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Using Mass Spectrometry to Understand Membrane Organization
28 Mar 2008 | | Contributor(s):: Mary Kraft
Our ability to engineer tissues and biomimetic devices hinges upon an understanding of the structure-function relationship in healthy and diseased cells. Our laboratory utilizes materials characterization, quantitative engineering principles, cell biology and chemistry to elucidate the influence...
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Silicon nanomembranes
30 Mar 2008 | | Contributor(s):: Max Lagally
Silicon nanomembranes are extremely thin (
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Ion Selectivity in Synthetic and Natural Channels
31 Mar 2008 | | Contributor(s):: Susan Rempe
Transport across membranes and nanopores can be characterized by static equilibrium properties as well as by nonequilibrium dynamic properties. For example, equilibrium selectivity properties of a nanopore can be characterized by the difference in interaction free energy for transferring one ion...
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Modeling (Semi) Unstructured Proteins
26 Mar 2008 | | Contributor(s):: Michael Colvin
The past century has seen tremendous progress in determining the biochemical and biophysical processes that constitute life. One exciting consequence of this understanding is the possibility of developing mathematical models of biological function that are accurate and even predictive. My...
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Controlling Membrane Organization: Effects of pH, Ions, and composition
23 Mar 2008 | | Contributor(s):: Jennifer Hovis
Our main research interests are in determining, at the molecular level, how cell membranes are organized and how that organization relates to function. The primary molecular building blocks of cell membranes are lipids, amphipathic molecules that assemble into two opposed leaflets forming a...
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The Functional Protocell concept
23 Mar 2008 | | Contributor(s):: Eric Jakobsson
We have invented and created the first prototype of the Functional Protocell.We define the “functional protocell" as a nanoporous solid surrounded by a membrane. The cavities in the solid can be filled with any desired electrolyte up to the limit of solubility. The surrounding membrane can...
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Spectroscopy and Modeling to Infer Channel Structure and Function
23 Mar 2008 | | Contributor(s):: Vishwanath Jogini
We are particularly interested in issues about ion permeation, ion selectivity, gating, and channel inhibitors. We are currently working on the KcsA channel, the OmpF porin, and the gramicidin A> channel. We are also spending our efforts in the development of new computational approaches for...
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biomoca
30 May 2006 | | Contributor(s):: Reza Toghraee, Umberto Ravaioli
Ion channel simulator
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Quantum and Semi-classical Electrostatics Simulation of SOI Trigates
19 Feb 2008 | | Contributor(s):: Hyung-Seok Hahm, Andres Godoy
Generate quantum/semi-classical electrostatic simulation results for a simple Trigate structure
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CAD of MEMS & NEMS: State of the Art & Future Challenges
24 Feb 2008 | | Contributor(s):: Andreas Cangellaris
Computer aided design environments are very mature and used extensively for the design of every integrated electronical component that is commercially available to all of us. This presentation reviews recent developments in taking that framework and making it pertinent to the design of systems...
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Lecture 3: Nucleic Acids, RNA, and Proteins
11 Feb 2008 | | Contributor(s):: Paul R Selvin
Nucleic Acids, Proteins, DNA Dimensions and Stability, How to make a nucleotide
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Illinois Tools: NanoGromacs
27 Feb 2008 | | Contributor(s):: Dairui Chen, Derrick Kearney, Jay Mashl, Nahil Sobh, Eric Jakobsson
Implementation of the popular molecular dynamics software suite GROMACS
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BioMOCA Suite
04 Feb 2008 | | Contributor(s):: David Papke, Reza Toghraee, Umberto Ravaioli, Ankit Raj
Simulates ion flow through a channel.
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Ferroelectric BaTiO3 Nanowires: Synthesis, Properties, and Device Applications
12 Feb 2008 | | Contributor(s):: Zhaoyu Wang
One dimensional ferroelectric nanowires have attracted much attention due to its interests in fundamental physics and potential applications in Nanoelectromechanical Systems (NEMS), non-volatile ferroelectric memories, and sensors. Domain structure is the most important property of ferroelectric...