shao, X., Lin, Y., Zhu, B., and Cai, X. (2017). The JAK/STAT3 signalling pathway regulated angiogenesis in an endothelial cell/adipose-derived stromal cell co-culture, 3D gel model. Cell Prolif 50.
Yang, G., Long, H., Ren, X., Ma, K., Xiao, Z., Wang, Y., and Guo, Y. (2017). Regulation of adipose-tissue-derived stromal cell orientation and motility in 2D- and 3D-cultures by direct-current electrical field. Dev Growth Differ.
Cancer/Tumor
Abe, T., Ohuchida, K., Koikawa, K., Endo, S., Okumura, T., Sada, M., Horioka, K., Zheng, B., Moriyama, T., Nakata, K., et al. (2017). Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination. Int J Oncol 50, 457-467.
Adak, A., Das, G., Barman, S., Mohapatra, S., Bhunia, D., Jana, B., and Ghosh, S. (2017). Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug. ACS Appl Mater Interfaces 9, 5067-5076.
Amoedo, N. D., Obre, E., and Rossignol, R. (2017). Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy. Biochim Biophys Acta.
Angiolini, V. A., Cruz, C. U., Lopez, M. L., Simon, L., and Matte, U. (2017). Alginate-embedded HuH-7 cells increase MMP-9 and reduce OCLN expression in vitro. Cancer Cell Int 17, 5.
Angioni, M. M., Bellofatto, K., Merlin, S., Menegon, S., Perra, A., Petrelli, A., Sulas, P., Giordano, S., Columbano, A., and Follenzi, A. (2017). A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis. Oncotarget.
Backer, A., Erhardt, O., Wietbrock, L., Schel, N., Goppert, B., Dirschka, M., Abaffy, P., Sollich, T., Cecilia, A., and Gruhl, F. J. (2017). Silk scaffolds connected with different naturally occurring biomaterials for prostate cancer cell cultivation in 3D. Biopolymers 107, 70-79.
Bouchet, B. P., and Akhmanova, A. (2017). Microtubules in 3D cell motility. J Cell Sci 130, 39-50.
Brancato, V., Comunanza, V., Imparato, G., Cora, D., Urciuolo, F., Noghero, A., Bussolino, F., and Netti, P. A. (2017). Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer. Acta Biomater 49, 152-166.
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Cepeda, M. A., Evered, C. L., Pelling, J. J., and Damjanovski, S. (2017a). Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels. J Cell Commun Signal.
Cepeda, M. A., Pelling, J. J., Evered, C. L., Leong, H. S., and Damjanovski, S. (2017b). The cytoplasmic domain of MT1-MMP is dispensable for migration augmentation but necessary to mediate viability of MCF-7 breast cancer cells. Exp Cell Res 350, 169-183.
Cheong, J. G., Song, D. G., Song, H. E., Berditchevski, F., Nam, S. H., Jung, J. W., Kim, H. J., Kim, J. E., Kim, S., Ryu, J., et al. (2017). Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment. Oncotarget.
Chioni, A. M., Bajwa, R. T., and Grose, R. (2017). 3D Organotypic Culture Model to Study Components of ERK Signaling. Methods Mol Biol 1487, 255-267.
Franco-Barraza, J., Francescone, R., Luong, T., Shah, N., Madhani, R., Cukierman, G., Dulaimi, E., Devarajan, K., Egleston, B. L., Nicolas, E., et al. (2017). Matrix-regulated integrin alphavbeta5 maintains alpha5beta1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife 6.
Fuzer, A. M., Lee, S. Y., Mott, J. D., and Cominetti, M. R. (2017). [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. J Cell Biochem.
Gao, Q., Wang, Z. C., Duan, M., Lin, Y. H., Zhou, X. Y., Worthley, D. L., Wang, X. Y., Niu, G., Xia, Y., Deng, M., et al. (2017a). Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. Gastroenterology 152, 232-242.e234.
Gao, X. L., Wu, J. S., Cao, M. X., Gao, S. Y., Cen, X., Jiang, Y. P., Wang, S. S., Tang, Y. J., Chen, Q. M., Liang, X. H., and Tang, Y. (2017b). Cytokeratin-14 contributes to collective invasion of salivary adenoid cystic carcinoma. PLoS One 12, e0171341.
