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BME 695L Lecture 2: Designing Nanomedical Systems
Online Presentations | 31 Aug 2011 | Contributor(s):: James Leary
See references below for related reading.2.1 Elements of good engineering design2.1.1 Whenever possible, use a general design that has already been tested2.1.2 Whenever possible, take advantage of “biomimicry” –...
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Nano*High: Looking for the Good News in Your Genome: Personalized Medicine--Science and Ethics
Online Presentations | 31 Jan 2011 | Contributor(s):: Jasper Rine
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Nano*High: Nature's Nasty Nanomachines: How Viruses Work, and How We Can Stop Them
Online Presentations | 25 Sep 2010 | Contributor(s):: Carolyn R. Bertozzi
The birth and growth of nanotechnology is only a few decades old, whereas Nature has been building nano-machines for millennia. Viruses are marvels of natural nano-engineering, but can pose a problem for human health. To combat these nano-machines, scientists are turning to recent developments...
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Nanomedicine – How Can Something so Small be so Huge for the Future of Healthcare?
Online Presentations | 17 Jun 2010 | Contributor(s):: James Leary
Dr. James Leary discusses the future on medicine and the impact nanotechnology will have on healthcare.
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Optical BioMEMS Microfluidic Technologies for Hand-Held, Point-of-Care, Medical Devices
Online Presentations | 23 Nov 2009 | Contributor(s):: James Leary
Portable, point-of-care, medical diagnostic devices could provide an important new component in more cost-effective healthcare delivery. Rapid measurements of blood samples during an examination within a doctor’s office or in the field, could allow immediate appropriate treatment of medical...
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History of Research with Human Subjects: Ethical Steps Forward and Back
Online Presentations | 29 Apr 2009 | Contributor(s):: Jason T. Eberl
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"Who Owns Truth?" - Biomedical Research in a Health Policy Context
Online Presentations | 30 Mar 2009 | Contributor(s):: Samuel A. Richmond
This presentation examines a claim made by PhRMA on behalf of pharmaceutical manufacturing companies of America, and the response of the International Committee of Medical Journal Editors (ICMJE) questioning drug company publication policies and practices. Also considered are changes in law...
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Nanomaterials for Bone & Neural Tissue Engineering
Online Presentations | 11 Sep 2008 | Contributor(s):: S. Swaminathan
Tissue engineering is defined as “the application of biological, chemical and engineering principles towards the repair, restoration or regeneration of tissues using scaffolds, cells, factors alone or in combination.” The goal lis to design and develop biodegradable, biocompatible polymer-ceramic...
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Use of Ceramic based biomaterials for their application in vitro osteogenic differentiation
Online Presentations | 30 Jul 2008 | Contributor(s):: Gopal Pande
The use of bioceramics for preparation of implants and prosthesis for applications in orthopedic surgery has been done over several years. Recently new formulations for making substrates and coatings using ceramic material such as alumina, bioglass or zirconia have been done for improved...
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<i>In Vivo</i> Nuclear Magnetic Resonance Imaging and Spectroscopic Investigations of Structure and Function of Rodent Brain
Online Presentations | 30 Jul 2008 | Contributor(s):: Anant B. Patel
Nuclear Magnetic Resonance Imaging (MRI) is a powerful and a versatile imaging modality for non-invasive characterization of host structure and function. MRI has grown in many directions such as functional MRI, diffusion tensor imaging, chemical shift imaging, which is used to detect single cells...
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Quality by Design and Process Analytical Technology for Pharmaceutical Manufacturing in the 21st Century
Online Presentations | 21 Jul 2008 | Contributor(s):: Stephen R. Byrn
PAT or Process Analytical Technology is an initiative and guidance from the U.S. FDA to encourage modernization of pharmaceutical manufacturing. In reality, PAT is a subset of the larger concept of Quality by Design which is the implementation of design concepts for pharmaceutical dosage forms...
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Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations
Online Presentations | 21 Jul 2008 | Contributor(s):: Stephen R. Byrn
Nanoparticles hold great promise for drug delivery applications. Several polymer-based formulations containing nanoparticles are in late phase development or on the market. In fact, polymer dispersions provide one of the best methods to prepare nanoparticles of small-molecule organic drugs....
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Multiplex Detection of Cell Surface Markers using Plasmonic Sensors
Online Presentations | 21 Jul 2008 | Contributor(s):: Joseph M K Irudayaraj
Gold nanorod molecular probes (GNrMPs) were designed and fabricated for multiplex identification of cell surface markers in HBECs. Cells were probed directly using dark field microscopy integrated with a spectral imager for simultaneous detection of up to three surface markers. The...
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Development of Highly Porous Large Polymeric Microparticles for Sustained Local Drug Delivery to the Lung
Online Presentations | 10 Jul 2008 | Contributor(s):: Yoon Yeo
In this presentation, I will introduce a new way of making highly porous large polymeric microparticles recently developed in my lab. These microparticles exhibited desirable aerodynamic properties, reduced macrophage uptake, encapsulated a drug efficiently, and provided sustained drug release...
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Discovery Park at Purdue University: Engine for Academic and Commercial Growth
Online Presentations | 10 Jul 2008 | Contributor(s):: Charles Buck, Pankaj Sharma
The Bindley Bioscience Center and Birck Nanotechnology Center at Discovery Park blend life sciences and engineering research to cultivate and support innovative, multi-investigator, interdisciplinary research teams. Discovery Park engages researchers in a broader perspective with applications of...
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Pharmaceutical Manufacturing – Present and Future and What Should be the Role of India?
Online Presentations | 10 Jul 2008 | Contributor(s):: Prabir K. Basu
Pharmaceutical manufacturing is at a crossroads. There is widespread realization among the regulators and the industry that the current state of high variability and “Quality by Inspection” is no longer adequate. While the industry still largely employs first generation quality management tools,...
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Design of Multi-Component, Multi-Functional Nanomedical Systems for Drug/Gene Delivery and Theragnostics
Online Presentations | 02 Jul 2008 | Contributor(s):: James Leary
Multi-component and multifunctional nanoparticles hold great promise for drug/gene delivery and simultaneous diagnostics and therapeutics ("theragnostics"). Sophisticated multi-component systems can employ collections of specialized molecules in a nanodelivery system whose actions can be...
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High-Aspect-Ratio Micromachining of Titanium: Enabling New Functionality and Opportunity in Micromechanical Systems Through Greater Materials Selection
Online Presentations | 18 Jun 2008 | Contributor(s):: Masa Rao
Traditionally, materials selection has been limited in high-aspect-ratio micromechanical applications, due primarily to the predominance of microfabrication processes and infrastructure dedicated to silicon. While silicon has proven to be an excellent material for many of these applications, no...
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BNC Research Review: Carbon Nanotubes as Nucleic Acid Carriers
Online Presentations | 04 Jun 2008 | Contributor(s):: Don Bergstrom
This presentation is part of a collection of presentations describing the projects, people, and capabilities enhanced by research performed in the Birck Center, and a look at plans for the upcoming year.
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BNC Research Review: The Birck Nanotechnology Center-Progress, Opportunitiees, and Challenges
Online Presentations | 04 Jun 2008 | Contributor(s):: Timothy D. Sands
This presentation is part of a collection of presentations describing the projects, people, and capabilities enhanced by research performed in the Birck Center, and a look at plans for the upcoming year.