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Nanomaterials in Biosensing Using Ion Selective Field Effect Transistors and Metal Particles
30 Jul 2008 | | Contributor(s):: Nalam Madhusudhana Rao
The multifunctionality, multilayerable architechture and size of nanomaterials offer tremendous opportunities in developing sensing platforms. Ion Selective Field Effect Transistors (ISFET) are solid state and robust pH/ion sensing devices with excellent “voltage vs. ion concentration”...
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Nanocomposite-Modified Electrodes for Sensing Biological Analytes
30 Jul 2008 | | Contributor(s):: V. Yegnaraman
Electrochemical sensing of analytes is mostly enabled by transducers based on potentiometry and amperometry. In this, design of sensing (working) electrode is of utmost importance since it only decides the sensitivity and selectivity features of the sensor. Chemical modification of the electrode...
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Micro-fabricated Biosensors for Cardiac Diagnostics
30 Jul 2008 | | Contributor(s):: V.Ramgopal Rao
In this talk the current status of an ongoing effort in the Electrical Engineering Department at IIT Bombay on the development of an integrated systems to provide point-of-care diagnostic support for cardiovascular diseases will be presented. The system under development monitors the molecular...
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Self-association of peptides and proteins: Retrospect and prospects
30 Jul 2008 | | Contributor(s):: R. Nagaraj
The ability of peptides and proteins to form aggregates was known from the dawn of protein and peptide chemistry! It was often considered a nuisance and attention was directed towards disaggregating them to ensure dissolution particularly in aqueous solution. X-ray crystallography has indicated...
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Use of Ceramic based biomaterials for their application in vitro osteogenic differentiation
30 Jul 2008 | | Contributor(s):: Gopal Pande
The use of bioceramics for preparation of implants and prosthesis for applications in orthopedic surgery has been done over several years. Recently new formulations for making substrates and coatings using ceramic material such as alumina, bioglass or zirconia have been done for improved...
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<i>In Vivo</i> Nuclear Magnetic Resonance Imaging and Spectroscopic Investigations of Structure and Function of Rodent Brain
30 Jul 2008 | | Contributor(s):: Anant B. Patel
Nuclear Magnetic Resonance Imaging (MRI) is a powerful and a versatile imaging modality for non-invasive characterization of host structure and function. MRI has grown in many directions such as functional MRI, diffusion tensor imaging, chemical shift imaging, which is used to detect single cells...
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Nanohybrids as Sensors and Superstructures
30 Jul 2008 | | Contributor(s):: K. George Thomas
We have recently initiated a detailed research program on the design of nanoparticle conjugates of organic/inorganic molecules which enable the coupling of the intrinsic functionalities of molecular systems (binding, self-assembly, switching etc.) with the size and shape dependent optoelectronic...
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Nanobiotechnology – a different perspective
22 Jul 2008 | | Contributor(s):: Murali Sastry
The study of the synthesis, exotic properties, assembly/packaging and potential commercial application of nanomaterials is an extremely important topic of research that is expected to have far-reaching global impact. The focus of my talk will be on an emerging branch of nanotechnology that...
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Transforming Pharmaceutical Manufacturing in the 21st Century – Indiana as a Center for Biopharmaceutical Manufacturing
21 Jul 2008 | | Contributor(s):: Craig K. Svensson
The pharmaceutical industry is moving from a model of fully integrated pharmaceutical companies to fully networked pharmaceutical companies. In this latter model, major pharmaceutical companies are increasingly relying on partnerships for critical elements in the drug development process. This...
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Quality by Design and Process Analytical Technology for Pharmaceutical Manufacturing in the 21st Century
21 Jul 2008 | | Contributor(s):: Stephen R. Byrn
PAT or Process Analytical Technology is an initiative and guidance from the U.S. FDA to encourage modernization of pharmaceutical manufacturing. In reality, PAT is a subset of the larger concept of Quality by Design which is the implementation of design concepts for pharmaceutical dosage forms...
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Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations
21 Jul 2008 | | Contributor(s):: Stephen R. Byrn
Nanoparticles hold great promise for drug delivery applications. Several polymer-based formulations containing nanoparticles are in late phase development or on the market. In fact, polymer dispersions provide one of the best methods to prepare nanoparticles of small-molecule organic drugs....
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Multiplex Detection of Cell Surface Markers using Plasmonic Sensors
21 Jul 2008 | | Contributor(s):: Joseph M K Irudayaraj
Gold nanorod molecular probes (GNrMPs) were designed and fabricated for multiplex identification of cell surface markers in HBECs. Cells were probed directly using dark field microscopy integrated with a spectral imager for simultaneous detection of up to three surface markers. The...
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Discovery Park at Purdue University: Engine for Academic and Commercial Growth
10 Jul 2008 | | Contributor(s):: Charles Buck, Pankaj Sharma
The Bindley Bioscience Center and Birck Nanotechnology Center at Discovery Park blend life sciences and engineering research to cultivate and support innovative, multi-investigator, interdisciplinary research teams. Discovery Park engages researchers in a broader perspective with applications of...
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Funding Opportunities for Bilateral Activities between USA and India
09 Jul 2008 | | Contributor(s):: Arabinda Mitra
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Today's Scientific Scenario and Tomorrow's Challenges: The Case for India
09 Jul 2008 | | Contributor(s):: C.N.R. Rao
It is instructive and useful to examine the state of science in the country after 60 years of independence. What one sees is a curious mixture of successes and disappointments, and yet, one cannot but marvel at the great imagination of Pandit Nehru and the Parliament for having committed India to...
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Some Important Aspects of the Chemistry of Nanomaterials
01 Jul 2008 | | Contributor(s):: C.N.R. Rao
Keynote address for the launch of the Center for Analytical Instrumentation Development.
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NCN Nanophotonics: Research Seminars
20 Jun 2008 |
Many research seminars are available on the nanoHUB. Listed below are a few that discuss new optical properties and metamaterial device possiblities.
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NCN Nano-Devices for Medicine and Biology: Research Seminars
19 Jun 2008 |
Many research seminars are available on the nanoHUB. Listed below are a few that discuss new device possiblities.
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NCN Nano-Devices for Medicine and Biology: Simulation Tools for Research
19 Jun 2008 |
Many simulation tools are available on the nanoHUB. The tools have been well-tested and here include supporting materials so that they can be effectively used for research. The research tools include a first time users guide and supporting publications and theses.
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High-Aspect-Ratio Micromachining of Titanium: Enabling New Functionality and Opportunity in Micromechanical Systems Through Greater Materials Selection
18 Jun 2008 | | Contributor(s):: Masa Rao
Traditionally, materials selection has been limited in high-aspect-ratio micromechanical applications, due primarily to the predominance of microfabrication processes and infrastructure dedicated to silicon. While silicon has proven to be an excellent material for many of these applications, no...