PhysiCell aims to provide a robust, scalable code for simulating large systems of cells in 3-D tissues on standard desktop computers.
PhysiCell simulation of GBM tumour under oHSV1 treatment
28 Mar 2021 | Contributor(s):: Adrianne Jenner, Randy Heiland, Paul Macklin
Simulation for GBM fragment growth under oHSV1 treatment published in Jenner et al. (2021)
How Simple Cell-Cell Interactions Lead to Complex Multicellular Dynamics
04 Feb 2021 | | Contributor(s):: Paul Macklin
In this talk, we use agent-based simulation models to simulate (1) individual cell behaviors, (2) cell-cell interactions, and (3) cell-environment interactions to show how simple rules can give rise to complex multicellular phenomena. We showcase and explore free, interactive online tools to...
Biology of COVID-19 Attack on Epithelial Cells, understood from a Modeling and Simulation Perspective
n this session, we describe a community-driven effort to iteratively develop a multiscale, spatially-resolved open source model of SARS-CoV-2 dynamics and immune response in tissues.
PhysiCell 3D tumor
20 Jan 2021 | | Contributor(s):: Randy Heiland, Paul Macklin, Koudoro, Serge, Javier Guaje
Simulate a 3D spheroid cancer tumor with PhysiCell
Cycle Training App for PhysiCell
18 Dec 2020 | | Contributor(s):: Furkan Kurtoglu, Aneequa Sundus, Kali Nicole Konstantinopoulos, Drew Willis, Mary Chen, Randy Heiland, Paul Macklin
Training application for "Cycle" concept in PhysiCell.
Three-Type Multicellular Simulation Lab
09 Nov 2020 | | Contributor(s):: Paul Macklin, Randy Heiland
An analog of the 3-body problem: modeling 3 interacting cell types in a dynamic environment
PhysiBoSS simulation of COVID19 infection
27 Oct 2020 | | Contributor(s):: Vincent Noel, Miguel Ponce de Leon, Anna Niarakis, Laurence Calzone, Alfonso Valencia, Arnau Montagud
PhysiBoSS-COVID: the Boolean modelling of COVID-19 signalling pathways in a multicellular simulation framework
PhysiCell model for tumor hypoxia
07 Aug 2020 | | Contributor(s):: Lima Da Rocha, Heber, Paul Macklin, Furkan Kurtoglu
Multicellular simulation in 2-D of tumor hypoxia.
COVID-19 data analysis
07 Aug 2020 | | Contributor(s):: Randy Heiland, Paul Macklin
Perform data analysis in a Jupyter notebook using data from the pc4covid19 tool.
A virion pharmacodynamics response tissue simulator
27 Jul 2020 | | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin
Simulate virus pharmacodynamics response with PhysiCell
PhysiBoSSa: cell fate decision in TNF Boolean model
13 May 2020 | | Contributor(s):: Gerard Pradas, Arnau Montagud, Miguel Ponce de Leon
PhysiBoSSa model of the cell fate decision in TNF Boolean model in a multicellular multiscale system
PhysiBoSSa Simulation with ECM
20 Apr 2020 | | Contributor(s):: Marco Ruscone, Vincent Noel, Laurence Calzone, Gaelle Letort, Arnau Montagud
Agent based multicellular simulation with extracellular matrix interaction
A virion infected-cell response tissue simulator
13 Apr 2020 | | Contributor(s):: Yafei Wang, Randy Heiland, Paul Macklin
Simulate infected cell response to virus with PhysiCell
A virion replication tissue simulator
Simulate virus replication dynamics with PhysiCell
A virion endocytosis tissue simulator
Simulate virus endocytosis (internalization), ACE2 receptor dynamics with PhysiCell
PhysiCell model for COVID19
26 Mar 2020 | | Contributor(s):: Randy Heiland, Yafei Wang, Paul Macklin
Prototype 2-D multicellular simulation of COVID19.
Mechanics Training App for PhysiCell
14 Feb 2020 | | Contributor(s):: Aneequa Sundus, Furkan Kurtoglu, Mishler, Daniel S, Randy Heiland, Paul Macklin
Training application for "Mechanics" concept in PhysiCell.
PhysiCell model with SBML intracellular model
10 Feb 2020 | | Contributor(s):: Randy Heiland
Each cell will have its own intracellular (metabolic) model that will affect the microenvironment.
Volume Training App for PhysiCell
10 Feb 2020 | | Contributor(s):: Furkan Kurtoglu, Aneequa Sundus
Training application for "Volume" concept in PhysiCell.
pc4thanos : Thanos vs. Avengers multicellular demonstrator
31 Jan 2020 | | Contributor(s):: Paul Macklin
PhysiCell Thanos vs. Avengers demonstrator for multicellular simulation techniques