Gimenez, A., Uriarte, J. J., Vieyra, J., Navajas, D., and Alcaraz, J. (2017). Elastic properties of hydrogels and decellularized tissue sections used in mechanobiology studies probed by atomic force microscopy. Microsc Res Tech 80, 85-96.
Halfter, K., and Mayer, B. (2017). Bringing 3D tumor models to the clinic - predictive value for personalized medicine. Biotechnol J.
He, X., and Toth, T. L. (2017). In vitro culture of ovarian follicles from Peromyscus. Semin Cell Dev Biol 61, 140-149.
Hernandez-Fernaud, J. R., Ruengeler, E., Casazza, A., Neilson, L. J., Pulleine, E., Santi, A., Ismail, S., Lilla, S., Dhayade, S., MacPherson, I. R., et al. (2017). Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nat Commun 8, 14206.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Ivanov, D. P., and Grabowska, A. M. (2017). Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D. Sci Rep 7, 41160.
Kim, H. J., Kwon, S., Nam, S. H., Jung, J. W., Kang, M., Ryu, J., Kim, J. E., Cheong, J. G., Cho, C. Y., Kim, S., et al. (2017). Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments. Faseb j.
Koledova, Z., and Lu, P. (2017). A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol 1501, 217-231.
Koshkin, V., Ailles, L. E., Liu, G., and Krylov, S. N. (2017). Preservation of the 3D Phenotype Upon Dispersal of Cultured Cell Spheroids Into Monolayer Cultures. J Cell Biochem 118, 154-162.
Koumarianou, P., Gomez-Lopez, G., and Santisteban, P. (2017). Pax8 controls thyroid follicular polarity through cadherin-16. J Cell Sci 130, 219-231.
Li, L., Chen, J., Xiong, G., St Clair, D. K., Xu, W., and Xu, R. (2017a). Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. J Cell Sci 130, 190-202.
Li, R., Hebert, J. D., Lee, T. A., Xing, H., Boussommier-Calleja, A., Hynes, R. O., Lauffenburger, D. A., and Kamm, R. D. (2017b). Macrophage-Secreted TNFalpha and TGFbeta1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. Cancer Res 77, 279-290.
Lintz, M., Munoz, A., and Reinhart-King, C. A. (2017). The Mechanics of Single Cell and Collective Migration of Tumor Cells. J Biomech Eng 139.
Liu, J., Liu, K., Feng, L., Liu, Z., and Xu, L. (2017). Comparison of nanomedicine-based chemotherapy, photodynamic therapy and photothermal therapy using reduced graphene oxide for the model system. Biomater Sci 5, 331-340.
Liverani, C., La Manna, F., Groenewoud, A., Mercatali, L., Van Der Pluijm, G., Pieri, F., Cavaliere, D., De Vita, A., Spadazzi, C., Miserocchi, G., et al. (2017). Innovative approaches to establish and characterize primary cultures: an ex vivo 3D system and the zebrafish model. Biol Open 6, 133-140.
Martinez de Pinillos Bayona, A., Woodhams, J. H., Pye, H., Hamoudi, R. A., Moore, C. M., and MacRobert, A. J. (2017). Efficacy of photochemical internalisation using disulfonated chlorin and porphyrin photosensitisers: an in vitro study in 2D and 3D prostate cancer models. Cancer Lett.
Nakaoka, T., Saito, Y., Shimamoto, Y., Muramatsu, T., Kimura, M., Kanai, Y., and Saito, H. (2017). The cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids. Cancer Sci.
Penfornis, P., Vallabhaneni, K. C., Janorkar, A. V., and Pochampally, R. R. (2017). Three dimensional tumor models for cancer studies. Front Biosci (Elite Ed) 9, 162-173.
Perin, N., Bobanovic, K., Zlatar, I., Jelic, D., Kelava, V., Kostrun, S., Markovic, V. G., Brajsa, K., and Hranjec, M. (2017). Antiproliferative activity of amino substituted benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles explored by 2D and 3D cell culture system. Eur J Med Chem 125, 722-735.
Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., et al. (2017). EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol 10, 23.
Pompaiah, M., and Bartfeld, S. (2017). Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis. Curr Top Microbiol Immunol 400, 149-168.
Pradhan, S., Clary, J. M., Seliktar, D., and Lipke, E. A. (2017a). A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres. Biomaterials 115, 141-154.
Pradhan, S., Hassani, I., Seeto, W. J., and Lipke, E. A. (2017b). PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture. J Biomed Mater Res A 105, 236-252.
Qu, Y., Han, B., Gao, B., Bose, S., Gong, Y., Wawrowsky, K., Giuliano, A. E., Sareen, D., and Cui, X. (2017). Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports 8, 205-215.
Riedl, A., Schlederer, M., Pudelko, K., Stadler, M., Walter, S., Unterleuthner, D., Unger, C., Kramer, N., Hengstschlager, M., Kenner, L., et al. (2017). Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses. J Cell Sci 130, 203-218.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Saito, Y., Nakaoka, T., and Saito, H. (2017). A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response. Adv Protein Chem Struct Biol 106, 227-242.
Santo, V. E., Rebelo, S. P., Estrada, M. F., Alves, P. M., Boghaert, E., and Brito, C. (2017). Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J 12.
Shannon, S., Jia, D., Entersz, I., Beelen, P., Yu, M., Carcione, C., Carcione, J., Mahtabfar, A., Vaca, C., Weaver, M., et al. (2017). Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901. BMC Cancer 17, 121.
Sittadjody, S., Saul, J. M., and Opara, E. C. (2017). Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules. Methods Mol Biol 1479, 225-235.
Spencer, K. C., Sy, J. C., Falcon-Banchs, R., and Cima, M. J. (2017). A three dimensional in vitro glial scar model to investigate the local strain effects from micromotion around neural implants. Lab Chip.
Tang, X., Wang, X., Zhao, Y. Y., Curtis, J. M., and Brindley, D. N. (2017). Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-kappaB activation. Mol Cancer 16, 36.
Tokuda, E. Y., Jones, C. E., and Anseth, K. S. (2017). PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity. Integr Biol (Camb) 9, 76-87.
Totti, S., Vernardis, S. I., Meira, L., Perez-Mancera, P. A., Costello, E., Greenhalf, W., Palmer, D., Neoptolemos, J., Mantalaris, A., and Velliou, E. G. (2017). Designing a bio-inspired biomimetic in vitro system for the optimization of ex vivo studies of pancreatic cancer. Drug Discov Today.
Ukaji, T., Lin, Y., Okada, S., and Umezawa, K. (2017). Inhibition of MMP-2-mediated cellular invasion by NF-kappaB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis. Biochem Biophys Res Commun.
van den Brand, D., Massuger, L. F., Brock, R., and Verdurmen, W. P. (2017). Mimicking Tumors: Towards More Predictive In Vitro Models for Peptide- and Protein-Conjugated Drugs. Bioconjug Chem.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C., and Cress, A. E. (2017). A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci 130, 104-110.
Weltin, A., Hammer, S., Noor, F., Kaminski, Y., Kieninger, J., and Urban, G. A. (2017). Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Biosens Bioelectron 87, 941-948.
Yildiz-Ozturk, E., Gulce-Iz, S., Anil, M., and Yesil-Celiktas, O. (2017). Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture. Cytotechnology.
Zhang, W., Lee, W. Y., and Zilberberg, J. (2017). Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma. Methods Mol Biol 1513, 171-191.
Zhao, Y., Qiao, S., Shi, S., Yao, L., Hou, X., Li, C., Lin, F. H., Guo, K., Acharya, A., Chen, X., et al. (2017). Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS Appl Mater Interfaces.
Zuchowska, A., Kwapiszewska, K., Chudy, M., Dybko, A., and Brzozka, Z. (2017). Studies of anticancer drug cytotoxicity based on long-term HepG2 spheroid culture in a microfluidic system. Electrophoresis.
Screening
Alessandri, K., Andrique, L., Feyeux, M., Bikfalvi, A., Nassoy, P., and Recher, G. (2017). All-in-one 3D printed microscopy chamber for multidimensional imaging, the UniverSlide. Sci Rep 7, 42378.
