Ji-Xin Cheng was born in Jixi, Anhui, P.R. China in 1971. He attended University of Science and Technology of China (USTC) and received a Guo MoRuo Prize, the highest award for undergraduates at USTC. His PhD study, under the supervision of Prof. Qingshi Zhu at USTC, was awarded with President Special Scholarship. As a graduate student, he worked as a research assistant at Universite Paris-sud and the Hong Kong University of Science and Technology (HKUST). After the first postdoc training with Prof. Yijing Yan at HKUST, Cheng joined Prof. Sunney Xie’s group at Harvard University as a postdoctoral fellow in 2000. There he devoted himself to the development of coherent anti-Stokes Raman scattering (CARS) microscopy that permits high-sensitivity vibrational imaging with 3D spatial resolution. He shares two patents with his colleagues for the invention of CARS microscopy. In 2003, Cheng moved to Purdue University as an assistant professor in Weldon School of Biomedical Engineering. There Cheng has built a multidisciplinary and collaborative research program that includes membrane and cell biophysics, nonlinear optical imaging, and nanomedicine development. Cheng also designed a Biomedical Optics course offered every fall semester at Purdue University. He is the co-organizer of a biennial symposium focused on nonlinear optical spectroscopy and microscopy in the American Chemistry Society national meetings.