Cell Factory for Small Molecule Inducible Delivery of Low Dose IL-2
31 Aug 2023 | | Contributor(s):: Celsa Pachlhofer, Yafet Arefeayne, Rice University
Autoimmune and inflammatory diseases are characterized by insufficient regulatory T cells (Treg), which play a central role in maintaining peripheral tolerance, preventing autoimmunity, and limiting chronic inflammation. Treg cells depend on IL-2 for survival and maintenance of their...
Jun 09 2023
Exploring the Nano World: Building Nanoscale Structures with Polymer Modeler
DNA Automation with Nano-Structured Ceramics
03 Jan 2023 | | Contributor(s):: NACK Network
We will discuss how the use of nano-structured ceramic films enables the synthesis of hundreds of DNA genes in gram quantities overnight. Furthermore, we will describe how these nano-structured ceramics can be manufactured without the use of expensive, currently highly backlogged, nanofabs...
12 Oct 2022 | | Contributor(s):: Fatma Pri-Cakmak, NACK Network
Engineer and Manufacture Off-the-Shelf CAR-Natural Killer Cells for Targeted
07 Oct 2022 | | Contributor(s):: Xiaoping Bao
Cancer is a major threat for humans worldwide, with over 18 million new cases and 9.6 million cancer-related deaths in 2018. Although most common cancer treatments include surgery, chemotherapy, and radiotherapy, unsatisfactory cure rates require new therapeutic approaches, particularly for...
Virtual Tissue Computer Simulation of Development, Homeostasis and Disease using CompuCell3D
22 Sep 2022 | | Contributor(s):: James A Glazier, Trinity Chung, The Micro Nano Technology - Education Center
Building & Testing a Component of Synthetic Genetic Circuit in Mammalian Cells
20 Aug 2022 | | Contributor(s):: Ariel Delos Reyes, Rice University
Oscillations in protein levels within cells help facilitate a variety of biological processes, from circadian rhythm to cell cycle progression. This research focuses on developing a platform for creating oscillatory circuits in mammalian cells by using several interrelated DNA constructs....
Nanotechnology: The Future of Medicine?
28 Jul 2022 | | Contributor(s):: Jared Ashcroft, The Micro Nano Technology - Education Center
Antibody Engineers - Antibody Hackathon
15 Jul 2022 | | Contributor(s):: Sandra Porter, The Micro Nano Technology - Education Center
Nanomedicine for Drug Delivery, Controlled Release and Targeted Therapy
17 Jun 2022 | | Contributor(s):: Neda Habibi, The Micro Nano Technology - Education Center
CompuCell3D - Simulation of cell crawling in 3D
03 Feb 2022 |
Deploys the CompuCell3D simulation of cell crawling in 3D by Fortuna et al. 2020 https://doi.org/10.1016/j.bpj.2020.04.024
Designing Machine Learning Surrogates for Molecular Dynamics Simulations
25 Nov 2021 | | Contributor(s):: JCS Kadupitiya
Molecular dynamics (MD) simulations accelerated by high-performance computing (HPC) methods are powerful tools for investigating and extracting the microscopic mechanisms characterizing the properties of soft materials such as self-assembled nanoparticles, virus capsids, confined electrolytes,...
Agent Based Active Matter Simulations with Mechanica
14 Nov 2021 | | Contributor(s):: Somogyi, Andy T
Mechanica is an interactive mesh-free, chemistry and biology simulation environment, with an emphasis towards enabling users to model and simulate complex sub-cellular and cellular biological physics problems. Mechanica is designed first and foremost to enable users to work interactively...
Fun Experiments You Can Only Do With Frogs
08 Jul 2021 | | Contributor(s):: Rebecca W. Heald
Our studies aim to reveal underlying principles of spindle assembly and biological size control, as well as the molecular basis of variation that contributes to genomic instability and evolution. This talk will focus on the nano-scale aspects and include some single molecule experiments our lab...
Rebecca W. Heald
Tuberculosis Model Incorporating Treatment, Vaccination, and Antibiotic Resistance
27 May 2021 | | Contributor(s):: Antonio Zdanis Neher
Run though an interactive application to learn more about the consequences of antibiotic resistant pathogens through the lens of Tuberculosis.
Cancer Evolution in CompuCell3D
27 May 2021 | | Contributor(s):: Juliano Ferrari Gianlupi, James A Glazier
Demonstrates implemetation of cancer evolution in CompuCell3D
FocalPointPlasticity Plugin Demo
19 May 2021 | | Contributor(s):: Juliano Ferrari Gianlupi, T.J. Sego
This simple demo shows basic functionality of FocalPointPlasticity and how link rigidity affects cell behaviors.
CompuCell3D - Chemotactic Elongation Demo
30 Mar 2021 | | Contributor(s):: Juliano Ferrari Gianlupi, T.J. Sego
Implementation of Developmental biology 289.1 (2006): 44-54. and PLoS Comput Biol 4.9 (2008): e1000163.
PhysiCell simulation of GBM tumour under oHSV1 treatment
28 Mar 2021 | | Contributor(s):: Adrianne Jenner, Randy Heiland, Paul Macklin
Simulation for GBM fragment growth under oHSV1 treatment published in Jenner et al. (2021)