Amoedo, N. D., Obre, E., and Rossignol, R. (2017). Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy. Biochim Biophys Acta.
Brancato, V., Comunanza, V., Imparato, G., Cora, D., Urciuolo, F., Noghero, A., Bussolino, F., and Netti, P. A. (2017). Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer. Acta Biomater 49, 152-166.
Casey, J., Yue, X., Nguyen, D., Acun, A., Zellmer, V., Zhang, S., and Zorlutuna, P. (2017). 3D Hydrogel-Based Microwell Arrays As A Tumor Microenvironment Model To Study Breast Cancer Growth. Biomed Mater.
Cevenini, L., Calabretta, M. M., Lopreside, A., Branchini, B. R., Southworth, T. L., Michelini, E., and Roda, A. (2017). Bioluminescence Imaging of Spheroids for High-throughput Longitudinal Studies on 3D Cell Culture Models. Photochem Photobiol.
DeCicco RePass, M. A., Chen, Y., Lin, Y., Zhou, W., Kaplan, D. L., and Ward, H. D. (2017). Novel Bioengineered Three-Dimensional Human Intestinal Model for Long-Term Infection of Cryptosporidium parvum. Infect Immun 85.
Gao, Q., Wang, Z. C., Duan, M., Lin, Y. H., Zhou, X. Y., Worthley, D. L., Wang, X. Y., Niu, G., Xia, Y., Deng, M., et al. (2017). Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. Gastroenterology 152, 232-242.e234.
Halfter, K., and Mayer, B. (2017). Bringing 3D tumor models to the clinic - predictive value for personalized medicine. Biotechnol J.
Houshmand, M., Soleimani, M., Atashi, A., Saglio, G., Abdollahi, M., and Nikougoftar Zarif, M. (2017). Mimicking the Acute Myeloid Leukemia Niche for Molecular Study and Drug Screening. Tissue Eng Part C Methods.
Ishiguro, T., Ohata, H., Sato, A., Yamawaki, K., Enomoto, T., and Okamoto, K. (2017). Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications. Cancer Sci.
Ivanov, D. P., and Grabowska, A. M. (2017). Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D. Sci Rep 7, 41160.
Kostrzewski, T., Cornforth, T., Snow, S. A., Ouro-Gnao, L., Rowe, C., Large, E. M., and Hughes, D. J. (2017). Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease. World J Gastroenterol 23, 204-215.
Liang, J., Susan Sun, X., Yang, Z., and Cao, S. (2017). Anticancer Drug Camptothecin Test in 3D Hydrogel Networks with HeLa cells. Sci Rep 7, 37626.
Park, J., Lee, S. J., Chung, S., Lee, J. H., Kim, W. D., Lee, J. Y., and Park, S. A. (2017). Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation. Mater Sci Eng C Mater Biol Appl 71, 678-684.
Samavedi, S., Diaz-Rodriguez, P., Erndt-Marino, J. D., and Hahn, M. S. (2017). A Three-Dimensional Chondrocyte-Macrophage Coculture System to Probe Inflammation in Experimental Osteoarthritis. Tissue Eng Part A 23, 101-114.
Santo, V. E., Rebelo, S. P., Estrada, M. F., Alves, P. M., Boghaert, E., and Brito, C. (2017). Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J 12.
Siltanen, C., Diakataou, M., Lowen, J., Haque, A., Rahimian, A., Stybayeva, G., and Revzin, A. (2017). One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids. Acta Biomater.
Terrasso, A. P., Silva, A. C., Filipe, A., Pedroso, P., Ferreira, A. L., Alves, P. M., and Brito, C. (2017). Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds. J Pharmacol Toxicol Methods 83, 72-79.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Wang, S., Ghezzi, C. E., Gomes, R., Pollard, R. E., Funderburgh, J. L., and Kaplan, D. L. (2017). In vitro 3D corneal tissue model with epithelium, stroma, and innervation. Biomaterials 112, 1-9.
Weltin, A., Hammer, S., Noor, F., Kaminski, Y., Kieninger, J., and Urban, G. A. (2017). Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Biosens Bioelectron 87, 941-948.
