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Analyzing Tensile Strength and Fracture Behavior in MCC and Lactose Composite Tablets
27 Feb 2019 | | Contributor(s):: Melanie Hacopian, Marcial Gonzalez, Isabel Bojanini, Vidal Lopez, Jesse Lee Hoffman, Caroline Baker
Tablets containing various compositions of MCC and Lactose at several relative densities were subjected to fracture and analyzed for tensile strength. Results showed that as the mass fraction of Lactose increased, tensile strength and fracture strength decreased. Analyzing the tensile strength...
Micelles - Drug Delivery Lab
04 Jan 2017 | | Contributor(s):: SHINE Project, SHINE Project
This lab consists of activities designed to teach students about how nanotechnology can be used to transport medicine for targeted drug delivery. The entire bundle can be downloaded by clicking on the download link in the upper right or compontents can be individually downloaded by visiting the...
[Illinois] Nanotechnology meets Biology in the Cancer Cell: Applications in Medicine, Drug Delivery, and Determining Drug Efficacy
04 Feb 2016 | | Contributor(s):: Mostafa El-Sayed
[Illinois] Microcapsules for Luminescent Tracking and Controlled Drug Delivery
16 Dec 2013 | | Contributor(s):: Yulia Maximenko
Polyelectrolyte microcapsules are formed on porous calcium carbonate templates that are impregnated and coated with 2.9 nanometer luminescent silicon nanoparticles. The complexes are characterized in suspension as well as in thin films using fluorescence microscopy, optical microscopy, and x-ray...
A CNTFET-Based Nanowired Induction Two-Way Transducers
05 Sep 2012 | | Contributor(s):: Rostyslav Sklyar
A complex of the induction magnetic field two-way nanotransducers of the different physical values for both the external and implantable interfaces in a wide range of arrays are summarized. Implementation of the nanowires allows reliable transducing of the biosignals' partials and bringing of...
The Importance of Zeta Potential for Drug/Gene Delivery in Nanomedicine
11 Apr 2012 | | Contributor(s):: James Leary
Malvern Instruments Workshop: Nano-particle Characterization Symposium
The key focus of the symposium is to demonstrate how different analytical techniques provide the information needed to advance nanotechnology.
KIST/PU Theragnosis – A New Paradigm of Personalized Medicine
06 Dec 2011 | | Contributor(s):: Ick Chan Kwon
Companion Diagnosis, based on pharmacogenomics, has been recognized as one of most important key representatives of personalized medicine. However, Companion Diagnosis does not provide any clues in developing new ways of therapeutics but it only provides a best choice of drugs based on given...
Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy
05 Dec 2011 | | Contributor(s):: Li Tang
Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer treatment. The size of these drug delivery vehicles has been strongly correlated with their in...
BME 695L Special Lecture 3: In vivo Model Systems to Study Nanomedical Approaches to Cancer Detection and Intervention
02 Dec 2011 | | Contributor(s):: Deborah W Knapp
Guest lecturer: Deborah Knapp.
BME 695L Lecture 15: GMP and Issues of Quality Control Manufacture of Nanodelivery Systems
02 Dec 2011 | | Contributor(s):: James Leary
See references below for related reading.15.1 Overview15.1.1 What does cGMP mean?15.1.2 Why GMP? Controlling processes means more predictable...
BME 695L Lecture 12: Assessing Drug Efficacy and Nanotoxicity at the Single Cell Level
22 Nov 2011 | | Contributor(s):: James Leary
See references below for related reading.12.1 Introduction to measures of efficacy for nanomedicine12.1.1 for evaluation purposes, does structure/size reveal function?12.1.2 nanomedical treatment at the single cell...
BME 695L Lecture 13: Designing Nanomedical Systems (NMS) for In-vivo Use
See references below for related reading.13.1 Bringing in-vivo considerations into NMS design13.1.1 the in-vitro to ex-vivo to in-vivo paradigm 220.127.116.11 In-vitro - importance of choosing...
BME 695L Lecture 14: Designing and Testing Integrated Nanomedical Systems
See references below for related reading.14.1 Introduction to integrated designs14.1.1 “Total design” but there is some order in the design process14.1.2 A brief outline of the total design...
BME 695L Lecture 11: Assessing Nanotoxicity at the Single Cell Level
27 Oct 2011 | | Contributor(s):: James Leary
See references below for related reading.11.1 Need for single cell measures of nanotoxicity11.1.1 There is more than one way for a cell to die...11.1.2 "Necrosis" vs. "Apoptosis"11.1.3 There...
BME 695L Lecture 10: Nanodelivery of Therapeutic Genes and Molecular Biosensor Feedback Control Systems
26 Oct 2011 | | Contributor(s):: James Leary
See references below for related reading.10.1 Introduction and overview10.1.1 Some of the advantages of therapeutic genes10.1.2 Some of the advantages of molecular biosensor feedback control...
BME 695L Lecture 9: Challenges of Proper Drug Dosing with Nanodelivery Systems
19 Oct 2011 | | Contributor(s):: James Leary
See references below for related reading.9.1 Overview of drug dosing problem9.1.1 Problems of scaling up doses from animal systems9.1.2 Basing dosing on size, area, weight of...
BME 695L: Engineering Nanomedical Systems
31 Aug 2011 | | Contributor(s):: James Leary
This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell targeting strategies, choice of core nanomaterials, technologies for testing composition and structure...
Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations
out of 5 stars
21 Jul 2008 | | Contributor(s):: Stephen R. Byrn
Nanoparticles hold great promise for drug delivery applications. Several polymer-based formulations containing nanoparticles are in late phase development or on the market. In fact, polymer dispersions provide one of the best methods to prepare nanoparticles of small-molecule organic drugs....
Development of Highly Porous Large Polymeric Microparticles for Sustained Local Drug Delivery to the Lung
10 Jul 2008 | | Contributor(s):: Yoon Yeo
In this presentation, I will introduce a new way of making highly porous large polymeric microparticles recently developed in my lab. These microparticles exhibited desirable aerodynamic properties, reduced macrophage uptake, encapsulated a drug efficiently, and provided sustained drug release...