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The safe and successful application of nanotechnology in the biological realm remains a challenge due to the inherent multi-scale nature of biology. Engineering nanoBIO devices requires the knowledge of how nanotechnology-based devices interact with biological systems at the protein, cell, tissue, and organ levels. The Engineered nanoBIO node at Indiana University (IU) develops a powerful set of integrated computational nanotechnology products that address this complex, multiscale problem in both education and research and facilitate the discovery of customized, efficient, and safe nanoscale devices for biological applications. These apps, tools, and frameworks span the range from nanoscale particles (nano) to cellular scale structures (micro) to tissue scale morpohologies (macro).

Featured App:

Nanoparticle Shape Lab

The shape of nanocontainers determines their ability to act as targeted drug delivery carriers by modulating their biodistribution and bioavailability.  This app simulates the shape deformation of soft-matter-based deformable, charged nanocontainers for a broad variety of nanocontainer material properties and solution conditions. Molecular dynamics based simulated annealing is used to minimize the energy of the nanocontainer for a given set of material and solution parameters.

Try the app here.


Apps 

Apps are standalone simulation tools run on nanoHUB's cloud. They range from simulations of behaviors of collections of nanoparticles smaller viruses up to the lifecycle and death of infected tissues.

Tools 

Tools enable you to run your own models or create your own apps.

Frameworks

Frameworks are sophisticated software packages at the heart of many of nanoBIO apps and tools. These packages are available offline for the most sophisticated nanobio simulations available today.

People

Meet the core team.

Education

Educational materials ranging from workshop talks to full curricular modules are available here.

Outreach

Learn about which events we've attended and upcoming events where you will be able to find us.

COVID-19 Resources

Apps, tools, and supporting resources for COVID-19 research and education.

 

Check nanoBIO node at Urbana for the products of the former nanoBIO node.