Yildiz-Ozturk, E., Gulce-Iz, S., Anil, M., and Yesil-Celiktas, O. (2017). Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture. Cytotechnology.
Zhu, Z., and Yang, C. J. (2017). Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis. Acc Chem Res 50, 22-31.
3D Bioprinting
Bendtsen, S. T., Quinnell, S. P., and Wei, M. (2017). Development of a novel alginate-polyvinyl alcohol-hydroxyapatite hydrogel for 3D bioprinting bone tissue engineered scaffolds. J Biomed Mater Res A.
Borovjagin, A. V., Ogle, B. M., Berry, J. L., and Zhang, J. (2017). From Microscale Devices to 3D Printing: Advances in Fabrication of 3D Cardiovascular Tissues. Circ Res 120, 150-165.
Ferraz, M. A., Henning, H. H., Costa, P. F., Malda, J., Melchels, F. P., Wubbolts, R., Stout, T. A., Vos, P. L., and Gadella, B. M. (2017). Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation. Lab Chip.
Gao, G., Zhang, X. F., Hubbell, K., and Cui, X. (2017). NR2F2 regulates chondrogenesis of human mesenchymal stem cells in bioprinted cartilage. Biotechnol Bioeng 114, 208-216.
Henriksson, I., Gatenholm, P., and Hagg, D. A. (2017). Increased lipid accumulation and adipogenic gene expression of adipocytes in 3D bioprinted nanocellulose scaffolds. Biofabrication 9, 015022.
Jeon, H., Kang, K., Park, S. A., Kim, W. D., Paik, S. S., Lee, S. H., Jeong, J., and Choi, D. (2017). Generation of Multilayered 3D Structures of HepG2 Cells Using a Bio-printing Technique. Gut Liver 11, 121-128.
Park, J., Lee, S. J., Chung, S., Lee, J. H., Kim, W. D., Lee, J. Y., and Park, S. A. (2017). Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation. Mater Sci Eng C Mater Biol Appl 71, 678-684.
Schneeberger, K., Spee, B., Costa, P., Sachs, N., Clevers, H., and Malda, J. (2017). Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? Biofabrication.
Shukla, M. R., Singh, A. S., Piunno, K., Saxena, P. K., and Jones, A. M. (2017). Application of 3D printing to prototype and develop novel plant tissue culture systems. Plant Methods 13, 6.
Vanderburgh, J., Sterling, J. A., and Guelcher, S. A. (2017). 3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening. Ann Biomed Eng 45, 164-179.
Imaging
Alessandri, K., Andrique, L., Feyeux, M., Bikfalvi, A., Nassoy, P., and Recher, G. (2017). All-in-one 3D printed microscopy chamber for multidimensional imaging, the UniverSlide. Sci Rep 7, 42378.
Amoedo, N. D., Obre, E., and Rossignol, R. (2017). Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy. Biochim Biophys Acta.
Cecilia, A., Baecker, A., Hamann, E., Rack, A., van de Kamp, T., Gruhl, F. J., Hofmann, R., Moosmann, J., Hahn, S., Kashef, J., et al. (2017). Optimizing structural and mechanical properties of cryogel scaffolds for use in prostate cancer cell culturing. Mater Sci Eng C Mater Biol Appl 71, 465-472.
Cevenini, L., Calabretta, M. M., Lopreside, A., Branchini, B. R., Southworth, T. L., Michelini, E., and Roda, A. (2017). Bioluminescence Imaging of Spheroids for High-throughput Longitudinal Studies on 3D Cell Culture Models. Photochem Photobiol.
Ferraz, M. A., Henning, H. H., Costa, P. F., Malda, J., Melchels, F. P., Wubbolts, R., Stout, T. A., Vos, P. L., and Gadella, B. M. (2017). Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation. Lab Chip.
Fremont, S., and Echard, A. (2017). Studying cytokinesis and midbody remnants using correlative light/scanning EM. Methods Cell Biol 137, 239-251.
Gajewska, M., and McNally, S. (2017). Using 3D Culture of Primary Mammary Epithelial Cells to Define Molecular Entities Required for Acinus Formation: Analyzing MAP Kinase Phosphatases. Methods Mol Biol 1501, 199-216.
Ganesan, M. K., Finsterwalder, R., Leb, H., Resch, U., Neumuller, K., de Martin, R., and Petzelbauer, P. (2017). Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells. Tissue Eng Part C Methods 23, 38-49.
Imig, C., and Cooper, B. H. (2017). 3D Analysis of Synaptic Ultrastructure in Organotypic Hippocampal Slice Culture by High-Pressure Freezing and Electron Tomography. Methods Mol Biol 1538, 215-231.
Ivanov, D. P., and Grabowska, A. M. (2017). Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D. Sci Rep 7, 41160.
Knight, V. B., and Serrano, E. E. (2017). Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PeerJ 5, e2829.
Lakner, P. H., Monaghan, M. G., Moller, Y., Olayioye, M. A., and Schenke-Layland, K. (2017). Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models. Sci Rep 7, 42730.
Li, X., Brooks, J. C., Hu, J., Ford, K. I., and Easley, C. J. (2017). 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17, 341-349.
Novikov, I. A., Vakhrushev, I. V., Antonov, E. N., Yarygin, K. N., and Subbot, A. M. (2017). Visualization of Mesenchymal Stromal Cells in 2Dand 3D-Cultures by Scanning Electron Microscopy with Lanthanide Contrasting. Bull Exp Biol Med.
Regmi, S., Cao, J., Pathak, S., Gupta, B., Kumar Poudel, B., Tung, P. T., Yook, S., Park, J. B., Yong, C. S., Kim, J. O., et al. (2017). A three-dimensional assemblage of gingiva-derived mesenchymal stem cells and NO-releasing microspheres for improved differentiation. Int J Pharm 520, 163-172.
Romero-Lopez, M., Trinh, A. L., Sobrino, A., Hatch, M. M., Keating, M. T., Fimbres, C., Lewis, D. E., Gershon, P. D., Botvinick, E. L., Digman, M., et al. (2017). Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials 116, 118-129.
Russell, M. R., Lerner, T. R., Burden, J. J., Nkwe, D. O., Pelchen-Matthews, A., Domart, M. C., Durgan, J., Weston, A., Jones, M. L., Peddie, C. J., et al. (2017). 3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy. J Cell Sci 130, 278-291.
Santo, V. E., Rebelo, S. P., Estrada, M. F., Alves, P. M., Boghaert, E., and Brito, C. (2017). Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J 12.
Short, A. R., Czeisler, C., Stocker, B., Cole, S., Otero, J. J., and Winter, J. O. (2017). Imaging Cell-Matrix Interactions in 3D Collagen Hydrogel Culture Systems. Macromol Biosci.
3D in Meetings
Keystone Symposia - Engineered Cells and Tissues as Platforms for Discovery and Therapy
Date: 9th to12th March 2017
Location: Boston, Massachusetts, United States
Website: https://www.keystonesymposia.org/17K1
Contact: Phone: 1 800-253-0685; Email: info@keystonesymposia.org
Organized by: Keystone Symposium
Cell Culture World Congress USA 2017
Date: 23rd to 24th May 2017
Location: San Diego, California, United States
Website: http://go.evvnt.com/68105-0
Contact person: Freya Smale
This event allows research scientists engaged in upstream and downstream bioprocessing to discuss novel techniques and techniques and technologies.
Organized by: Terrapinn USA
3rd Annual 3D Cellular Models: Engineering Predictive Preclinical Screening Models
Date: 14th to 15th June 2017
Location: Boston, Massachusetts, United States
Website: http://www.worldpreclinicalcongress.com/3D-Cellular-Models/
Organized by Cambridge Healthtech Institute
The 2nd International Conference "Plant Cells In Vitro: Fundamentals and Applications"
Date: 26th to 27th June 2017
Location: Vienna, Austria
Website: http://viscea.org/index.php/plant-in-vitro
Contact person: Alisher Touraev
The Conference will discuss wide range of modern in vitro plant cell and organ culture technologies, fundamental aspects of plant cell totipotency, differentiation, regeneration, embryogeneisis, and practical applications of in vitro technologies.
Organized by: Vienna International Science Conferences & Events Association (VISCEA)